Abstract: There is disclosed herein a computer-implemented system and method of providing wellness detect and response (WDR) security services for an enterprise, including computing, for the enterprise, a quantitative user-centric security posture, wherein computing the quantitative user-centric security posture comprises calculating, for a user, a quantitative user risk profile according to a combination of user role, user privileges, user behavior, and digital assets assigned to a user and owned by the enterprise.

Abstract: Disclosed are compounds and compositions that modulate cannabinoid receptors, methods of modulating cannabinoid receptors, and methods of treating various disorders related to the modulation of cannabinoid receptors. This disclosure is directed to methods of treating cannabinoid dependence, neuropathy, inflammation, glaucoma, a neurodegenerative disorder, a motor function disorder, a gastrointestinal disorder, hypothermia, emesis, loss of appetite, or anorexia associated with AIDS.

Abstract: A computer-implemented method provides security services to an enterprise. The method computes, for a plurality of enterprise users, a plurality of user health scores based on respective protection statuses for a plurality of enterprise assets owned by respective users; computes, for the enterprise, an overall enterprise security status score based on the plurality of user health scores; graphically displays to an enterprise administrator the overall enterprise security status score; and presents to the enterprise administrator a plurality of action recommendations to improve the overall enterprise security status score.

Abstract: Novel cannabinoid ligands represented by the general formulas I, II, and III and methods for preparation and use within which one or more of a fluorescent ligand, nitroxide spin label, metal chelate, biotin moiety, or group with enhanced polarity may be incorporated. The compounds can bind to and modulate the cannabinoid CB1 and CB2 receptors and thereby considered specific ligands for these receptors. Some of the disclosed compounds that bind to cannabinoid CB1 and CB2 receptors can exhibit tight or irreversible binding characteristics for these receptors. Due to the presence of the imaging/diagnostic and/or therapeutic functional groups including fluorescent groups, nitroxide spin labels, metal chelates, biotin moieties, and groups with enhanced polarity, the disclosed compounds may be useful as imaging/diagnostic tools and/or therapeutic agents.

Abstract: The present invention provides compounds of Formula I?, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).

Abstract: The present invention relates to fused imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.

Abstract: Novel cannabinoid ligands represented by the general formulas I, II, and III and methods for preparation and use within which one or more of a fluorescent ligand, nitroxide spin label, metal chelate, biotin moiety, or group with enhanced polarity may be incorporated. The compounds can bind to and modulate the cannabinoid CB1 and CB2 receptors and thereby considered specific ligands for these receptors. Some of the disclosed compounds that bind to cannabinoid CB1 and CB2 receptors can exhibit tight or irreversible binding characteristics for these receptors. Due to the presence of the imaging/diagnostic and/or therapeutic functional groups including fluorescent groups, nitroxide spin labels, metal chelates, biotin moieties, and groups with enhanced polarity, the disclosed compounds may be useful as imaging/diagnostic tools and/or therapeutic agents.

Abstract: Disclosed are compounds and compositions that modulate cannabinoid receptors, methods of modulating cannabinoid receptors, and methods of treating various disorders related to the modulation of cannabinoid receptors. This disclosure is directed to methods of treating cannabinoid dependence, neuropathy, inflammation, glaucoma, a neurodegenerative disorder, a motor function disorder, a gastrointestinal disorder, hypothermia, emesis, loss of appetite, or anorexia associated with AIDS.

Abstract: Systems and methods for generating a blueprint for an enterprise is provided. The system obtains information pertaining to an enterprise from data sources, extracts entities from the information, and identifies relationships across the entities, performs conflict resolution check on the information received from the data sources based on pre-defined rules, identifies one or more missing links in the information. The system further computes a completeness score for the information based on at least one of the conflict resolution check and the missing links, and generates a blueprint of the information and the one or more entities for the enterprise. Authentic data sources are identified from the data sources based on at least one of assigned weight, and one or more instances of, and contribution by, the data sources in the information. The completeness score is computed based on the instances and contribution of the sources in the information.

Abstract: Methods and systems are presented for evaluating performance of a finite or infinite antenna array including a finite number of antennas. Typically, a model is generated for the antenna array, the model including an arbitrarily large antenna array with an arbitrarily large number of model antennas. Each model antenna has features defined by features of antennas of the finite or infinite antenna array. A unit cell is determined for the arbitrarily large antenna, and impedance matrices Zantenna and Zperiodic are computed, Zperiodic representing interactions among the unit cell and the other model antennas. From these matrices, the performance of the finite or infinite antenna array is assessed.

Abstract: A droplet coalescing filter cartridge is provided. The filter cartridge includes an outer filter tube and an inner filter tube disposed within the outer filter tube, and is configured to provide parallel filtration of a fluid flow. The filter includes a depth media configured to coalesce fine droplets or aerosols from an air flow. The filter cartridge is suitable for use in a coalescing filter assembly including the filter cartridge and a secondary filter element.

Abstract: Systems and methods for generating a blueprint for an enterprise is provided. The system obtains information pertaining to an enterprise from data sources, extracts entities from the information, and identifies relationships across the entities, performs conflict resolution check on the information received from the data sources based on pre-defined rules, identifies one or more missing links in the information. The system further computes a completeness score for the information based on at least one of the conflict resolution check and the missing links, and generates a blueprint of the information and the one or more entities for the enterprise. Authentic data sources are identified from the data sources based on at least one of assigned weight, and one or more instances of, and contribution by, the data sources in the information. The completeness score is computed based on the instances and contribution of the sources in the information.

Abstract: Methods and systems are presented for evaluating performance of a finite or infinite antenna array including a finite number of antennas. Typically, a model is generated for the antenna array, the model including an arbitrarily large antenna array with an arbitrarily large number of model antennas. Each model antenna has features defined by features of antennas of the finite or infinite antenna array. A unit cell is determined for the arbitrarily large antenna, and impedance matrices Zantenna and Zperiodic are computed, Zperiodic representing interactions among the unit cell and the other model antennas. From these matrices, the performance of the finite or infinite antenna array is assessed.