Abstract: The present disclosure provides a modular instrument system for accessing a site within a patient's body, such as for example, to inject or remove material. In one exemplary embodiment, an access device is coupled to an adapter and power drilled into a site within a patient. Once the access device is in position, the adapter may be further attached to other instruments, or to an injection or extraction system. The adapter may accommodate various other connectors to make the instrument system compatible with a variety of other surgical instruments and tools.

Abstract: An instrument for navigating to a target area near a subchondral defect of a bone and associated methods are disclosed. The instrument can include a body portion having a patient specific surface defining a negative impression of a portion of a skin surface of a patient, and a targeting device coupled to the body portion, the targeting device including a rail and at least one device portal configured to guide a device into a subchondral region of the bone for treatment at the target area.

Abstract: Instruments and associated methods are disclosed for treating joints, and particularly bone tissue. In general, the embodiments relate to instruments and associated methods for the surgical treatment of a joint, and particularly to a subchondral bone defect at that joint region. More specifically, the embodiments relate to instruments that allow fast, easy, precise, and controllable subchondral delivery to, or removal of materials from, a bone joint being treated.

Abstract: The present disclosure provides a modular instrument system for accessing a site within a patient's body, such as for example, to inject or remove material. In one exemplary embodiment, an access device is coupled to an adapter and power drilled into a site within a patient. Once the access device is in position, the adapter may be further attached to other instruments, or to an injection or extraction system. The adapter may accommodate various other connectors to make the instrument system compatible with a variety of other surgical instruments and tools.

Abstract: One embodiment disclosed provides a guide instrument for controlling the depth and trajectory of a surgical access device into a bone.

Abstract: The present disclosure provides a modular instrument system for accessing a site within a patient's body, such as for example, to inject or remove material. In one exemplary embodiment, an access device is coupled to an adapter and power drilled into a site within a patient. Once the access device is in position, the adapter may be further attached to other instruments, or to an injection or extraction system. The adapter may accommodate various other connectors to make the instrument system compatible with a variety of other surgical instruments and tools.

Abstract: An instrument for navigating to a target area near a subchondral defect of a bone and associated methods are disclosed. The instrument can include a body portion having a patient specific surface defining a negative impression of a portion of a skin surface of a patient, and a targeting device coupled to the body portion, the targeting device including a rail and at least one device portal configured to guide a device into a subchondral region of the bone for treatment at the target area.

Abstract: A system and associated instruments for locating, and accurately and controllably delivering, a device to an area sufficiently near a bone defect using anatomical landmarks is provided. The instruments allow the surgeon to navigate to the area around the bone defect quickly and easily, while so facilitating proper insertion of the device. In some embodiments, the defect is located on a femur. Guide instruments having a plurality of device portals are also provided for use as standalone instruments or as accessories to the system. In addition, a protective guide sleeve is provided for the insert of small diameter devices.

Abstract: Devices, instruments and associated methods for the subchondral treatment of osteoarthritis in small joints are provided. In addition, a method for treating joint pain in small joints is provided. These small joints may be ankle, elbow or wrist joints. The methods may target one of many different access points having trajectories with a common focal point at or near the small joint. The instruments may limit access to areas within or near the small joint by providing predefined entry paths that avoid damage to surrounding tissues.

Abstract: Devices, instruments and associated methods for the subchondral treatment of osteoarthritis in small joints are provided. In addition, a method for treating joint pain in small joints is provided. These small joints may be ankle, elbow or wrist joints. The methods may target one of many different access points having trajectories with a common focal point at or near the small joint. The instruments may limit access to areas within or near the small joint by providing predefined entry paths that avoid damage to surrounding tissues.

Abstract: Navigation instruments and guides for targeting a subchondral region of bone and subchondral bone defects are provided. The instruments and guides may be used in reference to an anatomical landmark of a joint.

Abstract: Implantable devices for the surgical treatment of bone, and particularly to a bone defect at a joint region, and even more particularly at the subchondral bone level of the joint region, are disclosed. The implantable devices may be formed of a bone material, and configured to serve the dual functions of providing mechanical strength and structural integrity to the area to be treated, while also facilitating the dispersal of a flowable material in the same area. Associated delivery tools are also provided.

Abstract: An instrument for controlled delivery of a device to a target area near a defect of a bone is provided. The instrument comprises a guide frame having a plurality of device portals, each portal defining a trajectory. The guide frame further includes visual markers for aligning the guide frame to an anatomical landmark on the bone to be treated. The instrument also includes a holder for releasable attachment with the guide frame. Each device portal is configured to provide accurate and controlled delivery of the device to the target area. In one example, the markers are radiopaque, and are visualized through fluoroscopy. A method of using the instrument is also provided.

Abstract: Systems and methods for the treatment of a joint are provided. These systems and methods may also include a subchondral treatment of bone of the same joint. These joint treatment methods may be non-surgical or surgical. Also provided are devices and instruments associated with the methods.

Abstract: A coordinate mapping system is provided for locating a defect in a bone. The system comprises a positioning instrument for controlled delivery of a device to a target site, the instrument comprising a main body and a rail extending from the main body, the rail including a series of indicia corresponding to predefined grid lines, and a template configured to overlay an image of a bone having a defect at the target site, the template including a predefined grid for determining a set of coordinates to locate the target site using the positioning instrument. A method of accessing a target site near a defect in a bone using the radial coordinate mapping system is also provided.

Abstract: Instruments for treating bone defects of the joint, particularly at the subchondral level, such as bone marrow lesions or bone marrow edema, are provided. In particular, these instruments may be delivery instruments that comprise features to control the location to which they deliver injectable materials or other tools to the bone to be treated. Also provided is an injection instrument that delivers a treatment material to the bone defect and stimulates a natural healing response in the bone.

Abstract: Devices, instruments and associated methods for the subchondral treatment of osteoarthritis in small joints are provided. In addition, a method for treating joint pain in small joints is provided. These small joints may be ankle, elbow or wrist joints. The methods may target one of many different access points having trajectories with a common focal point at or near the small joint. The instruments may limit access to areas within or near the small joint by providing predefined entry paths that avoid damage to surrounding tissues.

Abstract: Devices and associated methods are disclosed for treating bone, and particularly bone tissue at the joints. Disclosed are implantable devices that can be used either alone or in combination with this augmentation or hardening material for the repair of bone defects and which are particularly suited for use at the joints, and even more particularly suited for use at the subchondral bone level.

Abstract: Instruments and associated methods are disclosed for treating joints, and particularly bone tissue. One of these instruments may be a positioning instrument for controlled delivery of a device to a target site of the bone tissue being treated. The positioning instrument may comprise an alignment guide having a device portal for insertion of a device therethrough. The positioning instrument may have an indicator probe having an extended arm, and a handle portion for maneuvering the positioning instrument. Another instrument may be a device for placement through the device portal of the alignment guide and to the target site. The device may comprise an implant insertion tool, an injection catheter, a cavity creation tool such as a bone drill, for example, or the device may be an implantable device.

Abstract: One embodiment disclosed provides a guide instrument for controlling the depth and trajectory of a surgical access device into a bone.