Patents by Inventor Shashiprabha

Shashiprabha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (E)-2-(3-Cyano-4-isobutoxyphenyl)-N?-(substituted benzylidene)-4-methylthiazole-5-carbohydrazides as anti-tubercular agents
    Patent number: 12172973
    Abstract: Novel arylhydrazones derivatives, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The arylhydrazones derivative compounds are useful as anti-tubercular agents.
    Type: Grant
    Filed: October 6, 2023
    Date of Patent: December 24, 2024
    Assignee: KING FAISAL UNIVERSITY
    Inventors: Katharigatta N. Venugopala, Pran Kishore Deb, Melendran Pillay, Nefisath P., Mohamed A. Morsy, Shashiprabha S., Jagadeesh Prasad Dasappa, Rashmi Venugopala, Osama I. Alwassil
  • (E)-2-(3-cyano-4-isobutoxyphenyl)-n?-(substituted benzylidene)-4-methylthiazole-5-carbohydrazides as anti-tubercular agents
    Patent number: 12145915
    Abstract: Novel arylhydrazones derivatives, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The arylhydrazones derivative compounds are useful as anti-tubercular agents.
    Type: Grant
    Filed: December 22, 2023
    Date of Patent: November 19, 2024
    Assignee: KING FAISAL UNIVERSITY
    Inventors: Katharigatta N. Venugopala, Pran Kishore Deb, Melendran Pillay, Nefisath P, Mohamed A. Morsy, Shashiprabha S, Jagadeesh Prasad Dasappa, Rashmi Venugopala, Osama I. Alwassil
  • Oxoimidazolidine derivatives as anti-tubercular agents
    Patent number: 11981643
    Abstract: Novel oxoimidazolidine derivative compounds, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The oxoimidazolidine derivative compounds are useful as anti-tubercular agents.
    Type: Grant
    Filed: October 2, 2023
    Date of Patent: May 14, 2024
    Assignee: KING FAISAL UNIVERSITY
    Inventors: Katharigatta N. Venugopala, Pran Kishore Deb, Melendran Pillay, Nefisath P, Mohamed A. Morsy, Shashiprabha S, Jagadeesh Prasad Dasappa, Rashmi Venugopala
  • Benzylidene derivatives of fenobam as anti-inflammatory agents
    Patent number: 11905279
    Abstract: Benzylidene derivatives of fenobam compounds, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The benzylidene derivatives of fenobam, identified as COX-1 and COX-2 inhibitors, are useful as anti-inflammatory agents.
    Type: Grant
    Filed: October 13, 2023
    Date of Patent: February 20, 2024
    Assignee: KING FAISAL UNIVERSITY
    Inventors: Katharigatta N. Venugopala, Pran Kishore Deb, Wafa Hourani, Nefisath P, Mohamed A. Morsy, Shashiprabha S, Jagadeesh Prasad Dasappa, Rashmi Venugopala, Raghu Prasad Mailavaram
  • 3-(5-methyl-2-oxo-l, 3-dioxol-4-yl) methyloxy-2-trans-[(4-chloro phenyl) cyclohexyl][1,4]naphthaquinone-atovaquone prodrug
    Patent number: 9169232
    Abstract: The present invention relates to atovaquone prodrug compound of formula (I). Accordingly, present invention provides a process involving condensation of Atovaquone (II) with 5-methyl-4-chloromethyl dioxalone (III) in suitable solvent system and optionally followed by distillation and crystallization to provide Atovaquone prodrug compound of formula (I) in high yields, purity, and suitable for large-scale manufacture.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: October 27, 2015
    Assignee: Alkem Laboratories Limited
    Inventors: Sanjay Sukumar Saralaya, Akshaya Kunjyannaya, Shashiprabha, Shridhara Kanakamajalu, Kothapalli Sundarraja Rao, Kuppuswamy Nagarajan
  • 3-(5-METHYL-2-OXO-L, 3-DIOXOL-4-YL) METHYLOXY-2- TRANS-[(4-CHLORO PHENYL) CYCLOHEXYL][1,4]NAPHTHAQUINONE-ATOVAQUONE PRODRUG
    Publication number: 20140343297
    Abstract: The present invention relates to atovaquone prodrug compound of formula (I). Accordingly, present invention provides a process involving condensation of Atovaquone (II) with 5-methyl-4-chloromethyl dioxalone (III) in suitable solvent system and optionally followed by distillation and crystallization to provide Atovaquone prodrug compound of formula (I) in high yields, purity, and suitable for large-scale manufacture.
