Patents by Inventor Shaoping Li

Shaoping Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220257479
    Abstract: A gynecological vaginal wash for adjusting female vaginal microecology and a preparation method thereof, The wash is prepared by adding a natural fragrance to acidic water with an acidic water volume concentration of 0.01-0.5% and adjusting a pH value thereof to 3.5-5.5 after disinfection.
    Type: Application
    Filed: March 8, 2018
    Publication date: August 18, 2022
    Inventors: Shaoping Li, Li Shaoping
  • Publication number: 20210353757
    Abstract: Disclosed is a nanobody preparation system for administration through the internal and external epidermis of head and neck and internal epidermal layer of nasal cavity, comprising a specific nanobody having a biological activity and an antibody-drug carrier for improving the stability and tissue penetration of the nanobody. The drug carrier comprises one or more of a water-soluble macromolecular bio-saccharide gum substrate, polyvinyl alcohol, polyamino acid, glycerine, phospholipid, sodium carboxymethyl cellulose, collagen, and a hydrolase inhibitor.
    Type: Application
    Filed: October 26, 2017
    Publication date: November 18, 2021
    Inventors: Shaoping Li, Zhican QU
  • Publication number: 20190338044
    Abstract: The invention discloses a scheme for preparing some specific nanobody system and delivering nanobody medicine through woman's vagina as well as its preparation method and applications. Women's vagina is rich of capillaries and lymphatic vessels, vaginal permeability is greater than the rectum, mouth, and skin. Vaginal administration can not only local medication, but also systemic medication. Due to the unstable activity of traditional antibody or high molecular protein, large volume and other reasons, the biomedical administration mode is basically limited to the injection type. Nanobodies are the smallest units known to bind target antigens. The three-dimensional structure of nanobodies determines its relative stable biological activity, also nanobody has the characteristics of high temperature resistance, acid-base resistance, good water-solubility and strong tissue penetration.
    Type: Application
    Filed: September 8, 2017
    Publication date: November 7, 2019
    Inventors: Zhican Qu, Shaoping LI
  • Patent number: 10460751
    Abstract: A method and system provide a storage device. A plurality of read sensor stacks for each reader of the storage device are provided. The read sensor stacks are distributed along a down track direction and offset in a cross-track direction. A plurality of electronic lapping guides (ELGs) are provided for the read sensor stacks. The read sensor stacks are lapped. Lapping is terminated based on signal(s) from the ELG(s).
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: October 29, 2019
    Assignee: WESTERN DIGITAL (FREMONT), LLC
    Inventors: Steven C. Rudy, Christopher L. Beaudry, Shaoping Li
  • Publication number: 20190184012
    Abstract: The invention discloses a transdermal drug delivery scheme for preparing a specific nanobody biopharmaceutical through penetrating skin tissue, and its preparation method and application. Due to biological characteristics such as unstable activity of traditional antibodies or protein macromolecules, the administration of biopharmaceuticals is basically limited to injections. Nanobodies are the smallest units currently known to bind target antigens. The three-dimensional structure of nanobodies determines the relative stability of their structure and biological activity and their biological properties. Nanobodies have the characteristics of high temperature resistance, activity in a certain acid-base environment, good water solubility, and strong tissue penetration. Therefore, by optimizing the formulation of the carrier, the stability of the nanobody and the penetration of the skin tissue can be maintained and increased, so as to achieve a transdermal delivery formulation of the nanobody biopharmaceutical.
    Type: Application
    Filed: September 8, 2017
    Publication date: June 20, 2019
    Inventors: Zhican Qu, Shaoping LI
  • Publication number: 20180366171
    Abstract: Apparatuses, systems, and methods are disclosed for non-volatile memory. A plurality of layers of planar non-volatile memory cells forms a three-dimensional memory array. A plurality of word lines are coupled to planar non-volatile memory cells. Word lines may extend horizontally across layers of memory cells. A plurality of selector columns are coupled to planar non-volatile memory cells. Selector columns extend vertically through layers of memory cells, and may include central conductors surrounded by one or more concentric selective layers. One or more selective layers may permit an electrical current through a cell, between a word line and a central conductor, in response to a voltage satisfying a threshold.
