Patents by Inventor Sharmila ADHIKARI

Sharmila ADHIKARI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND METHODS FOR TREATING MALARIA
    Publication number: 20240166637
    Abstract: The present invention is related to the development of novel compounds and methods for the treatment and/or prevention of malaria. The compounds prevent the formation by the malaria parasite of the plasmodium surface anion channel (PSAC) on the surface of the host cell. The compounds and methods described herein are effective against infection by a wide variety of Plasmodia strains known as the causative agent of malaria.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 23, 2024
    Applicants: Microbiotix, Inc., The United States Of America As Represented By The Secretary, Department of Health and Human Service
    Inventors: Samanthi L. Waidyarachchi, Son T. Nguyen, Xiaoyuan Ding, Sharmila Adhikari, John D. Williams, Norton P. Peet, Zachary D. Aron, Sanjay A. Desai, Michelle M. Butler
  • ATG7 inhibitors and the uses thereof
    Patent number: 10865208
    Abstract: Disclosed are chemical entities which are compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, and Ra have the values described herein. Chemical entities according to the disclosure can be useful as inhibitors of ATG7. Further provided are pharmaceutical compositions comprising a chemical entity of the disclosure and methods of using the compositions in the treatment of cancer.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: December 15, 2020
    Assignee: MILLENNIUM PHARMACEUTICALS, INC.
    Inventors: Sharmila Adhikari, Emily Frances Calderwood, Dylan Bradley England, Alexandra E. Gould, Sean J. Harrison, Shih-Chung Huang, Liting Ma
  • ATG7 INHIBITORS AND THE USES THEREOF
    Publication number: 20190382406
    Abstract: Disclosed are chemical entities which are compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, and Ra have the values described herein. Chemical entities according to the disclosure can be useful as inhibitors of ATG7. Further provided are pharmaceutical compositions comprising a chemical entity of the disclosure and methods of using the compositions in the treatment of cancer.
    Type: Application
    Filed: November 10, 2017
    Publication date: December 19, 2019
    Inventors: Sharmila ADHIKARI, Emily Frances CALDERWOOD, Dylan Bradley ENGLAND, Alexandra E. GOULD, Sean J. HARRISON, Shih-Chung HUANG, Liting MA