    Type: Application
    Filed: September 14, 2012
    Publication date: November 20, 2014
    Applicant: ALKEM LABORATORIES LTD.
    Inventors: Sanjay Sukumar Saralaya, Akshaya Kunjyannaya, (none) Shashiprabha, Shridhara Kanakamajalu, Kothapalli Sundarraja Rao, Kuppuswamy Nagarajan
  • Process for the preparation of ziprasidone
    Patent number: 8410268
    Abstract: The present invention relates to a process for preparing Ziprasidone of formula I, or a pharmaceutically acceptable salt or a solvate or a hydrate thereof; comprising the steps of reacting 1-(1,2-benzisothiazol-3-yl) piperazine of formula II or its salt: with 5-(2-haloethyl)-6-chloro-oxindole of formula III: wherein X is leaving groups like fluoro, chloro, bromo, iodo or sulphonyl; in the presence of a dispersing agent and a base in a solvent to form ziprasidone of formula I; and optionally converting the ziprasidone formed into a pharmaceutically acceptable acid addition salts of ziprasidone; or a solvate or a hydrate thereof.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: April 2, 2013
    Assignee: Alkem Laboratories Limited
    Inventors: Shashiprabha, Kanakamajalu Shridhara, Debkiron Mukherjee, Padmashree Badraje, K Sundarraja Rao, Kuppuswamy Nagarajan
  • Preparation of naphthoquinone compounds using 2,3-dihalonaphthoquinone
    Patent number: 8283499
    Abstract: The present invention relates the use of 2,3-dihalonaphthoquinone compounds of Formula I wherein R1 and R2 are leaving groups like halogens selected from the group comprising Cl, Br, I and F and the R1 and R2 may be the same halogen or may contain different halogen groups, or sulphonyl groups, for making napthoquinone compounds of Formula IA wherein X is any aryl, heteroaryl, alkyl, cyclohexyl, substituted cylohexyl groups and the like.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: October 9, 2012
    Assignee: Alkem Laboratories Limited
    Inventors: Sanjay Sukumar Saralya, Shashikumar Hiriyalu Somashekar, Shashiprabha, Shridhara Kanakamajalu, Koottungalmadhom Ramaswamy Ranganathan, Veerasamy Ananthalakshmi, Govindarajalu Jeyaraman, Kothapalli Sundarraja Rao, Kuppuswamy Nagarajan
  • PREPARATION OF NAPHTHOQUINONE COMPOUNDS USING 2,3-DIHALONAPHTHOQUINONE
    Publication number: 20110004024
    Abstract: The present invention relates the use of 2,3-dihalonaphthoquinone compounds of Formula I wherein R1 and R2 are leaving groups like halogens selected from the group comprising Cl, Br, I and F and the R1 and R2 may be the same halogen or may contain different halogen groups, or sulphonyl groups, for making napthoquinone compounds of Formula IA wherein X is any aryl, heteroaryl, alkyl, cyclohexyl, substituted cylohexyl groups and the like.
    Type: Application
    Filed: March 6, 2009
    Publication date: January 6, 2011
    Applicant: ALKEM LABORATORIES LIMITED
    Inventors: Sanjay Sukumar Saralya, Shashikumar Hiriyalu Somashekar, Shashiprabha, Shridhara Kanakamajalu, Koottungalmadhom Ramaswamy Ranganathan, Veerasamy Ananthalakshmi, Govindarajalu Jeyaraman, Kothapalli Sundarraja Rao, Kuppuswamy Nagarajan
  • Process for the Preparation of Ziprasidone
    Publication number: 20110003995
    Abstract: The present invention relates to a process for preparing Ziprasidone of formula I, or a pharmaceutically acceptable salt or a solvate or a hydrate thereof; comprising the steps of reacting 1-(1,2-benzisothiazol-3-yl) piperazine of formula II or its salt: with 5-(2-haloethyl)-6-chloro-oxindole of formula III: wherein X is leaving groups like fluoro, chloro, bromo, iodo or sulphonyl; in the presence of a dispersing agent and a base in a solvent to form ziprasidone of formula I; and optionally converting the ziprasidone formed into a pharmaceutically acceptable acid addition salts of ziprasidone; or a solvate or a hydrate thereof.
    Type: Application
    Filed: March 9, 2009
    Publication date: January 6, 2011
    Applicant: ALKEM LABORATORIES LIMITED
    Inventors: N/A Shashiprabha, K. Shridhara, Debkiron Mukherjee, Padmashree Badraje, K. Sundarraja Rao, K. Nagarajan