Abstract: A novel process for the preparation of lactone derivatives, and intermediates thereof is described. The lactone derivatives are important precursors for the synthesis of anti-hepatitis C virus agents, including sofosbuvir.

Abstract: A novel process for the preparation of lactone derivatives, and intermediates thereof is described. The lactone derivatives are important precursors for the synthesis of anti-hepatitis C virus agents, including sofosbuvir.

Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.

Abstract: The present invention relates to a method for preparing (?)-huperzine A. The method involves: allowing a mixture of (±)-huperzine A obtained from chemical synthesis and a chiral acid to form (±)-huperzine A chiral acid salt under suitable conditions; recrystallizing the chiral acid salt from an organic solvent and basifying with an alkali to obtain optically pure (?)-huperzine A. The method is convenient to operate and suitable for industrial production. The chemical purity and optical purity of (?)-huperzine A obtained by the method are each greater than 99.5%, satisfying the requirement for raw pharmaceutical purity in the pharmaceutical industry.

Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.

Abstract: An electronic device and a direction switching method are described. The electronic device includes a housing having a first end and a second end, an audio input unit and an audio output unit. The electronic device has at least a first working direction and a second working direction, the direction from said first end to said second end is a reference direction when the electronic device is in the first working direction; and the direction from the second end to the first end is the reference direction when the electronic device is in the second working direction, wherein the audio input unit in a working state is located at the second end when the electronic device is in the first working direction; and the audio input unit in the working state is located at the first end when the electronic device is in the second working direction.

Abstract: The present invention relates to a method for preparing (?)-huperzine A. The method involves: allowing a mixture of (±)-huperzine A obtained from chemical synthesis and a chiral acid to form (±)-huperzine A chiral acid salt under suitable conditions; recrystallizing the chiral acid salt from an organic solvent and basifying with an alkali to obtain optically pure (?)-huperzine A. The method is convenient to operate and suitable for industrial production. The chemical purity and optical purity of (?)-huperzine A obtained by the method are each greater than 99.5%, satisfying the requirement for raw pharmaceutical purity in the pharmaceutical industry.

Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.

Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.

Abstract: A novel process for preparation of Rebaudioside D (RD), and other related naturally occurring sweeteners is provided. RD is a natural sweetening agent which can decrease the bitter aftertaste of steviol glycosides. The said process is suitable for commercial manufacturing by using readily available natural products and nontoxic reagents.

Abstract: The present invention discloses an aralkyl substituted piperidine or piperazine derivative and the use of the derivative in preparation of medicaments for treating schizophrenia and correlative psychoneuroses. It is shown by pharmacological tests that the derivative of the present invention has better antischizophrenic effect and less toxicity. Said derivative is a free base or salt of the compound having the following general formula.

Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.

Abstract: An electronic device and a direction switching method are described. The electronic device includes a housing having a first end and a second end, an audio input unit and an audio output unit. The electronic device has at least a first working direction and a second working direction, the direction from said first end to said second end is a reference direction when the electronic device is in the first working direction; and the direction from the second end to the first end is the reference direction when the electronic device is in the second working direction, wherein the audio input unit in a working state is located at the second end when the electronic device is in the first working direction; and the audio input unit in the working state is located at the first end when the electronic device is in the second working direction.

Abstract: A method for intercepting graphics device interface invocations by using filter driver which is transparent to graphics device interface engine and real display driver is disclosed. The method comprises steps of duplicating DDI function table returned from said real display driver, modifying DDI functions of said real display driver required for capturing screen update, creating auxiliary buffer area as updating buffer area for said screen update, and further processing said updating buffer area. With the method of the present invention, the support to video and 3D acceleration in the local computer can be realized by means of software, and the user can be provided with high-quality picture and display effect. Compared with the Mirror system in the prior art, since the present invention doesn't employ the Mirror system, the graphics device interface engine of the inventive system are not aware of the existence of the filter driver, the video and 3D acceleration function of the graphic card still remains.

Abstract: A method for acquiring graphics device interface data and DirectX data by use of a filter driver transparent to transparent to a graphics device interface engine, DirectX kernel and a real display driver is disclosed, the method comprises steps of: updating the graphics device interface, and acquiring the graphics device interface data by use of a corresponding graphics device interface function in the filter driver; acquiring, for DirectDraw in DirectX, DirectDraw application and video update data by intercepting frame switch and bit block transfer operations of DirectDraw part; acquiring, for Direct3D in DirectX, data of Direct3D application by intercepting the update interface of Direct3D part. With the method of present invention, an integral acquisition of Windows GDI and DirectX data can be achieved while DirectX function remains available.

Abstract: A method is provided for processing operation command in a computer that has a display and a host which includes a first display processing unit for local displaying and a second display processing unit for remote displaying. The operation command is from a remote data processing terminal. The method includes: receiving a first operation command from the data processing terminal, the first operation command being a power-on command; performing power-on of the computer, shielding the first display processing unit and loading only a driver of the second display processing unit according to first operation command; receiving a second operation command from the data processing terminal, the second operation command being not a power-on command; executing the second operation command to obtain operation results, the operation results being image data processed by the second display processing unit, and sending the operation results to the remote data processing terminal, for remote displaying.

Abstract: A projector for acquiring a coordinate of a bright spot includes a half transparent and half reflecting mirror (22), an imaging device (24), and a processing system (25). The half transparent and half reflecting mirror (22) is provided on a light path between the light source (21) and the zooming system (23). The imaging device (24) captures an external light ray reflected by the half transparent and half reflecting mirror (22). The processing system (25) acquires the coordinate of the bright spot according to the image of the image of the bright spot captured by the imaging device.

Abstract: The present invention discloses an aralkyl substituted piperidine or piperazine derivative and the use of the derivative in preparation of medicaments for treating schizophrenia and correlative psychoneuroses. It is shown by pharmacological tests that the derivative of the present invention has better antischizophrenic effect and less toxicity. Said derivative is a free base or salt of the compound having the following general formula.

Abstract: A projector for acquiring a coordinate of a bright spot includes a half transparent and half reflecting mirror (22), an imaging device (24), and a processing system (25). The half transparent and half reflecting mirror (22) is provided on a light path between the light source (21) and the zooming system (23). The imaging device (24) captures an external light ray reflected by the half transparent and half reflecting mirror (22). The processing system (25) acquires the coordinate of the bright spot according to the image of the image of the bright spot captured by the imaging device.

Abstract: The invention discloses a method for processing operation command in a computer and relates to a remote computer control technique. The invention is proposed for solving the problem that current remote computers can not be smoothly controlled. A technique solution employed is that the computer comprises a display and a host which includes a first display processing unit and a second display processing unit therein, said operation command is from a remote data processing terminal, the method comprises: receiving the operation command from said data processing terminal; shielding said first display processing unit according to said operation command; executing said operation command to obtain operation results; wherein said shielding said first display processing unit further comprises steps of: detecting said first display processing unit and said second display processing unit and loading only a driver of said second display processing unit. The invention also discloses a computer.