Patents by Inventor Shao-Jen Yeh
Shao-Jen Yeh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8309623Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.Type: GrantFiled: November 23, 2010Date of Patent: November 13, 2012Assignee: Industrial Technology Research InstituteInventors: Ya-Jen Yu, Chin-Fu Chen, Tsai-Yu Lin, Shao-Jen Yeh, Shian-Yih Wang, Po-Liang Lai
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Patent number: 8129188Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of: 2-hydroxyethylmathacrylate (HEMA), bisphenol A and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), ?,?-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.Type: GrantFiled: June 10, 2008Date of Patent: March 6, 2012Assignee: Industrial Technology Research InstituteInventors: Ming-Cheng Shih, Chin-Fu Chen, Rung-Jiun Gau, Yu-Shih Weng, Ya-Jen Yu, Shao-Jen Yeh
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Publication number: 20110065829Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.Type: ApplicationFiled: November 23, 2010Publication date: March 17, 2011Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ya-Jen YU, Chin-Fu CHEN, Tsai-Yu LIN, Shao-Jen YEH, Shian-Yih WANG, Po-Liang LAI
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Patent number: 7884142Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.Type: GrantFiled: February 27, 2009Date of Patent: February 8, 2011Assignee: Industrial Technology Research InstituteInventors: Ya-Jen Yu, Chin-Fu Chen, Tsai-Yu Lin, Shao-Jen Yeh, Shian-Yih Wang, Po-Liang Lai
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Patent number: 7749761Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of: 2-hydroxyethylmathacrylate (HEMA), bisphenolA and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), ?,?-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.Type: GrantFiled: June 5, 2006Date of Patent: July 6, 2010Assignee: Industrial Technology Research InstituteInventors: Ming-Cheng Shih, Chin-Fu Chen, Rung-Jiun Gau, Yu-Shih Weng, Ya-Jen Yu, Shao-Jen Yeh
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Publication number: 20090247666Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.Type: ApplicationFiled: February 27, 2009Publication date: October 1, 2009Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ya-Jen Yu, Chin Fu Chen, Tsai-Yu Lin, Shao-Jen Yeh, Shian-Yih Wang, Po-Liang Lai
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Publication number: 20090004731Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of: 2-hydroxyethylmathacrylate (HEMA), bisphenol A and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), ?,?-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.Type: ApplicationFiled: June 10, 2008Publication date: January 1, 2009Applicant: Industrial Technology Research InstituteInventors: Ming-Cheng Shih, Chin-Fu Chen, Rung-Jiun Gau, Yu-Shih Weng, Ya-Jen Yu, Shao-Jen Yeh
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Publication number: 20070072288Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of:2-hydroxyethylmathacrylate(HEMA),bisphenolA and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), ?,?-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.Type: ApplicationFiled: June 5, 2006Publication date: March 29, 2007Applicant: Industrial Technology Research InstituteInventors: Ming-Cheng Shih, Yu-Shih Weng, Chin-Fu Chen, Rung-Jiun Gau, Ya-Jen Yu, Shao-Jen Yeh