Patents by Inventor Shaozhe GUO

Shaozhe GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Freeze-dried powder of high molecular weight silk fibroin, preparation method therefor and use thereof
    Patent number: 10533037
    Abstract: The invention discloses a freeze-dried powder of high molecular weight silk fibroin, preparation process and use thereof. The freeze-dried powder is obtained from silk by degumming, dissolution, dialysis, centrifugation, high temperature and high pressure treatment and freeze-drying. A method of preparing silk fibroin microspheres with polyethylene glycol comprises mixing a silk fibroin solution of 1-30 wt % with a PEG solution of 10-60 w % and incubating the resulting solution. A controlled-release or sustained-release silk fibroin gel formulation includes a gel-state carrier and a drug dispersed/adsorbed therein, the carrier is a silk fibroin gel formed by blending with LMW-PEG.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: January 14, 2020
    Assignees: SIMATECH INCORPORATION, TRUSTEES OF TUFTS COLLEGE
    Inventors: Xiaoqin Wang, Jian Liu, Jianbing Wu, Cheng Qian, Zhaozhu Zheng, Shaozhe Guo, Fuxin Shi, David Kaplan
  • FREEZE-DRIED POWDER OF HIGH MOLECULAR WEIGHT SILK FIBROIN, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20170107264
    Abstract: The invention discloses a freeze-dried powder of high molecular weight silk fibroin, preparation process and use thereof. The freeze-dried powder is obtained from silk by degumming, dissolution, dialysis, centrifugation, high temperature and high pressure treatment and freeze-drying. A method of preparing silk fibroin microspheres with polyethylene glycol comprises mixing a silk fibroin solution of 1-30 wt % with a PEG solution of 10-60 w % and incubating the resulting solution. A controlled-release or sustained-release silk fibroin gel formulation includes a gel-state carrier and a drug dispersed/adsorbed therein, the carrier is a silk fibroin gel formed by blending with LMW-PEG.
    Type: Application
    Filed: March 25, 2015
    Publication date: April 20, 2017
    Inventors: Xiaoqin WANG, Jian LIU, Jianbing WU, Cheng QIAN, Zhaozhu ZHENG, Shaozhe GUO, Fuxin SHI