Patents by Inventor Sharon Edmiston

Sharon Edmiston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of ITK inhibitors for the treatment of cancer
    Patent number: 9649313
    Abstract: This invention relates generally to the use of ITK (IL-2 inducible T-cell kinase) inhibitors for the treatment of patients who have melanoma or other solid tumors. Applicants demonstrate that ITK lentiviral small hairpin RNA knockdowns and a small molecule inhibitor can each decrease the proliferation and migration of melanoma cell lines and a small molecule inhibitor can be used to inhibit the growth of melanomas in vivo.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: May 16, 2017
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Nancy Thomas, Kathleen Dorsey, Sharon Edmiston, Pamela Groben, Craig Carson
  • USE OF ITK INHIBITORS FOR THE TREATMENT OF CANCER
    Publication number: 20160000788
    Abstract: This invention relates generally to the use of ITK (IL-2 inducible T-cell kinase) inhibitors for the treatment of patients who have melanoma or other solid tumors. Applicants demonstrate that ITK lentiviral small hairpin RNA knockdowns and a small molecule inhibitor can each decrease the proliferation and migration of melanoma cell lines and a small molecule inhibitor can be used to inhibit the growth of melanomas in vivo.
    Type: Application
    Filed: November 26, 2013
    Publication date: January 7, 2016
    Inventors: Nancy Thomas, Kathleen Dorsey, Sharon Edmiston, Pamela Groben, Craig Carson
  • METHODS AND KITS FOR DETECTING MELANOMA
    Publication number: 20150376717
    Abstract: This invention is directed to a method for detecting melanoma in a tissue sample by measuring a level of methylation of one or more regulatory elements differentially methylated in melanoma and benign nevi. The invention provides methods for detecting melanoma, related kits, and methods of screening for compounds to prevent or treat melanoma.
    Type: Application
    Filed: July 1, 2015
    Publication date: December 31, 2015
    Inventors: Nancy Thomas, Kathleen Dorsey, Sharon Edmiston, Pamela Groben
  • METHODS AND KITS FOR DETECTING MELANOMA
    Publication number: 20130237445
    Abstract: This invention is directed to a method for detecting melanoma in a tissue sample by measuring a level of methylation of one or more regulatory elements differentially methylated in melanoma and benign nevi. The invention provides methods for detecting melanoma, related kits, and methods of screening for compounds to prevent or treat melanoma.
    Type: Application
    Filed: September 13, 2011
    Publication date: September 12, 2013
    Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Nancy Thomas, Kathleen Dorsey, Sharon Edmiston, Pamela Groben