Patents by Inventor Sharon Avhar-Maydan

Sharon Avhar-Maydan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for the preparation and purification of gabapentin enacarbil
    Patent number: 8283487
    Abstract: Gabapentin enacarbil was prepared and purified from intermediates such as 1-haloalkyl carbamate or carbonate and diacid acetal skeleton. For example, a 1-haloalkyl carbonate or carbamate was prepared by combining a C1 to C10 alcohol or C1 to C10 primary amine, a solvent selected from the group consisting of: acetonitrile, C3 to C7 ketone, C5 to C10 ether, C2 to C7 ester, C5 to C10 hydrocarbon and a combination thereof; a 1-haloalkyl haloformate of the following formula: wherein each X is independently selected from Br, I, or Cl; R1 is alkyl or H; and a C6 to C21 tertiary amine.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: October 9, 2012
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Elena Ben Moha-Lerman, Tamar Nidam, Meital Cohen, Sharon Avhar-Maydan, Anna Balanov
  • Preparation of Retapamulin via its Pleuromutilin-thiol precursor
    Publication number: 20100184987
    Abstract: Provided are processes for preparation of Retapamulin via its pleuromutilin-thiol precursor.
    Type: Application
    Filed: November 12, 2009
    Publication date: July 22, 2010
    Inventors: Nimer Jaber, Lilach Hedvati, Eyal Gilboa, Sharon Avhar-Maydan
  • PROCESSES FOR THE PREPARATION AND PURIFICATION OF GABAPENTIN ENACARBIL
    Publication number: 20100160665
    Abstract: Gabapentin enacarbil was prepared and purified from intermediates such as 1-haloalkyl carbamate or carbonate and diacid acetal skeleton. For example, a 1-haloalkyl carbonate or carbamate was prepared by combining a C1 to C10 alcohol or C1 to C10 primary amine, a solvent selected from the group consisting of: acetonitrile, C3 to C7 ketone, C5 to C10 ether, C2 to C7 ester, C5 to C10 hydrocarbon and a combination thereof; a 1-haloalkyl haloformate of the following formula: wherein each X is independently selected from Br, I, or Cl; R1 is alkyl or H; and a C6 to C21 tertiary amine.
    Type: Application
    Filed: November 26, 2009
    Publication date: June 24, 2010
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD.
    Inventors: Elena Ben Moha-Lerman, Tamar Nidam, Meital Cohen, Sharon Avhar-Maydan, Anna Balanov
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Patent number: 7687642
    Abstract: Provided are crystalline forms of fluvastatin sodium and processes for their preparation.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: March 30, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Publication number: 20090209611
    Abstract: Provided are crystalline forms of fluvastatin sodium and processes for their preparation.
    Type: Application
    Filed: March 25, 2009
    Publication date: August 20, 2009
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • Crystal forms of Cinacalcet HCI and processes for their preparation
    Patent number: 7563930
    Abstract: Provided are crystalline forms of Cinacalet HCl and processes for their preparation.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: July 21, 2009
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Shlomit Wizel, Revital Lifshitz-Liron, Sharon Avhar-Maydan
  • Process for the preparation of Retapamulin and its intermediates
    Publication number: 20090149655
    Abstract: Processes for preparing tropine derivatives of the following Formula B are provided where LG represents a leaving group. The tropine derivatives may be used to prepare Retapamulin, preferably in substantially pure form.
    Type: Application
    Filed: December 5, 2008
    Publication date: June 11, 2009
    Inventors: Lilach Hedvati, Eyal Gilboa, Sharon Avhar-Maydan, Sharona Shachan-Tov
  • Amorphous and crystalline forms of ibandronate disodium
    Publication number: 20090118239
    Abstract: Provided are amorphous and crystalline forms of ibandronate disodium, as well as processes for the preparation thereof.
    Type: Application
    Filed: May 15, 2008
    Publication date: May 7, 2009
    Inventors: Sharon Avhar-Maydan, Claude Singer, Tamas Koltai
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Publication number: 20090118518
    Abstract: Provided are crystalline forms of fluvastatin sodium and processes for their preparation.
