Patents by Inventor Sharath Hosali
Sharath Hosali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11977257Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.Type: GrantFiled: August 22, 2022Date of Patent: May 7, 2024Assignee: Quantum-Si IncorporatedInventors: Ali Kabiri, Bing Shen, Gerard Schmid, James Beach, Kyle Preston, Sharath Hosali
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Publication number: 20220397720Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.Type: ApplicationFiled: August 22, 2022Publication date: December 15, 2022Applicant: Quantum-Si IncorporatedInventors: Ali Kabiri, Bing Shen, Gerard Schmid, James Beach, Kyle Preston, Sharath Hosali
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Patent number: 11454758Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.Type: GrantFiled: August 7, 2020Date of Patent: September 27, 2022Assignee: Quantum-Si IncorporatedInventors: Ali Kabiri, Bing Shen, Gerard Schmid, James Beach, Kyle Preston, Sharath Hosali
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Patent number: 11383269Abstract: A method of forming an ultrasonic transducer device includes forming a curved membrane over a transducer cavity. A center portion of the curved membrane is closer to a bottom surface of the transducer cavity than with respect to radially outwardly disposed portions of the curved membrane.Type: GrantFiled: June 9, 2020Date of Patent: July 12, 2022Assignee: BFLY OPERATIONS, INC.Inventors: Gerard Schmid, Sharath Hosali, James Beach, Jaime Scott Zahorian, Sarp Satir
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Publication number: 20220011486Abstract: Apparatus and methods relating to attenuating excitation radiation incident on a sensor in an integrated device that is used for sample analysis are described. At least one semiconductor film of a selected material and crystal morphology is located between a waveguide and a sensor in an integrated device that is formed on a substrate. Rejection ratios greater than 100 or more can be obtained for excitation and emission wavelengths that are 40 nm apart for a single layer of semiconductor material.Type: ApplicationFiled: September 23, 2021Publication date: January 13, 2022Applicant: Quantum-Si IncorporatedInventors: Michael Bellos, Faisal R. Ahmad, James Beach, Michael Coumans, Sharath Hosali, Ali Kabiri, Kyle Preston, Gerard Schmid, Bing Shen, Jonathan M. Rothberg
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Publication number: 20210215606Abstract: Systems and methods for optical power distribution within an integrated device, in a substantially uniform manner, to a large number of sample wells and/or other photonic elements. The integrated device and related instruments and systems may be used to analyze samples in parallel. The integrated device may include a grating coupler configured to receive light from an excitation source and optically couple with multiple waveguides configured to couple with sample wells. Vertical extents of optical modes of individual waveguides may be modulated to adjust confinement of light within the waveguides. This modulation may enable more uniform distribution of excitation light to the sample wells, improve excitation efficiency, and prevent overpower on regions of the integrated device.Type: ApplicationFiled: January 14, 2021Publication date: July 15, 2021Applicant: Quantum-Si IncorporatedInventors: Gerard Schmid, Sharath Hosali, James Beach, Kyle Preston, Ali Kabiri, Bing Shen
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Patent number: 10987500Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, electrodes and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.Type: GrantFiled: August 1, 2014Date of Patent: April 27, 2021Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Daniel Fine, Alessandro Grattoni, Mauro Ferrari, Xuewu Liu, Randal Goodall, Sharath Hosali
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Publication number: 20210041625Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.Type: ApplicationFiled: August 7, 2020Publication date: February 11, 2021Applicant: Quantum-Si IncorporatedInventors: Ali Kabiri, Bing Shen, Gerard Schmid, James Beach, Kyle Preston, Sharath Hosali
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Publication number: 20200384503Abstract: A method of forming an ultrasonic transducer device includes forming a curved membrane over a transducer cavity. A center portion of the curved membrane is closer to a bottom surface of the transducer cavity than with respect to radially outwardly disposed portions of the curved membrane.Type: ApplicationFiled: June 9, 2020Publication date: December 10, 2020Applicant: Butterfly Network, Inc.Inventors: Gerard Schmid, Sharath Hosali, James Beach, Jaime Scott Zahorian, Sarp Satir
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Publication number: 20200284957Abstract: Apparatus and methods relating to attenuating excitation radiation incident on a sensor in an integrated device that is used for sample analysis are described. At least one semiconductor film of a selected material and crystal morphology is located between a waveguide and a sensor in an integrated device that is formed on a substrate. Rejection ratios greater than 100 or more can be obtained for excitation and emission wavelengths that are 40 nm apart for a single layer of semiconductor material.Type: ApplicationFiled: March 5, 2020Publication date: September 10, 2020Applicant: Quantum-Si IncorporatedInventors: Michael Bellos, Faisal R. Ahmad, James Beach, Michael Coumans, Sharath Hosali, Ali Kabiri, Kyle Preston, Gerard Schmid, Bing Shen, Jonathan M. Rothberg
