Patents by Inventor Sharon L. Malmstrom

Sharon L. Malmstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and apparatus for detection and discrimination of multiple analytes using flourescent technology
    Patent number: 5861256
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are rapid, accurate, and convenient enough for routine use in a clinical laboratory. In particular, the present invention provides methods and apparatus for permitting multiple PCR-amplified target nucleic acid sequence hybrids within a single sample, labeled with different fluorescent dyes, to be spectrally distinguished using the read-out data directly from a fluorescence reader instrument.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: January 19, 1999
    Assignee: Gull Laboratories
    Inventors: Michael J. Glass, Jana Coombs, Sharon L. Malmstrom, Linxian Wu
  • Methods and apparatus for preparing, amplifying, and discriminating multiple analytes
    Patent number: 5846783
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are simple, user-friendly, cost-effective and fast. In particular, it is preferred that the overall time for sample preparation, nucleic acid sequence amplification, and nucleic acid sequence differentiation be about 5 hours or less.
    Type: Grant
    Filed: August 6, 1996
    Date of Patent: December 8, 1998
    Assignee: Gull Laboratories
    Inventors: Linxian Wu, Jana Coombs, Sharon L. Malmstrom, Michael J. Glass
  • Specific oligonucleotide primer pairs and probes for discriminating specific analytes
    Patent number: 5756701
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are simple, user-friendly, cost-effective and fast. In particular, it is preferred that the overall time for sample preparation, nucleic acid sequence amplification, and nucleic acid sequence differentiation be about 5 hours or less.
    Type: Grant
    Filed: August 6, 1996
    Date of Patent: May 26, 1998
    Assignee: Gull Laboratories, Inc.
    Inventors: Linxian Wu, Jana Coombs, Sharon L. Malmstrom, Michael J. Glass
  • Methods and kits using inosine-containing probes for discriminating variant nucleic acid sequences
    Patent number: 5753444
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are simple, user-friendly, cost-effective and fast. In particular, it is preferred that the overall time for sample preparation, nucleic acid sequence amplification, and nucleic acid sequence differentiation be about 5 hours or less.
    Type: Grant
    Filed: August 7, 1996
    Date of Patent: May 19, 1998
    Assignee: Gull Laboratories, Inc.
    Inventors: Linxian Wu, Jana Coombs, Sharon L. Malmstrom, Michael J. Glass
  • Inosine-containing probes for detecting E.coli 0157:H7
    Patent number: 5738995
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are simple, user-friendly, cost-effective and fast. In particular, it is preferred that the overall time for sample preparation, nucleic acid sequence amplification, and nucleic acid sequence differentiation be about 5 hours or less.
    Type: Grant
    Filed: August 7, 1996
    Date of Patent: April 14, 1998
    Assignee: Gull Laboratories, Inc.
    Inventors: Linxian Wu, Jana Coombs, Sharon L. Malmstrom, Michael J. Glass
  • Methods for detection and discrimination of multiple analytes using fluorescent technology
    Patent number: 5723294
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are rapid, accurate, and convenient enough for routine use in a clinical laboratory. In particular, the present invention provides methods and apparatus for permitting multiple PCR-amplified target nucleic acid sequence hybrids within a single sample, labeled with different fluorescent dyes, to be spectrally distinguished using the read-out data directly from a fluorescence reader instrument.
    Type: Grant
    Filed: March 5, 1996
    Date of Patent: March 3, 1998
    Assignee: Gull Laboratories
    Inventors: Michael J. Glass, Jana Coombs, Sharon L. Malmstrom, Linxian Wu
  • Methods, kits and solutions for preparing sample material for nucleic acid amplification
    Patent number: 5612473
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are simple, user-friendly, cost-effective and fast. In particular, it is preferred that the overall time for sample preparation, nucleic acid sequence amplification, and nucleic acid sequence differentiation be about 5 hours or less.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: March 18, 1997
    Assignee: Gull Laboratories
    Inventors: Linxian Wu, Jana Coombs, Sharon L. Malmstrom, Michael J. Glass