Patents by Inventor SHASHANK RAINA
SHASHANK RAINA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240115310Abstract: A method to treat a human patient including: advancing a catheter through a natural airway of the patient and positioning a distal portion of the catheter in the natural airway of a lung of the patient to a target region in the lung, injecting a conductive hypertonic saline solution having a concentration of at least 5% of sodium chloride by weight/volume from the distal portion of the catheter into the target region; delivering energy from the distal portion into the hypertonic saline solution in the target region, wherein the energy heats the hypertonic saline solution in the target region; ablating the target region with the heated conductive hypertonic saline solution, sensing electric impedance or electric conductivity of the target region during the delivery of the energy, and controlling the rate or a bolus of the hypertonic saline solution injected into the target region based on the electric impedance or the electric conductivity.Type: ApplicationFiled: October 16, 2023Publication date: April 11, 2024Inventors: Dorin Panescu, Shashank Raina, Simplicio Velilla, Mark Gelfand, Mark Leung
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Patent number: 11925409Abstract: An ablation catheter configured to ablate tissue in a lung of a patient including: a flexible shaft that advances endobronchially into an airway of the lung and has an outer diameter of 2.0 mm or less; an ablation electrode attached to a distal portion of the flexible shaft and to deliver radiofrequency (RF) electrical current to the tissue and conductively connectable to an RF electrical energy source external to the patient; wherein an outer diameter of an assembly of the flexible shaft and the ablation electrode is no greater than 2.0 mm; a liquid outlet on the distal portion and configured to be in fluid communication with a source of hypertonic saline solution; and a first occluder attached to the flexible shaft proximal to the ablation electrode and proximal to the liquid outlet, wherein the first occluder is configured to expand to occlude the airway.Type: GrantFiled: November 3, 2020Date of Patent: March 12, 2024Assignee: ZIDAN MEDICAL INC.Inventors: Dorin Panescu, Shashank Raina, Mark Gelfand, Mark Leung, Simplicio Velilla
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Publication number: 20230355300Abstract: A system for treatment of a target region of lung tissue including: a flow regulator configured to be interposed between a conductive fluid source and a conductive fluid outlet positionable at or in proximity of the target region of lung tissue, the flow regulator being further configured for controlling a flow rate or a bolus quantity of conductive fluid coming from the fluid source and delivered to the conductive fluid outlet; and a controller communicatively connectable with said flow regulator and with at least one sensor, with the at least one sensor being configured for detecting values taken by at least one control parameter representative of a physical property, wherein the physical property is one of temperature (T), pressure (p), electric impedance (Z), or electric conductivity (C) of material present at or in proximity of the target region of lung tissue.Type: ApplicationFiled: September 27, 2021Publication date: November 9, 2023Inventors: Dorin PANESCU, Shashank RAINA, Simplicio Aguilar VELILLA, Mark GELFAND, Mark LEUNG
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Publication number: 20230301711Abstract: A system for treatment of a target region of lung tissue including: a flow regulator configured to be interposed between a conductive fluid source and a conductive fluid outlet at a distal region of a catheter positioned in the target region and the conductive fluid outlet is positionable at or in proximity of the target region of lung tissue, wherein the flow regulator being further configured to control a flow rate or a bolus quantity of the conductive fluid coming from the fluid source and delivered through the conductive fluid outlet to the target region; an ablation electrode mounted to the distal region of the catheter; a controller configured to control the flow regulator, and configured to control power delivered from an ablation energy source to the ablation electrode, wherein the controller is configured to: receive one or more of the values of the control parameter; control the delivery of power from the ablation energy source to the ablation electrode; while the power is delivered to the ablationType: ApplicationFiled: August 16, 2021Publication date: September 28, 2023Inventors: Shashank RAINA, Shivkumar SABESAN, Mark GELFAND, Miriam TAIMISTO
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Patent number: 11701454Abstract: A medical device includes a body defining an exterior surface, and a coating including a therapeutic agent-containing nanoparticle disposed on the exterior surface of the medical device. The nanoparticle may include a brush-arm star polymer. The therapeutic agent may be paclitaxel.Type: GrantFiled: August 14, 2020Date of Patent: July 18, 2023Assignee: Medtronic Vascular, Inc.Inventors: Shashank Raina, John Kantor, Susan Peterson
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Publication number: 20210068895Abstract: An ablation catheter configured to ablate tissue in a lung of a patient including: a flexible shaft that advances endobronchially into an airway of the lung and has an outer diameter of 2.0 mm or less; an ablation electrode attached to a distal portion of the flexible shaft and to deliver radiofrequency (RF) electrical current to the tissue and conductively connectable to an RF electrical energy source external to the patient; wherein an outer diameter of an assembly of the flexible shaft and the ablation electrode is no greater than 2.0 mm; a liquid outlet on the distal portion and configured to be in fluid communication with a source of hypertonic saline solution; and a first occluder attached to the flexible shaft proximal to the ablation electrode and proximal to the liquid outlet, wherein the first occluder is configured to expand to occlude the airway.Type: ApplicationFiled: November 3, 2020Publication date: March 11, 2021Inventors: Dorin PANESCU, Shashank Raina, Mark Gelfand, Mark Leung, Simplicio Velilla