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Patent number: 10722696Abstract: A nano-scale device and method of manufacturing and use. The nano-scale device may be used in-vivo and may comprise a fluid path with an inlet microchannel, an outlet microchannel, and a nanochannel. The fluid path comprises a bio-robust material. In certain embodiments, the bio-robust material may be coated over a material that is not bio-robust.Type: GrantFiled: November 16, 2016Date of Patent: July 28, 2020Assignee: NANOMEDICAL SYSTEMS, INC.Inventors: Randy Goodall, Sharath Hosali
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Publication number: 20200173966Abstract: Methods and devices for enriching a molecular component within a sample. Certain embodiments include a rigid body, a malleable adhesive, and a nanoporous layer coupled to the rigid planar substrate.Type: ApplicationFiled: May 31, 2018Publication date: June 4, 2020Applicant: NANOMEDICAL SYSTEMS, INC.Inventors: Randy GOODALL, Sharath HOSALI, Stephanie PASAS-FARMER
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Publication number: 20170189658Abstract: A nano-scale device and method of manufacturing and use. The nano-scale device may be used in-vivo and may comprise a fluid path with an inlet microchannel, an outlet microchannel, and a nanochannel. The fluid path comprises a bio-robust material. In certain embodiments, the bio-robust material may be coated over a material that is not bio-robust.Type: ApplicationFiled: November 16, 2016Publication date: July 6, 2017Applicant: NANOMEDICAL SYSTEMS, INC.Inventors: Randy GOODALL, Sharath HOSALI
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Patent number: 9526824Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.Type: GrantFiled: May 2, 2013Date of Patent: December 27, 2016Assignees: The Board of Regents of the University of Texas System, The Ohio State University Research FoundationInventors: Mauro Ferrari, Xuewu Liu, Alessandro Grattoni, Daniel Fine, Randy Goodall, Sharath Hosali, Ryan Medema, Lee Hudson
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Publication number: 20150088102Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, electrodes and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.Type: ApplicationFiled: August 1, 2014Publication date: March 26, 2015Inventors: Daniel FINE, Alessandro GRATTONI, Mauro FERRARI, Xuewu LIU, Randal GOODALL, Sharath HOSALI
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Publication number: 20130240483Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.Type: ApplicationFiled: May 2, 2013Publication date: September 19, 2013Applicants: The Ohio State University Research Foundation, The Board of Regents of the University of Texas SystemInventors: Mauro FERRARI, Xuewu LIU, Alessandro GRATTONI, Daniel FINE, Randy GOODALL, Sharath HOSALI, Ryan MEDEMA, Lee HUDSON
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Patent number: 8480637Abstract: A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.Type: GrantFiled: November 13, 2009Date of Patent: July 9, 2013Assignees: The Board of Regents of the University of Texas System, The Ohio State University Research FoundationInventors: Mauro Ferrari, Xuewu Liu, Alessandro Grattoni, Daniel Fine, Randy Goodall, Sharath Hosali, Ryan Medema, Lee Hudson
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Publication number: 20130131629Abstract: Apparatus and methods of delivering a therapeutic agent using an implant comprising a nanochannel delivery device.Type: ApplicationFiled: May 19, 2011Publication date: May 23, 2013Applicant: The Board of Regents of the Unversity of Texas SystemInventors: Alessandro Grattoni, Aman P. Mann, Sharath Hosali, Randy Goodall, Lee Hudson
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Publication number: 20110288497Abstract: A nano-scale device and method of manufacturing and use. The nano-scale device may be used in-vivo and may comprise a fluid path with an inlet microchannel, an outlet microchannel, and a nanochannel. The fluid path comprises bio-robust material. In certain embodiments, the bio-robust material may be coated over a material that is not bio-robust.Type: ApplicationFiled: May 19, 2011Publication date: November 24, 2011Applicant: NANOMEDICAL SYSTEMS, INC.Inventors: Randy Goodall, Sharath Hosali
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Publication number: 20110201209Abstract: Methods and systems for planarization of a die-to-wafer integration. A planarization coating may be applied to the die-to-wafer assembly, and a planarization plate may be used in the planarization process. The planarization plate may include perforations configured to allow a portion of the planarization coating to extrude through the planarization plate.Type: ApplicationFiled: February 17, 2010Publication date: August 18, 2011Inventors: Sharath Hosali, Gregory Smith, Larry Smith