Patents by Inventor Shaoyi Jiang

Shaoyi Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10828398
    Abstract: Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: November 10, 2020
    Assignee: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Harihara Subramanian Sundaram, Andrew William Sinclair, Jean-René Ella-Menye, Priyesh Jain
  • Patent number: 10794921
    Abstract: Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: October 6, 2020
    Assignees: University of Washington, Puget Sound Blood Center
    Inventors: Daniel M. Ratner, Jill M. Johnsen, James T. Kirk, José A. López, Norman D. Brault, Shaoyi Jiang
  • Publication number: 20200289712
    Abstract: Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.
    Type: Application
    Filed: April 29, 2019
    Publication date: September 17, 2020
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Harihara Subramanian Sundaram, Andrew William Sinclair, Jean-René Ella-Menye, Priyesh Jain
  • Publication number: 20200253192
    Abstract: Zwitterionic microgels, zwitterionic microgel assemblies, their formulations and methods for their use.
    Type: Application
    Filed: July 20, 2017
    Publication date: August 13, 2020
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Andrew Sinclair, Mary Elizabeth O'Kelly, Tao Bai, Priyesh Jain
  • Publication number: 20200123294
    Abstract: N-oxide and monomers, N-oxide polymers and copolymers, methods for making the N-oxide monomers, polymers, and copolymers, compositions and materials that include N-oxide polymers and copolymers, and methods for using the N-oxide monomers, N-oxide polymers, and N-oxide copolymers.
    Type: Application
    Filed: June 29, 2018
    Publication date: April 23, 2020
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Priyesh Jain, Jinrong Ma
  • Patent number: 10544312
    Abstract: Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: January 28, 2020
    Assignee: University of Washington
    Inventors: Shaoyi Jiang, Yuting Li, Hong Xue, Shengfu Chen
  • Publication number: 20190219570
    Abstract: Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.
    Type: Application
    Filed: August 27, 2018
    Publication date: July 18, 2019
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Zheng Zhang, Shengfu Chen, Hana Vaisocherova
  • Patent number: 10301413
    Abstract: Nonfouling copolymers and hydrogels comprising positively charged repeating units or latent positively charged repeating units and negatively charged units or latent positively charged units.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: May 28, 2019
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Shaoyi Jiang, Shengfu Chen
  • Publication number: 20190154683
    Abstract: Hierarchical films with structurally regulated functionalities through the integration of two-dimensional and three-dimensional structures to achieve ultra low nonspecific binding and high loading of molecular recognition elements, and methods for making and using the films.
    Type: Application
    Filed: July 23, 2018
    Publication date: May 23, 2019
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Shaoyi Jiang, Norman David Brault, JR., Harihara S. Sundaram, Chun-Jen Huang, Qiuming Yu, Yuting Li
  • Patent number: 10272180
    Abstract: Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: April 30, 2019
    Assignee: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Harihara Subramanian Sundaram, Andrew William Sinclair, Jean-René Ella-Menye, Priyesh Jain
  • Publication number: 20190070300
    Abstract: Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates.
    Type: Application
    Filed: November 15, 2018
    Publication date: March 7, 2019
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Shaoyi Jiang, Andrew Keefe, Hong Xue
  • Publication number: 20190041410
    Abstract: Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined.
    Type: Application
    Filed: July 27, 2018
    Publication date: February 7, 2019
    Applicants: University of Washington through its Center for Commercialization, Bloodworks
    Inventors: Daniel M. Ratner, Jill M. Johnsen, James T. Kirk, José A. López, Norman D. Brault, Shaoyi Jiang
  • Publication number: 20190002625
    Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions.
    Type: Application
    Filed: June 2, 2016
    Publication date: January 3, 2019
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Jean-René Ella-Menye, Hsiang-Chieh Hung, Priyesh Jain, Andrew Sinclair, Harihara Subramanian Sundaram, Yang Li, Peng Zhang
  • Patent number: 10130716
    Abstract: Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: November 20, 2018
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Shaoyi Jiang, Andrew Keefe, Hong Xue
  • Patent number: 10073102
    Abstract: Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: September 11, 2018
    Assignees: University of Washington through its Center for Commercialization, Bloodworks
    Inventors: Daniel M. Ratner, Jill M. Johnsen, James T. Kirk, José A. López, Norman D. Brault, Shaoyi Jiang
  • Patent number: 10060918
    Abstract: Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: August 28, 2018
    Assignee: University of Washington
    Inventors: Shaoyi Jiang, Zheng Zhang, Shengfu Chen, Hana Vaisocherova
  • Patent number: 10031138
    Abstract: Hierarchical films with structurally regulated functionalities through the integration of two-dimensional and three-dimensional structures to achieve ultra low nonspecific binding and high loading of molecular recognition elements, and methods for making and using the films.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: July 24, 2018
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Shaoyi Jiang, Norman David Brault, Jr., Harihara S. Sundaram, Chun-Jen Huang, Qiuming Yu, Yuting Li
  • Publication number: 20170266350
    Abstract: Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.
    Type: Application
    Filed: September 9, 2015
    Publication date: September 21, 2017
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Harihara Subramanian Sundaram, Andrew William Sinclair, Jean-René Ella-Menye, Priyesh Jain
  • Patent number: 9738780
    Abstract: Zwitterionic crosslinking agents, crosslinked zwitterionic hydrogels prepared from copolymerization of zwitterionic monomers with the zwitterionic crosslinking agent, methods for making crosslinked zwitterionic hydrogels, and devices that include and methods that use the crosslinked zwitterionic hydrogels.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: August 22, 2017
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Shaoyi Jiang, Hong Xue, Wei Yang, Louisa R. Carr
  • Publication number: 20170227555
    Abstract: Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined.
    Type: Application
    Filed: February 17, 2017
    Publication date: August 10, 2017
    Applicants: University of Washington through its Center for Commercialization, Puget Sound Blood Center
    Inventors: Daniel M. Ratner, Jill M. Johnsen, James T. Kirk, José A. López, Norman D. Brault, Shaoyi Jiang