Patents by Inventor Shao-En Ong

Shao-En Ong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACOPROTEOMICS PLATFORM IDENTIFYING KINOME FEATURES REGULATING DRUG RESPONSE IN CANCER
    Publication number: 20210348171
    Abstract: The disclosure provides methods and compositions for increasing sensitivity, or decreasing resistance, of cancer cells to chemotherapeutic agents such as kinase inhibitor agents. In some embodiments, the cancer cells are hepatocellular carcinoma (HCC) cells. The methods and compositions can be integrated into methods of treatment of a subject with cancer, which can further comprise administering a chemotherapeutic agent such as kinase inhibitor agents. In another aspect, the disclosure provides a method for profiling the kinome of a cell or group of similar cells that incorporates kinase capture reagents and mass spectrometry analysis.
    Type: Application
    Filed: May 6, 2021
    Publication date: November 11, 2021
    Applicants: University of Washington, Fred Hutchinson Cancer Research Center
    Inventors: Shao-En Ong, Martin Golkowski, Ho-Tak Lau, Taranjit S. Gujral
  • Novel genes and expression products therefrom
    Publication number: 20060234290
    Abstract: The present invention relates generally to the identification of the products of gene expression in cancerous tissue or other tissue associated with an aberrant medical condition. Identification of such expression products enables the development of a range of diagnostic and therapeutic agents. In one embodiment of the present invention, a gene is differentially or preferentially expressed in cancerous tissue relative to normal tissue. Identification of the expression product of the gene and of the gene itself provides a means of developing diagnostic and therapeutic agents for the treatment, prophylaxis, and diagnosis of the cancerous condition in which the gene is differentially or preferentially expressed.
    Type: Application
    Filed: June 29, 2006
    Publication date: October 19, 2006
    Inventors: Ching Chung, Lily Chan, Keli Ou, Shao-En Ong, Teck Seow, Cynthia M.Y. Liang, Meng Choong, Li Tan
  • Novel genes and expression products therefrom
    Publication number: 20020107190
    Abstract: The present invention relates generally to the identification of the products of gene expression in cancerous tissue or other tissue associated with an aberrant medical condition. Identification of such expression products enables the development of a range of diagnostic and therapeutic agents. In one embodiment of the present invention, a gene is differentially or preferentially expressed in cancerous tissue relative to normal tissue. Identification of the expression product of the gene and of the gene itself provides a means of developing diagnostic and therapeutic agents for the treatment, prophylaxis, and diagnosis of the cancerous condition in which the gene is differentially or preferentially expressed.
    Type: Application
    Filed: February 21, 2001
    Publication date: August 8, 2002
    Inventors: Ching Ming Chung, Lily Chan, Keli Ou, Shao-En Ong, Teck Keong Seow, Cynthia Rosa M.Y. Liang, Meng Ling Choong, Li Kiang Tan