Abstract: An amide-based library is disclosed in the invention which is prepared via amide bond formation coupling an amine with a carboxylic acid. Also, a method using said library for screening a drug candidate is provided in the present invention. Compounds in the present invention having cytotoxicities are useful for a variety of therapeutic applications.

Abstract: The present invention is related to a precursor for no-carrier-added fluorine-18 labeled ethacrynic acid, N-(4-[18F]fluorobutyl)-Ethacrynic amide([18F]FBuEA) and the preparation method for HPLC non-radioactive standards. Its chemical structure is shown in the following: In the precursor, R1 represents a protective group for the amide functional group; R2 represents leaving group; or R1 represents carboxyl group, R2 represents p-tosyloxy, methane sulfonyloxy group or trifluoromethane sulfonyloxy group or bromine (Br). For the HPLC non-radioactive standards, R1 represents a protective group for the amide functional group and hydrogen, R2 represents fluorine.

Abstract: A method and system is provided for link layer scheduling for networked applications in a coordinator-based communications system. A network-coordinating device receives a request from a networked application to establish a communications session. The request includes a set of session parameters. The network-coordinating device allocates a first transmission opportunity in response to the request. The network-coordinating device allocates successive transmission opportunities based on the set of session parameters without receiving successive requests. The set of session parameters comprises at least one of a predetermined flow control mechanism, a quality-of-service (QoS) requirement, a bandwidth requirement, and an application type. In one embodiment, the predetermined flow control mechanism is additive increase and multiplicative decrease (AIMD) of transmission control protocol (TCP).

Abstract: A polishing head used for CMP is described, including a retaining ring that is for engaging with a wafer, a membrane and an edge control ring. The membrane includes a bottom part for engaging with the wafer, and a lip part contiguous with the bottom part. The edge control ring is disposed between the retaining ring and the membrane, including a bottom part that has an abutting surface. The abutting surface of the edge control ring contacts with the external surface of the lip part of the membrane when the membrane is not inflated.