Patents by Inventor Shannon Biros

Shannon Biros has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL SCAFFOLDS FOR ALPHA-HELIX MIMICRY
    Publication number: 20090298835
    Abstract: Functionalized pyridazine derivatives having a low molecular weight and pharmaceutical compositions thereof are useful as alpha-helix mimetics and for treating conditions and/or disorders mediated by alpha-helix-binding receptors and proteins.
    Type: Application
    Filed: July 15, 2009
    Publication date: December 3, 2009
    Applicant: The Scripps Research Institute
    Inventors: Julius Rebek, JR., Shen Gu, Shannon Biros
  • Scaffolds for ?-helix mimicry
    Patent number: 7579350
    Abstract: Functionalized pyridazine derivatives having a low molecular weight and pharmaceutical compositions thereof are useful as alpha-helix mimetics and for treating conditions and/or disorders mediated by alpha-helix-binding receptors and proteins.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: August 25, 2009
    Assignee: The Scripps Research Institute
    Inventors: Julius Rebek, Jr., Shen Gu, Shannon Biros
  • OXAZOLE-PYRROLE-PIPERAZINE ALPHA-HELIX MIMETIC
    Publication number: 20090197895
    Abstract: Amphiphilic ?-helix mimetics are provided. These compounds are constructed using an oxazole-pyrrole-piperazine (OPP) scaffold. The amphiphilic ?-helix mimetics are also employable for making libraries and for treating diseases or conditions effected by the inhibition or disruption of interactions with the alpha helix of a protein.
    Type: Application
    Filed: January 30, 2009
    Publication date: August 6, 2009
    Applicant: The Scripps Research Institute
    Inventors: Julius Rebek, JR., Shannon Biros, Lionel Moisan, Severin Odermatt
  • Pyridazine based alpha-helix mimetics
    Publication number: 20090069334
    Abstract: The synthesis of new ?-helix scaffolds mimicking i, i+3 or i+4, i+7 residues, was accomplished. The common pyridazine heterocycle originates from the easily available building block, 6. These scaffolds may be thought of as synthetic counterparts of amphiphilic ?-helices having a “wet face” along one side and a hydrophobic face along the other side of the helix.
    Type: Application
    Filed: August 13, 2008
    Publication date: March 12, 2009
    Applicant: The Scripps Research Institute
    Inventors: Julius Rebek, JR., Shannon Biros, Lionel Moisan, Alessandro Volonterio, Enrique Mann, Trevor Dale
  • Novel scaffolds for beta-helix mimicry
    Publication number: 20060205728
    Abstract: Functionalized pyridazine derivatives having a low molecular weight and pharmaceutical compositions thereof are useful as alpha-helix mimetics and for treating conditions and/or disorders mediated by alpha-helix-binding receptors and proteins.
    Type: Application
    Filed: March 3, 2006
    Publication date: September 14, 2006
    Applicant: The Scripps Research Institute
    Inventors: Julius Rebek, Shen Gu, Shannon Biros