Patents by Inventor Sharon Fitzhenry

Sharon Fitzhenry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of nitroalcohol diastereomers
    Publication number: 20030040644
    Abstract: The present invention relates to a method of preparing a 1-nitro-3-substituted-3-amino-2-propanol diastereomer represented by Structural Formula I: 1
    Type: Application
    Filed: July 3, 2002
    Publication date: February 27, 2003
    Applicant: Pharm-Eco Laboratories, Inc.
    Inventors: Richard L. Gabriel, Adel M. Moussa, Sharon Fitzhenry, Changhua Liu, David A. Swanson, Brittany Le, Salah Zahr, Yesh P. Sachdeva, Jurjus Jurayj
  • Synthesis of nitroalcohol diastereomers
    Patent number: 6462221
    Abstract: The present invention relates to a method of preparing a 1-nitro-3-substituted-3-amino-2-propanol diastereomer represented by Structural Formula I: In Structural Formula I, R is an amine protecting group, and R1 is an amino acid side-chain, a protected amino acid side-chain, a substituted or unsubstituted aliphatic group, a substituted or unsubstituted aromatic group, a substituted or unsubstituted heteroaromatic group, a substituted or unsubstituted aralkyl or a substituted or unsubstituted heteroaralkyl group. The method involves contacting a 1-nitro-3-substituted-3-amino-2-propanone with a reducing agent to form a mixture of 1-nitro-3-substituted-3-amino-2-propanol diastereomers. The 1-nitro-3-substituted-3-amino-2-propanol diastereomers are then separated by simulated moving bed chromatography to obtain one or more 1-nitro-3-substituted-3-amino-2-propanol diastereomer.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: October 8, 2002
    Assignee: Pharm-Eco Laboratories, Inc.
    Inventors: Richard L. Gabriel, Adel M. Moussa, Sharon Fitzhenry, Changhua Liu, David A. Swanson, Brittany La, Salah Zahr, Yesh P. Sachdeva, Jurjus Jurayj