Abstract: A display panel including a pixel circuit and a light-emitting element, the pixel circuit including a driving transistor, a data writing transistor, a threshold compensation transistor, a first reset transistor, a bias transistor, and a light-emitting control module, the data writing transistor being electrically connected to a first terminal of the driving transistor, the threshold compensation transistor being connected in series between a gate of the driving transistor and a second terminal of the driving transistor, and configured to detect and self-compensate a threshold voltage deviation of the driving transistor, the first reset transistor and the bias transistor being electrically connected to the second terminal of the driving transistor, the light-emitting control module being connected in series with the driving transistor and the light-emitting element to control whether a driving current flows through the light-emitting element, the data writing transistor and the first reset transistor having th

Abstract: The present disclosure provides compositions and methods for the detection and identification of target nucleic acids within a tissue sample using fluorescent probes, wherein the probes comprise a target-binding domain and a barcode domain.

Abstract: Provided is a binding molecule specific for LIF and use thereof. Specifically, provided is an isolated antibody or an antigen-binding fragment thereof that binds to LIF and inhibits the activity of LIF. Also provided are uses of the isolated antibody or the antigen-binding fragment thereof in treatment of diseases.

Abstract: The present disclosure concerns embodiments related to methods of enriching particular DNA for analysis of methylation status and/or profiles, for example in the process of diagnosis of cancer. In particular embodiments, the methods utilize cell-free DNA as a source of DNA instead of genomic DNA and allow for focused enrichment of fragments having two or more enzyme digestion sites and containing at least one CpG site.

Abstract: Disclosed are compounds of formula (I), formula (II), and formula (III): wherein Ar, R1, A, and X are as defined in the specification. These compounds are antiviral agents and are contemplated for use in the treatment of viral infections, for example, hepatitis C. These compounds are also contemplated for use in treating or preventing cancers.

Abstract: Disclosed are compounds of formula (I), formula (II), and formula (III): wherein Ar, R1, A, and X are as defined in the specification. These compounds are antiviral agents and are contemplated for use in the treatment of viral infections, for example, hepatitis C. These compounds are also contemplated for use in treating or preventing cancers.

Abstract: Disclosed are compounds of formula (I) (formula I), as antiviral agents, antineoplastic agents, pharmaceutical compositions comprising such compounds, and a method of use of these compounds, wherein X and Y are independently CH or N, o is 0, 1 or 2, and E is absent or is (CR13R14)m, NH, or S, F is absent or is (CR15R16)n, C=O, or —SO2—, G is absent or is (CR17 CR18)r, H is absent or is C?O, or —SO2- and R1, Ar1, Ar2 are as defined in the specification. These compounds are antiviral agents and are contemplated in the treatment of viral infections, for example, hepatitis C, or are antineoplastic agents.