    Type: Application
    Filed: April 30, 2008
    Publication date: May 7, 2009
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • Crystalline forms of ibandronate sodium
    Publication number: 20090042839
    Abstract: Provided are crystalline forms of ibandronate sodium, as well as processes for the preparation thereof.
    Type: Application
    Filed: May 15, 2008
    Publication date: February 12, 2009
    Inventors: Sharon Avhar-Maydan, Claude Singer, Tamas Koltai, Alexandr Jegorov
  • Crystalline forms of atorvastatin
    Publication number: 20090018182
    Abstract: Novel forms of atorvastatin hemi-calcium have been prepared and characterized. These novel forms are particularly useful in pharmaceutical compositions.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 15, 2009
    Inventors: Sigalit Levi, Revital Lifshitz-Liron, Sharon Avhar-Maydan
  • Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof
    Patent number: 7462738
    Abstract: Provided are processes for the synthesis of R-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid and salts thereof, intermediates in the synthesis of S-pregabalin.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: December 9, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Lilach Hedvati, Eyal Gilboa, Sharon Avhar-Maydan
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Patent number: 7414140
    Abstract: Provided are polymorphic forms of fluvastatin sodium and processes for their preparation.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 19, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • Fluvastatin sodium crystal forms, processes for preparing them, compositions containing them and methods of using them
    Publication number: 20080146817
    Abstract: Provided are crystalline forms of fluvastatin sodium and processes for their preparation.
    Type: Application
    Filed: January 29, 2007
    Publication date: June 19, 2008
    Inventors: Revital Lifshitz-Liron, Tamas Koltai, Judith Aronhime, Nurit Perlman, Sharon Avhar-Maydan
  • Amorphous cinacalcet hydrochloride and preparation thereof
    Patent number: 7368606
    Abstract: Provided is amorphous cinacalcet hydrochloride, processes for the preparation thereof, and pharmaceutical compositions therewith.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: May 6, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Revital Lifshitz-Liron, Michael Pinchasov, Shlomit Wizel, Sharon Avhar-Maydan
  • Crystalline forms of ibandronic acid and processes for preparation thereof
    Publication number: 20080009466
    Abstract: The invention relates to solid crystalline forms of ibandronic acid, pharmaceutical formulations thereof, and methods of treatment therewith.
    Type: Application
    Filed: April 25, 2007
    Publication date: January 10, 2008
    Inventors: Sharon Avhar-Maydan, Eyal Gilboa, Tamas Koltai, Revital Lifshitz-Liron
  • Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof
    Publication number: 20070293694
    Abstract: Provided are processes for the synthesis of R-(+)-3-(carbamoylmethyl)-5-methylhexanoic acid and salts thereof, intermediates in the synthesis of S-pregabalin.
    Type: Application
    Filed: May 24, 2007
    Publication date: December 20, 2007
    Inventors: Lilach Hedvati, Eyal Gilboa, Sharon Avhar-Maydan
  • Crystal forms of cinacalcet HCI and processes for their preparation
    Publication number: 20070185211
    Abstract: Provided are crystalline forms of cinacalcet HCl and processes for their preparation.
    Type: Application
    Filed: November 22, 2006
    Publication date: August 9, 2007
    Inventors: Shlomit Wizel, Revital Lifshitz-Liron, Sharon Avhar-Maydan
  • Process for preparing Cinacalcet hydrochloride
    Patent number: 7250533
    Abstract: Processes for preparing cinacalcet are provided.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: July 31, 2007
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Revital Lifshitz-Liron, Amihai Eisenstadt, Shlomit Wizel, Sharon Avhar-Maydan, Yuriy Raizi, Revital Ramaty
  • Processes for preparing cinacalcet hydrochloride crystal Form I
    Patent number: 7247751
    Abstract: The invention provides processes for the preparation of cinacalcet hydrochloride crystalline Form I.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: July 24, 2007
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Revital Lifshitz-Liron, Sharon Avhar-Maydan