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Publication number: 20210007796Abstract: A system for treatment of a target region of lung tissue including: a flow regulator configured to be interposed between a conductive fluid source and a conductive fluid outlet positionable at or in proximity of the target region of lung tissue, the flow regulator being further configured for controlling a flow rate or a bolus quantity of conductive fluid coming from the fluid source and delivered to the conductive fluid outlet; and a controller communicatively connectable with said flow regulator and with at least one sensor, with the at least one sensor being configured for detecting values taken by at least one control parameter representative of a physical property, wherein the physical property is one of temperature (T), pressure (p), electric impedance (Z), or electric conductivity (C) of material present at or in proximity of the target region of lung tissue.Type: ApplicationFiled: July 24, 2019Publication date: January 14, 2021Inventors: Dorin PANESCU, Shashank Raina, Simplicio Velilla, Mark Gelfand, Mark Leung
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Publication number: 20200368400Abstract: A medical device includes a body defining an exterior surface, and a coating including a therapeutic agent-containing nanoparticle disposed on the exterior surface of the medical device. The nanoparticle may include a brush-arm star polymer. The therapeutic agent may be paclitaxel.Type: ApplicationFiled: August 14, 2020Publication date: November 26, 2020Inventors: Shashank Raina, John Kantor, Susan Peterson
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Patent number: 10842560Abstract: An ablation catheter configured to ablate tissue in a lung of a patient including: a flexible shaft that advances endobronchially into an airway of the lung and has an outer diameter of 2.0 mm or less; an ablation electrode attached to a distal portion of the flexible shaft and to deliver radiofrequency (RF) electrical current to the tissue and conductively connectable to an RF electrical energy source external to the patient; wherein an outer diameter of an assembly of the flexible shaft and the ablation electrode is no greater than 2.0 mm; a liquid outlet on the distal portion and configured to be in fluid communication with a source of hypertonic saline solution; and a first occluder attached to the flexible shaft proximal to the ablation electrode and proximal to the liquid outlet, wherein the first occluder is configured to expand to occlude the airway.Type: GrantFiled: July 24, 2019Date of Patent: November 24, 2020Assignee: Zidan Medical Inc.Inventors: Dorin Panescu, Shashank Raina, Mark Gelfand, Mark Leung, Simplicio Velilla
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Patent number: 10772993Abstract: A medical device includes a body defining an exterior surface, and a coating including a therapeutic agent-containing nanoparticle disposed on the exterior surface of the medical device. The nanoparticle may include a brush-arm star polymer. The therapeutic agent may be paclitaxel.Type: GrantFiled: February 21, 2018Date of Patent: September 15, 2020Assignee: Medtronic Vascular, Inc.Inventors: Shashank Raina, John Kantor, Susan Peterson
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Patent number: 10668255Abstract: A medical device includes a catheter, an expandable balloon on the distal portion of the catheter, and a sheath that is configured to enclose and protect the expandable balloon. The sheath extends within a sheath lumen of the catheter and out from the catheter through a distal opening of the sheath lumen. When in a deployed configuration, the sheath extends proximally to enclose at least a portion of the expandable balloon. The sheath may be axially movable within the sheath lumen of the catheter to actuate from the deployed configuration to a retracted configuration. In moving to the retracted configuration, the sheath may expose the outer surface of the expandable balloon.Type: GrantFiled: January 19, 2018Date of Patent: June 2, 2020Assignee: MEDTRONIC VASCULAR, INC.Inventors: John Kantor, Claudio Silvestro, Shashank Raina
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Publication number: 20190343581Abstract: An ablation catheter configured to ablate tissue in a lung of a patient including: a flexible shaft that advances endobronchially into an airway of the lung and has an outer diameter of 2.0 mm or less; an ablation electrode attached to a distal portion of the flexible shaft and to deliver radiofrequency (RF) electrical current to the tissue and conductively connectable to an RF electrical energy source external to the patient; wherein an outer diameter of an assembly of the flexible shaft and the ablation electrode is no greater than 2.0 mm; a liquid outlet on the distal portion and configured to be in fluid communication with a source of hypertonic saline solution; and a first occluder attached to the flexible shaft proximal to the ablation electrode and proximal to the liquid outlet, wherein the first occluder is configured to expand to occlude the airway.Type: ApplicationFiled: July 24, 2019Publication date: November 14, 2019Inventors: Dorin PANESCU, Shashank RAINA, Mark Gelfand, Mark LEUNG, Simplicio VELILLA
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Publication number: 20190224460Abstract: A medical device includes a catheter, an expandable balloon on the distal portion of the catheter, and a sheath that is configured to enclose and protect the expandable balloon. The sheath extends within a sheath lumen of the catheter and out from the catheter through a distal opening of the sheath lumen. When in a deployed configuration, the sheath extends proximally to enclose at least a portion of the expandable balloon. The sheath may be axially movable within the sheath lumen of the catheter to actuate from the deployed configuration to a retracted configuration. In moving to the retracted configuration, the sheath may expose the outer surface of the expandable balloon.Type: ApplicationFiled: January 19, 2018Publication date: July 25, 2019Inventors: John Kantor, Claudio Silvestro, Shashank Raina
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Publication number: 20180236139Abstract: A medical device includes a body defining an exterior surface, and a coating including a therapeutic agent-containing nanoparticle disposed on the exterior surface of the medical device. The nanoparticle may include a brush-arm star polymer. The therapeutic agent may be paclitaxel.Type: ApplicationFiled: February 21, 2018Publication date: August 23, 2018Inventors: SHASHANK RAINA, JOHN KANTOR, SUSAN PETERSON