Patents by Inventor Sharon Tennant

Sharon Tennant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGENIC COMPOSITIONS
    Publication number: 20230414740
    Abstract: Technologies for the prevention and/or treatment of nosocomial infections.
    Type: Application
    Filed: February 3, 2023
    Publication date: December 28, 2023
    Inventors: Donna Ambrosino, Teresa J. Broering, Alan Cross, Richard Malley, Francis Michon, George Rainer Siber, Raphael Simon, Sharon Tennant
  • Immunogenic compositions
    Patent number: 11612647
    Abstract: Technologies for the prevention and/or treatment of nosocomial infections.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: March 28, 2023
    Assignees: University of Maryland, Baltimore, Affinivax, Inc.
    Inventors: Donna Ambrosino, Teresa J. Broering, Alan Cross, Richard Malley, Francis Michon, George Rainer Siber, Raphael Simon, Sharon Tennant
  • Live Attenuated Non-Transmissible Vaccines
    Publication number: 20220154135
    Abstract: The present invention provides genetically modified microorganisms with reduced transmissibility, wherein the microorganism has been genetically modified to express a single stranded binding protein (SSB) regulated by an arabinose responsive promoter, wherein the microorganism has a reduced growth capacity in the absence of arabinose.
    Type: Application
    Filed: November 22, 2021
    Publication date: May 19, 2022
    Inventors: Sharon Tennant, James Eugene Galen
  • IMMUNOGENIC COMPOSITIONS
    Publication number: 20220072118
    Abstract: Technologies for the prevention and/or treatment of nosocomial infections.
    Type: Application
    Filed: June 22, 2018
    Publication date: March 10, 2022
    Inventors: Donna Ambrosino, Teresa J. Broering, Alan Cross, Richard Malley, Francis Michon, George Rainer Siber, Raphael Simon, Sharon Tennant
  • Broad spectrum conjugate vaccine to prevent klebsiella pneumoniae and pseudomonas aeruginosa infections
    Patent number: 10556931
    Abstract: The present invention is drawn to conjugates and vaccine compositions comprising a Pseudomonas flagellin or an antigenic fragment or derivative thereof linked to one or more Klebsiella surface polysaccharide antigens, such as Klebsiella pneumoniae O polysaccharide from serovars O1, O2a, O2a,c, O3, O4, O5, O7, O8 and O12. The present invention also provides serovar reagent strains to produce the conjugates and vaccine compositions and methods of inducing an immune response with the conjugates and vaccine compositions.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: February 11, 2020
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Raphael Simon, Alan Cross, Sharon Tennant
  • BROAD SPECTRUM CONJUGATE VACCINE TO PREVENT KLEBSIELLA PNEUMONIAE AND PSEUDOMONAS AERUGINOSA INFECTIONS
    Publication number: 20180194812
    Abstract: The present invention is drawn to conjugates and vaccine compositions comprising a Pseudomonas flagellin or an antigenic fragment or derivative thereof linked to one or more Klebsiella surface polysaccharide antigens, such as Klebsiella pneumoniae O polysaccharide from serovars O1, O2a, O2a,c, O3, O4, O5, O7, O8 and O12. The present invention also provides serovar reagent strains to produce the conjugates and vaccine compositions and methods of inducing an immune response with the conjugates and vaccine compositions.
    Type: Application
    Filed: December 14, 2017
    Publication date: July 12, 2018
    Inventors: Raphael Simon, Alan Cross, Sharon Tennant
  • Broad spectrum conjugate vaccine to prevent and infections
    Patent number: 9988426
    Abstract: The present invention is drawn to conjugates and vaccine compositions comprising a Pseudomonas flagellin or an antigenic fragment or derivative thereof linked to one or more Klebsiella surface polysaccharide antigens, such as Klebsiella pneumoniae O polysaccharide from serovars O1, O2a, O2a,c, O3, O4, O5, O7, O8 and 012. The present invention also provides serovar reagent strains to produce the conjugates and vaccine compositions and methods of inducing an immune response with the conjugates and vaccine compositions.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: June 5, 2018
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Raphael Simon, Alan Cross, Sharon Tennant
  • BROAD SPECTRUM CONJUGATE VACCINE TO PREVENT KLEBSIELLA PNEUMONIAE AND PSEUDOMONAS AERUGINOSA INFECTIONS
    Publication number: 20170260240
    Abstract: The present invention is drawn to conjugates and vaccine compositions comprising a Pseudomonas flagellin or an antigenic fragment or derivative thereof linked to one or more Klebsiella surface polysaccharide antigens, such as Klebsiella pneumoniae O5 polysaccharide from serovars O1, O2a, O2a,c, O3, O4, O5, O7, O8 and 012. The present invention also provides serovar reagent strains to produce the conjugates and vaccine compositions and methods of inducing an immune response with the conjugates and vaccine compositions.
    Type: Application
    Filed: September 18, 2015
    Publication date: September 14, 2017
    Inventors: Raphael Simon, Alan Cross, Sharon Tennant
  • Broad spectrum vaccine against non-typhoidal
    Patent number: 9050283
    Abstract: The present invention is drawn to attenuated Salmonella serovar strains S. Typhimurium and S. Enteritidis, conjugate vaccines derived from these attenuated strains of S. Typhimurium and S. Enteritidis, comprising an O polysaccharide covalently linked to a flagellin protein, and methods for inducing an immune response in a subject comprising administering the attenuated strains and/or the conjugate vaccines of the invention.
    Type: Grant
    Filed: January 16, 2010
    Date of Patent: June 9, 2015
    Assignee: University of Maryland, Baltimore
    Inventors: Myron M. Levine, Raphael Simon, James Galen, Sharon Tennant
  • Broad Spectrum Vaccine Against Non-Typhoidal Salmonella
    Publication number: 20110274714
    Abstract: The present invention is drawn to attenuated Salmonella serovar strains S. Typhimurium and S. Enteritidis, conjugate vaccines derived from these attenuated strains of S. Typhimurium and S. Enteritidis, comprising an O polysaccharide covalently linked to a flagellin protein, and methods for inducing an immune response in a subject comprising administering the attenuated strains and/or the conjugate vaccines of the invention.
    Type: Application
    Filed: January 16, 2010
    Publication date: November 10, 2011
    Applicant: University of Maryland, Baltimore
    Inventors: Myron M. Levine, Raphael Simon, James Galen, Sharon Tennant