Abstract: Methods and systems for artificial intelligence based medical image segmentation are disclosed. In a method for autonomous artificial intelligence based medical image segmentation, a medical image of a patient is received. A current segmentation context is automatically determined based on the medical image and at least one segmentation algorithm is automatically selected from a plurality of segmentation algorithms based on the current segmentation context. A target anatomical structure is segmented in the medical image using the selected at least one segmentation algorithm.

Abstract: Methods and systems for acquiring a visualization of a target. For example, a computer-implemented method for acquiring a visualization of a target includes: generating a first sampling mask; acquiring first k-space data of the target at a first phase using the first sampling mask; generating a first image of the target based at least in part on the first k-space data; generating a second sampling mask using a model based on at least one selected from the first sampling mask, the first k-space data, and the first image; acquiring second k-space data of the target at a second phase using the second sampling mask; and generating a second image of the target based at least in part on the second k-space data.

Abstract: Embodiments of the disclosure provide systems and methods for generating a report based on a medical image of a patient. An exemplary system includes a communication interface configured to receive the medical image acquired by an image acquisition device. The system may further include at least one processor. The at least one processor is configured to automatically determine keywords from a natural language description of the medical image generated by applying a learning network to the medical image. The at least one processor is further configured to generate the report describing the medical image of the patient based on the keywords. The at least one processor is also configured to provide the report for display.

Abstract: Methods and systems for artificial intelligence based medical image segmentation are disclosed. In a method for autonomous artificial intelligence based medical image segmentation, a medical image of a patient is received. A current segmentation context is automatically determined based on the medical image and at least one segmentation algorithm is automatically selected from a plurality of segmentation algorithms based on the current segmentation context. A target anatomical structure is segmented in the medical image using the selected at least one segmentation algorithm.

Abstract: Embodiments of the disclosure provide systems and methods for generating a diagnosis report based on a medical image of a patient. The system includes a communication interface configured to receive the medical image acquired by an image acquisition device. The system further includes at least one processor. The at least one processor is configured to detect a medical condition based on the medical image and automatically generate text information describing the medical condition. The at least one processor is further configured to construct the diagnosis report, where the diagnosis report includes at least one image view showing the medical condition and a report view including the text information describing the medical condition. The system also includes a display configured to display the diagnosis report.

Abstract: A computer-implemented method for automatically detecting a target object from a 3D image is disclosed. The method may include receiving the 3D image acquired by an imaging device. The method may further include detecting, by a processor, a plurality of bounding boxes as containing the target object using a 3D learning network. The learning network may be trained to generate a plurality of feature maps of varying scales based on the 3D image. The method may also include determining, by the processor, a set of parameters identifying each detected bounding box using the 3D learning network, and locating, by the processor, the target object based on the set of parameters.

Abstract: Embodiments of the disclosure provide systems and methods for segmenting an image. An exemplary system includes a communication interface configured to receive the image acquired by an image acquisition device. The system further includes a memory configured to store a multi-level learning network comprising a plurality of convolution blocks cascaded at multiple levels. The system also includes a processor configured to apply a first convolution block and a second convolution block of the multi-level learning network to the image in series. The first convolution block is applied to the image and the second convolution block is applied to a first output of the first convolution block. The processor is further configured to concatenate the first output of the first convolution block and a second output of the second convolution block to obtain a feature map and obtain a segmented image based on the feature map.

Abstract: Embodiments of the disclosure provide systems and methods for detecting cancer metastasis in a whole-slide image. The system may include a communication interface configured to receive the whole-slide image and a learning model. The whole-slide image is acquired by an image acquisition device. The system may also include a memory configured to store a plurality of tiles derived from the whole-slide image in a queue. The system may further include at least one processor, configured to apply the learning model to at least two tiles stored in the queue in parallel to obtain detection maps each corresponding to a tile, and detect the cancer metastasis based on the detection maps.

Abstract: Embodiments of the disclosure provide systems and methods for generating a report based on medical images of a patient. An exemplary system includes a communication interface configured to receive the medical images acquired by an image acquisition device. The system may further include at least one processor. The at least one processor is configured to receive a user selection of at least one medical image in at least one view. The at least one processor is further configured to automatically generate keywords describing the selected medical image based on a learning network including a convolutional neural network and a recursive neural network connected in series. The at least one processor is also configured to receive a keyword selection among the generated keywords and generate the report based on the keyword selection. The exemplary system additionally includes a display configured to display the selected medical image and the report.

Abstract: Embodiments of the disclosure provide systems and methods for generating a diagnosis report based on a medical image of a patient. The system includes a communication interface configured to receive the medical image acquired by an image acquisition device. The system further includes at least one processor. The at least one processor is configured to detect a medical condition of the patient and parameters associated with the medical condition based on the medical image. The at least one processor is further configured to construct the diagnosis report based on the medical image, wherein the diagnosis report includes at least one view of the medical image and a description of the medical condition using the parameters. The system also includes a display configured to display the diagnosis report.

