Abstract: The disclosure provides compositions and methods for the preparation, manufacture and use of an adeno-associated virus (AAV) particle for the vectorized delivery of an antibody molecule that binds to HER2.

Abstract: The present invention provides a micro-light night vision lens comprising a hollow cylinder body; a number of transition segments, communicated with each other provided in turn on an inner surface of the cylinder body along its axial extension direction; a plurality of lens units, provided in succession and at intervals at different positions on the inner surface of the cylinder body along the central axis direction thereof; a CCD unit, provided at one end of the cylinder body in the axial direction and located on the light-out side of the lens unit therein, and spaced apart from the cylinder body, the radial dimension of the CCD unit does not exceed the diameter of the lens unit at the other end of the cylinder body in the axial direction. By reasonably laying out the lens unit, the present invention obtains a larger effective focal length and imaging quality.

Abstract: The disclosure relates to compositions and methods for altering, e.g., enhancing, the expression of GCase proteins, whether in vitro and/or in vivo. Such compositions include delivery of an adeno-associated viral (AAV) particle. The compositions and methods of the present disclosure are useful in the treatment of subjects diagnosed with, or suspected of having Parkinson Disease or related condition resulting from a deficiency in the quantity and/or function of GBA gene product or associated with decreased expression or protein levels of GCase protein.

Abstract: The disclosure provides compositions and methods for the preparation, manufacture and use of an adeno-associated virus (AAV) particle for the vectorized delivery of an antibody molecule that binds to tau.

Abstract: The disclosure relates to compositions, formulations, and methods for the preparation, use, and/or formulation of adeno-associated virus capsid protein variants.

Abstract: A method and system for obtaining link node data is provided. The method is applied to an industrial control ring network system including a master station device and a plurality of node devices, and includes: after receiving a link fault message, the master station device determines to transmit a first link location acquisition message to a first network port and/or a second network port based on respective on-off states; each node device processes the first link location acquisition message to obtain and transmit a second link location acquisition message; the master station device parses the second link location acquisition message and transmits a first node data acquisition message; the node device processes the first node data acquisition message to obtain and transmit a second node data acquisition message; and the master station device parses the second node data acquisition message to obtain data of at least one node device.

Abstract: Disclosed is a shock absorption device for photoelectric instrument for gun, comprising a bracket, a buffer mechanism, and a connection mechanism; a card block is formed on the bracket, and a perforation is formed on the card block; the buffer mechanism includes a buffer seat, a slide bar, and a cushioning elastic; the connection mechanism is mounted on the bracket and used to be detachably connected to Picatinny rail on a sniper rifle. When shooting, the sniper rifle recoils, the sniper rifle drives the Picatinny rail to recoil, the Picatinny rail drives the bracket to recoil through the connection mechanism, the bracket acts on the cushioning elastic, and the cushioning elastic contracts, which can buffer the photoelectric instrument for the gun installed on the buffer seat, reduce the recoil of the photoelectric instrument for gun, and prolong its service life.

Abstract: The present disclosure discloses a method and an apparatus for data processing, a storage medium and an electronic device, where for each second unit in the embodiments of the present disclosure, a plurality of communication links are provided between the first unit and the second unit. The first unit, in response to a data operation request, sends the data operation request to the second unit through the plurality of communication links between the first unit and the second unit. The second unit processes the target data to be processed according to the data operation instruction in the data operation request to obtain a processing result, and sends the processing result to the first unit via a plurality of communication links. The first unit executes a response strategy for the data operation request based on the processing result.

Abstract: The present disclosure discloses a method, a device, a storage medium and a electronic device for data acquisition. The method for data acquisition comprises: determining an initial state for the target port and performing state monitoring; if the initial state is monitored to change, taking the changed state as the target state; upon monitoring the change of the initial state, after a first monitoring period, determining the completion of the jitters-eliminating for the signal received by the target port; and during a second monitoring period, determining whether a state for the target port monitored each time is the target state; if yes, taking the target state as a state for the target port and storing the target state; and performing data acquisition according to the stored state corresponding to the target port.

Abstract: The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.

Abstract: The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.

Abstract: Disclosed is a shock absorption device for photoelectric instrument for gun, comprising a bracket, a buffer mechanism, and a connection mechanism; a card block is formed on the bracket, and a perforation is formed on the card block; the buffer mechanism includes a buffer seat, a slide bar, and a cushioning elastic; the connection mechanism is mounted on the bracket and used to be detachably connected to Picatinny rail on a sniper rifle. When shooting, the sniper rifle recoils, the sniper rifle drives the Picatinny rail to recoil, the Picatinny rail drives the bracket to recoil through the connection mechanism, the bracket acts on the cushioning elastic, and the cushioning elastic contracts, which can buffer the photoelectric instrument for the gun installed on the buffer seat, reduce the recoil of the photoelectric instrument for gun, and prolong its service life.

Abstract: The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts tor enhanced tropism to a target tissue.

Abstract: The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.

Abstract: The disclosure in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

Abstract: The disclosure in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

Abstract: The present invention discloses a cloud-oriented stream scheduling method based on Android platform, which aims to solve the problem that the calculation and storage capability of the mobile terminal device are limited and the application has a low expandability. The technical solution of the present invention is to build a core scheduling routine and an App management routine in a mobile terminal device based on Android operation system, and build a cloud management service subsystem in cloud server to construct a cloud-oriented stream scheduling system based on the Android platform to make the mobile terminal device enabled to dynamically install or uninstall the applications according to security attribute, user behavior habit, network status and transmission quality, processing capability of current mobile terminal device, and timed task of the application and achieve the consistent application view on the level of the mobile terminal device.

Abstract: The present invention discloses a cloud-oriented stream scheduling method based on Android platform, which aims to solve the problem that the calculation and storage capability of the mobile terminal device are limited and the application has a low expandability. The technical solution of the present invention is to build a core scheduling routine and an App management routine in a mobile terminal device based on Android operation system, and build a cloud management service subsystem in cloud server to construct a cloud-oriented stream scheduling system based on the Android platform to make the mobile terminal device enabled to dynamically install or uninstall the applications according to security attribute, user behavior habit, network status and transmission quality, processing capability of current mobile terminal device, and timed task of the application and achieve the consistent application view on the level of the mobile terminal device.

Abstract: The present invention discloses a method for rapidly deploying an application based on a customized android platform, and is aimed to solve the problems of long installation time, high energy consumption, a slow system response, and poor user experience when installing an application in a mobile intelligent device running the Android system. The technical solutions are as below: building a system for rapidly deploying an application based on the customized Android platform, wherein the system includes a cloud application store running in a cloud server and an application store client running in a mobile intelligent device; improving the installation process of the application for the Android system, introducing the cloud application store and a store client, and incorporating an optimized target file into the APK file, wherein the optimized target file is needed when the mobile intelligent device runs the application.