    Type: Application
    Filed: June 19, 2017
    Publication date: December 20, 2018
    Applicant: SanDisk Technologies LLC
    Inventor: Shaoping Li
  • Patent number: 10157653
    Abstract: Apparatuses, systems, and methods are disclosed for non-volatile memory. A plurality of layers of planar non-volatile memory cells forms a three-dimensional memory array. A plurality of word lines are coupled to planar non-volatile memory cells. Word lines may extend horizontally across layers of memory cells. A plurality of selector columns are coupled to planar non-volatile memory cells. Selector columns extend vertically through layers of memory cells, and may include central conductors surrounded by one or more concentric selective layers. One or more selective layers may permit an electrical current through a cell, between a word line and a central conductor, in response to a voltage satisfying a threshold.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: December 18, 2018
    Assignee: SANDISK TECHNOLOGIES LLC
    Inventor: Shaoping Li
  • Patent number: 10121501
    Abstract: A magnetic read apparatus includes a read sensor, a shield structure and a side magnetic bias structure. The read sensor includes a free layer having a side and a nonmagnetic spacer layer. The shield structure includes a shield pinning structure and a shield reference structure. The nonmagnetic spacer layer is between the shield reference structure and the free layer. The shield reference structure is between the shield pinning structure and the nonmagnetic spacer layer. The shield pinning structure includes a pinned magnetic moment in a first direction. The shield reference structure includes a shield reference structure magnetic moment weakly coupled with the pinned magnetic moment. The side magnetic bias structure is adjacent to the side of the free layer.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: November 6, 2018
    Assignee: Western Digital (Fremont), LLC
    Inventors: Gerardo A. Bertero, Shaoping Li, Qunwen Leng, Yuankai Zheng, Rongfu Xiao, Ming Mao, Shihai He, Miaoyin Wang
  • Patent number: 10115419
    Abstract: A method and system provide a magnetic transducer having an air-bearing surface (ABS). The method includes providing a first shield, a first read sensor, an antiferromagnetically coupled (AFC) shield that includes an antiferromagnet, a second read sensor and a second shield. The read sensors are between the first and second shields. The AFC shield is between the read sensors. An optional anneal for the first shield is in a magnetic field at a first angle from the ABS. Anneals for the first and second read sensors are in magnetic fields in desired first and second read sensor bias directions. The AFC shield anneal is in a magnetic field at a third angle from the ABS. The second shield anneal is in a magnetic field at a fifth angle from the ABS. The fifth angle is selected based on a thickness and a desired AFC shield bias direction for the antiferromagnet.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: October 30, 2018
    Assignee: WESTERN DIGITAL (FREMONT), LLC
    Inventors: Rongfu Xiao, Shihai He, Daniele Mauri, Ming Mao, Shaoping Li
  • Publication number: 20180268847
    Abstract: A method and system provide a storage device. A plurality of read sensor stacks for each reader of the storage device are provided. The read sensor stacks are distributed along a down track direction and offset in a cross-track direction. A plurality of electronic lapping guides (ELGs) are provided for the read sensor stacks. The read sensor stacks are lapped. Lapping is terminated based on signal(s) from the ELG(s).
    Type: Application
    Filed: May 24, 2018
    Publication date: September 20, 2018
    Inventors: Steven C. RUDY, Christopher L. BEAUDRY, Shaoping LI
  • Patent number: 10068601
    Abstract: A magnetic read apparatus includes a media-facing surface (MFS), a sensor, a shield structure, a side bias structure, and a shield reference bias structure. The sensor includes a free layer and a nonmagnetic layer. The shield structure includes a shield pinning structure and a shield reference structure between the shield pinning structure and the nonmagnetic layer. The nonmagnetic layer is between the free layer and a shield reference structure. The shield pinning structure includes a pinned moment oriented in a first direction. The shield reference structure includes a reference structure moment weakly coupled with the pinned moment. The side bias structure is adjacent to a side of the free layer and biases the free layer in a first direction parallel to the MFS. The shield reference bias structure is adjacent to the shield reference structure and biases the shield reference structure in a direction opposite to the first direction.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: September 4, 2018
    Assignee: Western Digital (Fremont), LLC
    Inventors: Shaoping Li, Shihai He, Gerardo A. Bertero, Ming Mao, Yuankai Zheng, Anup Ghosh Roy, Chen-Jung Chien, Zhihong Zhang
  • Patent number: 10008222
    Abstract: A method and system provide a storage device. A plurality of read sensor stacks for each reader of the storage device are provided. The read sensor stacks are distributed along a down track direction and offset in a cross-track direction. A plurality of electronic lapping guides (ELGs) are provided for the read sensor stacks. The read sensor stacks are lapped. Lapping is terminated based on signal(s) from the ELG(s).
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: June 26, 2018
    Assignee: Western Digital (Fremont), LLC
    Inventors: Steven C. Rudy, Christopher L. Beaudry, Shaoping Li
  • Publication number: 20180151210
    Abstract: The present disclosure relates to a hybrid spin-transfer torque (STT) and spin-bit torque (SOT) magnetic random access memory (MRAM). The cells of the hybrid STT-SOT MRAM has magnetic tunnel junctions (MTJs) with some ferromagnetic multilayers whose magnetization is oriented perpendicular to the plane of the substrate and some ferromagnetic multilayers whose magnetization is aligned within the plane of the substrate. The architecture results in high density memory. The hybrid STT-SOT MRAM lowers the programming current density while having a high switching speed higher thermal stability.
