Patents by Inventor Shannon Alicia Marshall

Shannon Alicia Marshall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BMP-7 variants with improved properties
    Patent number: 7459527
    Abstract: The invention relates to variants of BMP-7 with improved properties and methods for their use.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: December 2, 2008
    Assignee: Xencor, Inc.
    Inventors: John R. Desjarlais, Shannon Alicia Marshall, Jonathan Zalevsky
  • BMP-4 variants with improved properties
    Publication number: 20080070837
    Abstract: The invention relates to variants of BMP-4 with improved properties and methods for their use.
    Type: Application
    Filed: June 20, 2006
    Publication date: March 20, 2008
    Applicant: Xencor, Inc.
    Inventors: John R. Desjarlais, Shannon Alicia Marshall, Jonathan Zalevsky
  • Novel proteins with altered immunogenicity
    Publication number: 20040230380
    Abstract: The present invention provides methods for combining computational methods for modulating protein immunogenicity with computational methods for identifying sequences with desired structural and functional properties. More specifically, the methods of the present invention may be used to identify modifications that increase or decrease the immunogenicity of a protein by affecting antigen uptake, MHC binding, T-cell binding, or antibody binding, while retaining or enhancing functional properties.
    Type: Application
    Filed: January 8, 2004
    Publication date: November 18, 2004
    Applicant: Xencor
    Inventors: Arthur J. Chirino, Bassil I. Dahiyat, John Rudolph Desjarlais, Shannon Alicia Marshall
  • Novel proteins with antiviral, antineoplastic, and/or immunomodulatory activity
    Publication number: 20040175359
    Abstract: The invention relates to interferon variants with improved properties and methods for their use.
    Type: Application
    Filed: September 30, 2003
    Publication date: September 9, 2004
    Inventors: John Rudolph Desjarlais, Shannon Alicia Marshall, Yirong Mo, Adam Read Thomason
  • Interferon variants with improved properties
    Publication number: 20040137581
    Abstract: The invention relates to interferon variants with improved properties and methods for their use.
    Type: Application
    Filed: September 30, 2003
    Publication date: July 15, 2004
    Applicant: Xencor
    Inventors: Anna Marie Aguinaldo, Amelia Joy Beyna, Ho Sung Cho, John Rudolph Desjarlais, Shannon Alicia Marshall, Umesh Muchhal, Michael Francis Aquino Villegas, Eugene Zhukovsky
  • Thrombopoiesis-stimulating proteins having reduced immunogenicity
    Publication number: 20040121953
    Abstract: The present invention relates to variant thrombopoietin proteins that possess thrombopoiesis-stimulating activity and have reduced immunogenicity. In particular, variants of thrombopoietin with reduced ability to bind one or more human class II MHC molecules are described.
    Type: Application
    Filed: August 11, 2003
    Publication date: June 24, 2004
    Inventors: Arthur J. Chirino, Jamal El Yazal, Shannon Alicia Marshall, Peter McDonnell, Jost Vielmetter
  • Antibody optimization
    Publication number: 20040110226
    Abstract: The present invention relates to the use of computational screening methods to optimize the physico-chemical properties of antibodies, including stability, solubility, and antigen binding affinity.
    Type: Application
    Filed: March 3, 2003
    Publication date: June 10, 2004
    Applicant: Xencor
    Inventors: Gregory Alan Lazar, John Rudolf Desjarlais, Shannon Alicia Marshall, Bassil I. Dahiyat