Abstract: A method for identifying a feature in a first image comprises establishing an initial database of image triplets, and in a pose estimation processor, training a deep learning neural network using the initial database of image triplets, calculating a pose for the first image using the deep learning neural network, comparing the calculated pose to a validation database populated with images data to identify an error case in the deep learning neural network, creating a new set of training data including a plurality of error cases identified in a plurality of input images and retraining the deep learning neural network using the new set of training data. The deep learning neural network may be iteratively retrained with a series of new training data sets. Statistical analysis is performed on a plurality of error cases to select a subset of the error cases included in the new set of training data.

Abstract: Embodiments of the disclosure provide systems and methods for segmenting a medical image. An exemplary system includes a communication interface configured to receive the medical image acquired by an image acquisition device. The system further includes a memory configured to store a multi-level learning network including at least a first convolution block and a second convolution block. The second convolution block has at least one convolution layer. The system also includes a processor. The processor is configured to determine a first feature map by applying the first convolution block to the medical image, and determine a second feature map by applying the second convolution block to the first feature map. The processor is further configured to determine a first level feature map by concatenating the first feature map and the second feature map. The processor is also configured to obtain a first level segmented image based on the first level feature map.

Abstract: Embodiments of the disclosure provide systems and methods for segmenting a medical image. The system includes a communication interface configured to receive the medical image acquired by an image acquisition device. The system also includes a memory configured to store a plurality of learning networks jointly trained using first training images of a first imaging modality and second training images of a second imaging modality. The system further includes a processor, configured to segment the medical image using a segmentation network selected from the plurality of learning networks.

Abstract: A method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a DHM image acquired using a digital holographic microscopy system and identifying one or more erythrocytes in the DHM image. For each respective erythrocyte included in the one or more erythrocytes, a cell thickness value for the respective erythrocyte using a parametric model is estimated, and a cell volume value is calculated for the respective erythrocyte using the cell thickness value.

Abstract: Systems and methods for image classification include receiving imaging data of in-vivo or excised tissue of a patient during a surgical procedure. Local image features are extracted from the imaging data. A vocabulary histogram for the imaging data is computed based on the extracted local image features. A classification of the in-vivo or excised tissue of the patient in the imaging data is determined based on the vocabulary histogram using a trained classifier, which is trained based on a set of sample images with confirmed tissue types.

Abstract: A method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a plurality of DHM images acquired using a digital holographic microscopy system. One or more connected components are identified in each of the plurality of DHM images and one or more training white blood cell images are generated from the one or more connected components. A classifier is trained to identify a plurality of white blood cell types using the one or more training white blood cell images. The classifier may be applied to a new white blood cell image to determine a plurality of probability values, each respective probability value corresponding to one of the plurality of white blood cell types. The new white blood cell image and the plurality of probability values may then be presented in a graphical user interface.

Abstract: A method of characterizing a serum and plasma portion of a specimen in regions occluded by one or more labels. The characterization may be used for Hemolysis, Icterus, and/or Lipemia, or Normal detection. The method captures one or more images of a labeled specimen container including a serum or plasma portion, processes the one or more images to provide segmentation data and identification of a label-containing region, and classifying the label-containing region with a convolutional neural network (CNN) to provide a pixel-by-pixel (or patch-by-patch) characterization of the label thickness count, which may be used to adjust intensities of regions of a serum or plasma portion having label occlusion. Optionally, the CNN can characterize the label-containing region as one of multiple pre-defined label configurations. Quality check modules and specimen testing apparatus adapted to carry out the method are described, as are other aspects.

Abstract: A method of characterizing a serum and plasma portion of a specimen in regions occluded by one or more labels. The characterization may be used for determining Hemolysis (H), Icterus (I), and/or Lipemia (L), or Normal (N) of a serum or plasma portion of a specimen. The method includes capturing one or more images of a labeled specimen container including a serum or plasma portion, processing the one or more images with a convolutional neural network to provide a determination of Hemolysis (H), Icterus (I), and/or Lipemia (L), or Normal (N). In further embodiments, the convolutional neural network can provide N-Class segmentation information. Quality check modules and testing apparatus adapted to carry out the method are described, as are other aspects.

Abstract: Systems and methods for image classification include receiving imaging data of in-vivo or excised tissue of a patient during a surgical procedure. Local image features are extracted from the imaging data. A vocabulary histogram for the imaging data is computed based on the extracted local image features. A classification of the in-vivo or excised tissue of the patient in the imaging data is determined based on the vocabulary histogram using a trained classifier, which is trained based on a set of sample images with confirmed tissue types.

Abstract: Embodiments can provide a method for atlas-based contouring, comprising constructing a relevant atlas database; selecting one or more optimal atlases from the relevant atlas database; propagating one or more atlases; fusing the one or more atlases; and assessing the quality of one or more propagated contours.