Patents by Inventor Shao Weng Daniel TAN

Shao Weng Daniel TAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-CEACAM6 antibodies and methods of use
    Patent number: 11820821
    Abstract: The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: November 21, 2023
    Assignees: SINGAPORE HEALTH SERVICES PTE LTD, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Hau Wan Leung, Andre Boon Hwa Choo, Mei Yee Vanessa Ding, Shao Weng Daniel Tan, Narayanan Gopalakrishna Iyer
  • ANTI-CEACAM6 ANTIBODIES AND METHODS OF USE
    Publication number: 20220213189
    Abstract: The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.
    Type: Application
    Filed: December 22, 2021
    Publication date: July 7, 2022
    Inventors: Hau Wan Leung, Andre Boon Hwa CHOO, Mei Yee Vanessa DING, Shao Weng Daniel TAN, Narayanan Gopalakrishna IYER
  • Anti-CEACAM6 antibodies and methods of use
    Patent number: 11236160
    Abstract: The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: February 1, 2022
    Assignees: SINGAPORE HEALTH SERVICES PTE LTD, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Hau Wan Leung, Andre Boon Hwa Choo, Mei Yee Vanessa Ding, Shao Weng Daniel Tan, Narayanan Gopalakrishna Iyer
  • LIPID BIOMARKERS FOR THE DIAGNOSIS OF CANCER
    Publication number: 20190302118
    Abstract: The present disclosure provides a cancer biomarker for a patient suffering from pleural effusion, a method of determining whether a patient suffering from pleural effusion has cancer, and a method of treating cancer in a patient suffering from pleural effusion. Disclosed herein also include a cancer biomarker for the detection of cancer with EGFR mutation, a method of determining whether a patient suffering from cancer has EGFR mutation, and a method of treating cancer in a patient with EGFR mutation.
    Type: Application
    Filed: March 10, 2017
    Publication date: October 3, 2019
    Inventors: Ying Swan HO, Lian Yee YIP, Kiat Hon Tony LIM, Shao Weng Daniel TAN, Xulei YANG, Si Yong YEO
  • ANTI-CEACAM6 ANTIBODIES AND METHODS OF USE
    Publication number: 20190233514
    Abstract: The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.
    Type: Application
    Filed: October 10, 2017
    Publication date: August 1, 2019
    Inventors: Hau Wan LEUNG, Andre Boon Hwa CHOO, Mei Yee vanessa DING, Shao Weng Daniel Tan, Narayanan Gopalakrishna Iyer