Patents by Inventor Shaoqing Yuan

Shaoqing Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aripiprazole type I microcrystal, aripiprazole solid preparations, and preparation method
    Patent number: 9073857
    Abstract: A method for preparing an aripiprazole type I microcrystal, including the following steps: dissolving aripiprazole in an acidifier, acquiring a medicament-having acid solution; adding an alkalizer while stirring, then adding water or aqueous ethanol 10 to 60 wt % while stirring, and separating by precipitation the aripiprazole type I microcrystal. Furthermore, a method for preparing a solid preparation having the aripiprazole type I microcrystal, an aripiprazole microcrystal having an average particle size of less than 20 ?m, and a solid preparation having the microcrystal. The method for preparing the aripiprazole type I microcrystal allows reduced pollution and loss, great safety, easy and convenient, reduced use of organic solvents, obviated need for demanding process conditions (such as cooling condition) and apparatus, low cost, and facilitated applicability in industrialized manufacturing.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: July 7, 2015
    Assignees: SHANGHAI ZHONGXI PHARMACEUTICAL CORPORATION, SHANGHAI ZHONGXI SUNVE PHARMACEUTICAL CO., LTD.
    Inventors: Siji Zheng, Bo Tan, Linyong Fu, Xiaoyi Liu, Shaoqing Yuan, Zhihui Cao
  • ARIPIPRAZOLE TYPE I MICROCRYSTAL, ARIPIPRAZOLE SOLID PREPARATIONS, AND PREPARATION METHOD
    Publication number: 20140135344
    Abstract: A method for preparing an aripiprazole type I microcrystal, including the following steps: dissolving aripiprazole in an acidifier, acquiring a medicament-having acid solution; adding an alkalizer while stirring, then adding water or aqueous ethanol 10 to 60 wt % while stirring, and separating by precipitation the aripiprazole type I microcrystal. Furthermore, a method for preparing a solid preparation having the aripiprazole type I microcrystal, an aripiprazole microcrystal having an average particle size of less than 24 ?m, and a solid preparation having the microcrystal. The method for preparing the aripiprazole type I microcrystal allows reduced pollution and loss, great safety, easy and convenient, reduced use of organic solvents, obviated need for demanding process conditions (such as cooling condition) and apparatus, low cost, and facilitated applicability in industrialized manufacturing.
    Type: Application
    Filed: June 26, 2012
    Publication date: May 15, 2014
    Applicants: SHANGHAI ZHONGXI SUNVE PHARMACEUTICAL CO., LTD., SHANGHAI ZHONGXI PHARMACEUTICAL CORPORATION
    Inventors: Siji Zheng, Bo Tan, Linyong Fu, Xiaoyi Liu, Shaoqing Yuan, Zhihui Cao