Patents by Inventor Sharon Leigh GUFFY

Sharon Leigh GUFFY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPTIMIZED PROTEIN LINKERS AND METHODS OF USE
    Publication number: 20240002821
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based adenine base editors.
    Type: Application
    Filed: June 14, 2023
    Publication date: January 4, 2024
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • AGROBACTERIUM RHIZOGENES AND METHODS OF TRANSFORMING CELLS
    Publication number: 20230416765
    Abstract: Agrobacterium rhizogenes are described herein along with methods of transforming cells and methods of using Agrobacterium rhizogenes and/or transformed cells. Also described herein are plants, such as plants in the Rubus family, including a modified nucleic acid, optionally wherein the plants are transgene-free and include a modified nucleic acid.
    Type: Application
    Filed: November 23, 2021
    Publication date: December 28, 2023
    Inventors: Fang-Ming Lai, Eric Dean, Ming Cheng, Joel Reiner, Qingchun Shi, David Schwark, Sharon Leigh Guffy, Aaron Hummel
  • ENGINEERED PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20230383271
    Abstract: Described herein are engineered proteins and methods of use of such proteins. Also described herein are complexes, compositions, and systems including engineered proteins of the present invention, each of which may be used for modifying and/or editing a target nucleic acid. An engineered protein of the present invention may be an enzyme and/or may be an RNA-guided DNA-binding protein.
    Type: Application
    Filed: February 28, 2023
    Publication date: November 30, 2023
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • Optimized protein linkers and methods of use
    Patent number: 11718838
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based adenine base editors.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: August 8, 2023
    Assignee: Pairwise Plants Services. Inc.
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • Optimized protein linkers and methods of use
    Patent number: 11708568
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based cytosine base editors.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: July 25, 2023
    Assignee: Pairwise Plants Services, Inc.
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • ENGINEERED PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20220112473
    Abstract: Described herein are engineered proteins and methods of use of such proteins. Also described herein are complexes, compositions, and systems including engineered proteins of the present invention, each of which may be used for modifying or editing a target nucleic acid. An engineered protein of the present invention may be an enzyme and/or may be an RNA-guided DNA-binding protein.
    Type: Application
    Filed: August 27, 2021
    Publication date: April 14, 2022
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • OPTIMIZED PROTEIN LINKERS AND METHODS OF USE
    Publication number: 20220025346
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based adenine base editors.
    Type: Application
    Filed: July 21, 2021
    Publication date: January 27, 2022
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • OPTIMIZED PROTEIN LINKERS AND METHODS OF USE
    Publication number: 20210355466
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based cytosine base editors.
    Type: Application
    Filed: June 22, 2021
    Publication date: November 18, 2021
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • Optimized protein linkers and methods of use
    Patent number: 11072785
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based cytosine base editors.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: July 27, 2021
    Assignee: PAIRWISE PLANTS SERVICES, INC.
    Inventors: Sharon Leigh Guffy, Joseph Matthew Watts
  • RECRUITMENT METHODS AND COMPOUNDS, COMPOSITIONS AND SYSTEMS FOR RECRUITMENT
    Publication number: 20210171947
    Abstract: Described herein are recruitment methods and compounds, compositions, and systems for recruitment. Also described herein are methods and compositions for template editing of genomic DNA using Agrobacterium-derived T-DNA molecules and/or proteins.
    Type: Application
    Filed: December 6, 2020
    Publication date: June 10, 2021
    Inventors: Aaron Hummel, Shai Joshua Lawit, Jingyi Nie, Sabine Fräbel, Sharon Leigh Guffy
  • OPTIMIZED PROTEIN LINKERS AND METHODS OF USE
    Publication number: 20210017506
    Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based cytosine base editors.
    Type: Application
    Filed: July 17, 2020
    Publication date: January 21, 2021
    Inventors: Sharon Leigh GUFFY, Joseph Matthew WATTS