Abstract: A peripherally inserted central catheter (PICC) line arm sleeve with a window-style opening design or slip-on structured design. The sleeve has treated mesh fabric, with properties including, but not limited to, anti-bacterial, odor-resistant, moisture-wicking, and breathability, to cover the PICC insertion area. Treated and non-treated solid fabric may be used in the body of the sleeve. Treated solid fabric used has the same properties as treated mesh fabric. Use of the sleeve is not limited but targets survivors undergoing treatment for cancer(s), infectious disease(s), and other medical issues that use PICC lines in the treatment plan.