Abstract: The invention provides synergistic topical formulations comprising a cannabinoid; an extract from Paeonia lactiflora; and optionally allantoin. The invention further provides uses of these formulations in treating certain inflammatory diseases, wounds, scarring and the like. Examples of such diseases or conditions are arthritis, such as rheumatoid arthritis. Other examples are skin diseases or conditions, such as wound and consequent scarring.

Abstract: The present invention provides a topical formulation for use in a method of treating or preventing inflammatory skin conditions, said method comprising topically administrating a formulation comprising (i) cannabidiol and (ii) flavonolignans selected from silibinin, isosilibinin, silicristin, silidianin and combinations thereof. The invention further relates to a topical formulation comprising: cannabidiol; flavonolignans selected silibinin, isosilibinin, silicristin, silidianin and combinations thereof, the concentrations of these flavonolignans being calculated as silibinin; triterpenes selected from asiaticoside, madecassoside, asiatic acid, madecassic acid and combinations thereof.

Abstract: The present invention provides a topical formulation for use in a method of treating or preventing a sebaceous gland disorder selected from acne, seborrhea, rosacea, perioral dermatitis, corticosteroid-induced acneiform lesions and oily skin and/or for use in a method of inhibiting growth of riopionibacterium acnes, said method comprising topically administrating a formulation comprising (i) cannabidiol and (ii) triterpenes selected from asiaticoside, madecassoside, asiatic acid, madecassic acid and combinations thereof. The invention further relates to a topical formulation comprising: cannabidiol; triterpenes selected from asiaticoside, madecassoside, asiatic acid, madecassic acid and combinations thereof; flavonolignans selected silibinin, isosilibinin, silicristin, silidianin and combinations thereof, the concentrations of these flavonolignans being calculated as silibinin.

Abstract: The present invention provides a treatment of aging or UV-damaged skin comprising topically administrating a formulation comprising (i) cannabidiol and (ii) omega-3 fatty acid selected from eicosapentaenoic acid and docosahexaenoic acid and combinations thereof. The invention further relates to a topical formulation comprising: cannabidiol; and, omega-3 fatty acid selected from eicosapentaenoic acid and docosahexaenoic acid and combinations thereof.

Abstract: The application provides compositions, in particular dermatological compositions comprising extracts from argan tree for the treatment and prevention of dermatological conditions. More particularly, a composition comprising argan oil (AO), argan leaf extract (AL) and argan stem cells (ASC) is provided. Further provided is a method for reducing photoaging of the skin of a subject due to exposure to UV radiation which comprises applying the composition of the invention to the subject prior to exposure to UV radiation.

Abstract: Disclosed is a method of treating and/or preventing atopic dermatitis (AD) in a subject in need thereof, wherein the method comprises administering to the subject a therapeutically effective amount of a composition comprising a Sanguisorba officinalis root extract, an Ailanthus altissima bark extract, a Rheum palmatum root extract, a Cnidium monnieri fruit extract, a Scutellaria baicalensis root extract, and Glycyrrhiza glabra root extract thereby treating and/or preventing AD in the subject.

Abstract: The application provides compositions, in particular dermatological compositions comprising extracts from argan tree for the treatment and prevention of dermatological conditions. More particularly, a composition comprising argan oil (AO), argan leaf extract (AL) and argan stem cells (ASC) is provided. Further provided is a method for reducing photoaging of the skin of a subject due to exposure to UV radiation which comprises applying the composition of the invention to the subject prior to exposure to UV radiation.

Abstract: A composition comprising a Sanguisorbae officinalis plant extract and at least one additional plant extract selected from the group consisting of an Ailanthus altissima plant extract, a Galla rhois gallnut plant extract, a Glycyrrhiza Glabra plant extract, a Rheum palmatum plant extract and a Scutellaria baicalensis plant extract is disclosed. Compositions comprising Ailanthus altissima plant extract or Ailanthone are also disclosed.

Abstract: A topical composition comprising Rheum palmatum Root Extract, Cnidium monnieri Fruit Extract, Scutellaria baicalensis Root Extract, dipotassium glycyrrhizate, hyaluronic acid and a dermatologically acceptable carrier and use thereof for treating and/or preventing a chronic inflammatory skin disease or disorder or allergic skin conditions.

Abstract: A composition comprising a Sanguisorbae officinalis plant extract and at least one additional plant extract selected from the group consisting of an Ailanthus altissima plant extract, a Galla rhois gallnut plant extract, a Glycyrrhiza Glabra plant extract, a Rheum palmatum plant extract and a Scutellaria baicalensis plant extract is disclosed. Compositions comprising Ailanthus altissima plant extract or Ailanthone are also disclosed.