Patents by Inventor Shaoling Zhao

Shaoling Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing insulinotropic GLP-1 (7-36) polypeptide and/or GLP-1 analogs
    Patent number: 7544512
    Abstract: The present invention discloses a method of producing polypeptides, including insulinotropic GLP-1 (7-36) polypeptide and/or GLP-1 analogs, by ligating genes in a tandem way. Also disclosed are the recombinant polypeptides produced by such a method. Using the method of this invention, 1 to 32 copies of GLP-1 (7-36) and/or GLP-1 analog genes may be expressed in tandem and the desired polypeptide can be obtained after cleavage of a fusion protein and further processes of separation and purification thus making possible the production of recombinant polypeptides, including recombinant GLP-1 (7-36) and/or GLP-1 analogs on a large scale, at a significantly reduced production cost.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: June 9, 2009
    Assignee: Shanhai Hua Yi Bio-Tech Lab
    Inventors: Yukun Sun, Dengxi Wu, Aizhen Wu, Zhiyong Zhu, Gang Yu, Jiaxiang Zhou, Shaoling Zhao
  • Method of producing insulinotropic GLP-1 (7-36) polypeptide and/or GLP-1 analogs
    Publication number: 20040146985
    Abstract: The present invention discloses a method of producing polypeptides, including insulinotropic GLP-1 (7-36) polypeptide and/or GLP-1 analogs, by ligating genes in a tandem way. Also disclosed are the recombinant polypeptides produced by such a method. Using the method of this invention, 1 to 32 copies of GLP-1(7-36) and/or GLP-1 analog genes may be expressed in tandem and the desired polypeptide can be obtained after cleavage of a fusion protein and further processes of separation and purification thus making possible the production of recombinant polypeptides, including recombinant GLP-1(7-36) and/or GLP-1 analogs on a large scale, at a significantly reduced production cost.
    Type: Application
    Filed: January 20, 2004
    Publication date: July 29, 2004
    Applicant: Shanghai Hua-Yi Bio-Tech Lab
    Inventors: Yukun Sun, Dengxi Wu, Aizhen Wu, Zhiyong Zhu, Gang Yu, Jiaxiang Zhou, Shaoling Zhao