Patents by Inventor Sharon Gerecht-Nir

Sharon Gerecht-Nir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of dynamically culturing embryonic stem cells
    Patent number: 7947499
    Abstract: The present invention is of a method of dynamically generating human embryoid bodies which can be used for generating lineage specific cells and cell lines. Specifically, the present invention can be used to generate ESC-differentiated cells for cell-replacement therapy.
    Type: Grant
    Filed: November 30, 2003
    Date of Patent: May 24, 2011
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
  • METHOD OF DYNAMICALLY CULTURING EMBRYONIC STEM CELLS
    Publication number: 20110027887
    Abstract: The present invention is of a method of dynamically generating human embryoid bodies which can be used for generating lineage specific cells and cell lines. Specifically, the present invention can be used to generate ESC-differentiated cells for cell-replacement therapy.
    Type: Application
    Filed: October 18, 2010
    Publication date: February 3, 2011
    Applicant: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: SHARON GERECHT-NIR, JOSEPH ITSKOVITZ-ELDOR
  • FORMATION OF VASCULAR NETWORKS USING EMBRYONIC STEM CELLS
    Publication number: 20100233132
    Abstract: In various aspects, provided are methods for providing CD34+ cells from embryoid bodies and stimulating these cells to give rise to endothelial-like and/or smooth muscle-like cells. In various embodiments are provided methods that produce endothelial-like and/or smooth muscle-like cells that have functionality and/or preserved genetic integrity. In various aspects, provided are tissue engineering constructs comprising endothelial-like and/or smooth muscle-like cells produced according to a method the present inventions.
    Type: Application
    Filed: May 25, 2007
    Publication date: September 16, 2010
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Lino da Silva Ferreira, Sharon Gerecht-Nir, Robert S. Langer, Gordana V. Vunjak-Novakovic
  • Generating vascular smooth muscle cells in vitro from ES cells
    Publication number: 20080194023
    Abstract: A simplified and inexpensive method for the in-vitro identification, isolation and culture of human vasculogenic progenitor cells is provided. The method and the progenitor cells provided herein can be used for in-vitro vascular engineering, treatment of congenital and acquired vascular and hematological abnormalities, for evaluation and development of drugs affecting vasculo- and angiogenic processes, and for further investigation into tissue differentiation and development.
    Type: Application
    Filed: December 4, 2007
    Publication date: August 14, 2008
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
  • Generating vascular smooth muscle cells in vitro from ES cells
    Patent number: 7354763
    Abstract: A simplified and inexpensive method for the in-vitro identification, isolation and culture of human vasculogenic progenitor cells is provided. The method and the progenitor cells provided herein can be used for in-vitro vascular engineering, treatment of congenital and acquired vascular and hematological abnormalities, for evaluation and development of drugs affecting vasculo- and angiogenic processes, and for further investigation into tissue differentiation and development.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: April 8, 2008
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
  • Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells
    Patent number: 7247477
    Abstract: There is provided a simplified and inexpensive method for the in-vitro identification, isolation and culture of human vasculogenic progenitor cells. The method and the progenitor cells isolated thereby can be used for in-vitro vascular engineering, treatment of congenital and acquired vascular and hematological abnormalities, for evaluation and development of drugs affecting vasculo- and angiogenic processes, and for further investigation into tissue differentiation and development.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: July 24, 2007
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Joseph Itskovitz-Eldor, Sharon Gerecht-Nir
  • Propagation of undifferentiated embryonic stem cells in hyaluronic acid hydrogel
    Publication number: 20070122392
    Abstract: Embryonic stem cells are propagated in a hyaluronic acid.
    Type: Application
    Filed: June 22, 2006
    Publication date: May 31, 2007
    Inventors: Sharon Gerecht-Nir, Jason Burdick, Gordana Vunjak-Novakovic, Robert Langer
  • Method of dynamically culturing embryonic stem cells
    Publication number: 20060148078
    Abstract: he present invention is of a method of dynamically generating human embryoid bodies which can be used for generating lineage specific cells and cell lines. Specifically, the present invention can be used to generate ESC-differentiated cells for cell-replacement therapy.
    Type: Application
    Filed: November 30, 2003
    Publication date: July 6, 2006
    Inventors: Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
  • Novel methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells
    Publication number: 20050112106
    Abstract: A simplified and inexpensive method for the in-vitro identification, isolation and culture of human vasculogenic progenitor cells is provided. The method and the progenitor cells provided herein can be used for in-vitro vascular engineering, treatment of congenital and acquired vascular and hematological abnormalities, for evaluation and development of drugs affecting vasculo- and angiogenic processes, and for further investigation into tissue differentiation and development.
    Type: Application
    Filed: October 14, 2004
    Publication date: May 26, 2005
    Inventors: Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
  • Novel methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells
    Publication number: 20030194802
    Abstract: There is provided a simplified and inexpensive method for the in-vitro identification, isolation and culture of human vasculogenic progenitor cells. The method and the progenitor cells isolated thereby can be used for in-vitro vascular engineering, treatment of congenital and acquired vascular and hematological abnormalities, for evaluation and development of drugs affecting vasculo- and angiogenic processes, and for further investigation into tissue differentiation and development.
    Type: Application
    Filed: August 5, 2002
    Publication date: October 16, 2003
    Applicant: Technion Research and Development Foundation Ltd.
    Inventors: Joseph Itskovitz-Eldor, Sharon Gerecht-Nir