    Type: Application
    Filed: November 30, 2016
    Publication date: May 31, 2018
    Inventors: Shaoping LI, Hong TSAI
  • Patent number: 9950020
    Abstract: Disclosed are the action and use of water extracts and polysaccharides from Fusarium oxysporum in immune enhancement, which belong to the field of biological medicine. The water extracts and polysaccharides from Fusarium oxysporum have a significant immune enhancement effect, which can promote the proliferation of macrophages, increase the phagocytic ability of macrophages, activate macrophages to release immunological active factors NO, IL-1? and TNF-? and can be used in lower immune function diseases and tumor adjuvant treatment.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: April 24, 2018
    Assignee: UNIVERSITY OF MACAU
    Inventors: Shaoping Li, Kun Feng, Lanzhen Meng, Jing Zhao
  • Patent number: 9830936
    Abstract: A tunnel magnetoresistance (TMR) read sensor having a tabbed AFM layer and an extended pinned layer and methods for making the same are provided. The TMR read sensor has an AFM layer recessed from the air bearing surface, providing a reduced shield-to-shield distance.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: November 28, 2017
    Assignee: WESTERN DIGITAL (FREMONT), LLC
    Inventors: Shaoping Li, Yuankai Zheng, Gerardo A. Bertero, Qunwen Leng, Michael L. Mallary, Rongfu Xiao, Ming Mao, Zhihong Zhang, Anup G. Roy, Chen Jung Chien, Zhitao Diao, Ling Wang
  • Publication number: 20170337941
    Abstract: A method and system provide a magnetic transducer having an air-bearing surface (ABS). The method includes providing a first shield, a first read sensor, an antiferromagnetically coupled (AFC) shield that includes an antiferromagnet, a second read sensor and a second shield. The read sensors are between the first and second shields. The AFC shield is between the read sensors. An optional anneal for the first shield is in a magnetic field at a first angle from the ABS. Anneals for the first and second read sensors are in magnetic fields in desired first and second read sensor bias directions. The AFC shield anneal is in a magnetic field at a third angle from the ABS. The second shield anneal is in a magnetic field at a fifth angle from the ABS. The fifth angle is selected based on a thickness and a desired AFC shield bias direction for the antiferromagnet.
    Type: Application
    Filed: August 9, 2017
    Publication date: November 23, 2017
    Inventors: RONGFU XIAO, SHIHAI HE, DANIELE MAURI, MING MAO, SHAOPING LI
  • Publication number: 20170309300
    Abstract: A method and system provide a storage device. A plurality of read sensor stacks for each reader of the storage device are provided. The read sensor stacks are distributed along a down track direction and offset in a cross-track direction. A plurality of electronic lapping guides (ELGs) are provided for the read sensor stacks. The read sensor stacks are lapped. Lapping is terminated based on signal(s) from the ELG(s).
    Type: Application
    Filed: July 13, 2017
    Publication date: October 26, 2017
    Inventors: Steven C. RUDY, Christopher L. BEAUDRY, Shaoping LI
  • Patent number: 9786301
    Abstract: Apparatuses and methods for providing thin shields in a multiple sensor array are provided. One such apparatus is a magnetic read transducer including a first read sensor, a second read sensor, and a shield assembly positioned between the first read sensor and the second read sensor at an air bearing surface (ABS) of the magnetic read transducer, the shield assembly including a first shield layer assembly having a first footprint with a first area, and a second shield layer assembly having a second footprint with a second area, where the second area is greater than the first area.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: October 10, 2017
    Assignee: WESTERN DIGITAL (FREMONT), LLC
    Inventors: Shaoping Li, Gerardo A. Bertero, Steven C. Rudy, Shihai He, Ming Mao, Haiwen Xi, Srikanth Ganesan, Qunwen Leng, Ge Yi, Rongfu Xiao, Feng Liu, Lei Wang
  • Patent number: 9786305
    Abstract: A magnetic read apparatus includes a first sensor, a shield layer, an insulating layer, a shield structure and a second sensor. The shield layer is between the first sensor and the insulating layer. The shield structure is in the down track direction from the insulating layer. The shield structure includes a magnetic seed structure, a shield pinning structure and a shield reference structure. The magnetic seed structure adjoins the shield pinning structure. The shield pinning structure is between the shield reference structure and the magnetic seed structure. The second sensor includes a free layer and a nonmagnetic spacer layer between the shield reference structure and the free layer. The shield reference structure is between the shield pinning structure and the nonmagnetic spacer layer. The shield pinning structure includes a pinned magnetic moment. The shield reference structure includes another magnetic moment weakly coupled with the pinned magnetic moment.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: October 10, 2017
    Assignee: WESTERN DIGITAL (FREMONT), LLC
    Inventors: Shaoping Li, Shihai He, Gerardo A. Bertero, Ming Mao, Yuankai Zheng
  • Patent number: 9754613
    Abstract: A method and system provide a magnetic transducer having an air-bearing surface (ABS). The method includes providing a first shield, a first read sensor, an antiferromagnetically coupled (AFC) shield that includes an antiferromagnet, a second read sensor and a second shield. The read sensors are between the first and second shields. The AFC shield is between the read sensors. An optional anneal for the first shield is in a magnetic field at a first angle from the ABS. Anneals for the first and second read sensors are in magnetic fields in desired first and second read sensor bias directions. The AFC shield anneal is in a magnetic field at a third angle from the ABS. The second shield anneal is in a magnetic field at a fifth angle from the ABS. The fifth angle is selected based on a thickness and a desired AFC shield bias direction for the antiferromagnet.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: September 5, 2017
    Assignee: Western Digital (Fremont), LLC
    Inventors: Rongfu Xiao, Shihai He, Daniele Mauri, Ming Mao, Shaoping Li