Patents by Inventor Shauna Ebanks

Shauna Ebanks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Treating Huntington's Disease and Related Disorders
    Publication number: 20230235325
    Abstract: Compositions and methods are provided for the inhibition, treatment and/or prevention of Huntington's disease and related disorders.
    Type: Application
    Filed: October 7, 2022
    Publication date: July 27, 2023
    Inventors: Beverly L. Davidson, Alejandro Mas Monteys, Shauna Ebanks
  • Compositions and methods for treating Huntington's disease and related disorders
    Patent number: 11473084
    Abstract: Compositions and methods are provided for the inhibition, treatment and/or prevention of Huntington's disease and related disorders.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: October 18, 2022
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Beverly L. Davidson, Alejandro Mas Monteys, Shauna Ebanks
  • CRISPR INTERFERENCE BASED HTT ALLELIC SUPPRESSION AND TREATMENT OF HUNTINGTON DISEASE
    Publication number: 20210189426
    Abstract: The invention provides expression cassettes and vectors, such as viral (e.g., AAV) vectors, comprising a first nucleic acid encoding a nuclease defective Cas 9 (dCas9) polypeptide and a second nucleic acid encoding a guide polynucleotide that targets the dCas9 polypeptide to the transcriptional start site of an allele encoding a mutant huntingtin gene (HTT)-encoded protein. Also provided are pharmaceutical composition comprising the disclosed expression cassettes and vectors, as well as methods of inhibiting expression of a mutant HTT protein and of treating Huntington's Disease and symptoms associated with the disease.
    Type: Application
    Filed: May 15, 2019
    Publication date: June 24, 2021
    Applicant: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Beverly L. DAVIDSON, Alejandro Mas MONTEYS, Shauna EBANKS
  • Compositions and Methods for Treating Huntington's Disease and Related Disorders
    Publication number: 20190055552
    Abstract: Compositions and methods are provided for the inhibition, treatment and/or prevention of Huntington's disease and related disorders.
    Type: Application
    Filed: October 11, 2016
    Publication date: February 21, 2019
    Inventors: Beverly L. Davidson, Alejandro Mas Monteys, Shauna Ebanks