Abstract: The disclosed techniques include applying one or more voltage pulses to a working electrode of a sensor probe. The techniques may also involve measuring, using a current sensor, a set of one or more current responses corresponding to the applied one or more voltage pulses, wherein the set of one or more current responses form a quasi-Cottrell profile that approximates a portion of a Cottrell curve. The techniques may further involve comparing a characteristic of the quasi-Cottrell profile to sets of predetermined Cottrell profiles. The techniques may further involve calibrating the current sensor based on the comparison.

Abstract: The disclosed techniques include applying, using a voltage controller, multiple voltage pulses to a working electrode of a two-electrode sensor probe, and measuring, using a current sensor, the current response to the applied multiple voltage pulses. The techniques also include analyzing, using a processor, the measured current response, and calibrating, using a processor, the current sensor on the basis of the analyzed measured current response. The techniques further include determining, using a processor, a glucose concentration value on the basis of the calibrated current sensor, and transmitting, using a transmitter, the determined glucose concentration value to a receiver.

Abstract: Techniques are disclosed for measuring an analyte in a biological system. A system may include a medical device with an electrochemical sensor configured to sense the concentration of a plurality of analytes present in a biological system. Processing circuitry of the system may retrieve, identify, and process a respective signal from a respective work electrode to determine the concentration of a respective analyte. The system may further include an implantable medical device configured to sense a cardiac electrogram (EGM). In some examples, the system may be configured to determine one or more patient-specific relationships between the respective signals of the electrochemical sensor and the cardiac EGM during a first period of time. Based on the patient-specific relationships, the system may estimate concentrations of the one or more analytes corresponding to the respective signals based on the cardiac EGM of the patient collected over a second period of time.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: Example techniques, devices, and systems are described herein. An example device includes stimulation generation circuitry, sensing circuitry, and processing circuitry. The processing circuitry is configured to control the stimulation generation circuitry to generate a first stimulation signal having a first stimulation recharge parameter for delivery to target anatomy and receive from the sensing circuitry a sensed evoked response signal. The processing circuitry is configured to analyze the sensed evoked response signal for one or more artifacts and adjust, based on the one or more artifacts, the first stimulation recharge parameter to determine a second stimulation recharge parameter. The processing circuitry is also configured to control the stimulation generation circuitry to generate a second stimulation signal having the second stimulation recharge parameter for delivery to the target anatomy.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: An analyte sensor apparatus for detecting an analyte in a target environment includes a plurality of biotransducers and a controller. The plurality of biotransducers are configured to provide a baseline signal, one or more analyte signals, and at least one error condition signal. The plurality of biotransducers at least one reference biotransducer, one or more working biotransducers, and at least one working as reference biotransducer. The controller is operatively coupled to the plurality of biotransducers and is configured to receive the baseline signal, the one or more analyte signals, and the error correction signal. The controller is further configured to determine and/or output one or more adjusted analyte levels using the baseline signal, the one or more analyte signals, and the error correction signal.

Abstract: A medical device system for delivering a neuromodulation therapy includes a delivery tool for deploying an implantable medical device at a neuromodulation therapy site. The implantable medical device includes a housing, an electronic circuit within the housing, and an electrical lead comprising a lead body extending between a proximal end coupled to the housing and a distal end extending away from the housing and at least one electrode carried by the lead body. The delivery tool includes a first cavity for receiving the housing and a second cavity for receiving the lead. The first cavity and the second cavity are in direct communication for receiving and deploying the housing and the lead coupled to the housing concomitantly as a single unit.

Abstract: A calibration method and related systems for colorimetric chemical assay and a fluid sensor apparatus using the same are provided. Reference measurements are taken from both a digital camera and a spectrometer. The digital camera is installed in the fluid sensor apparatus. Subsequently, color measurements from the digital camera are then converted and compared to prior spectrometric measurements to perform a colorimetric analysis.

Abstract: The disclosed techniques include applying, using a voltage controller, multiple voltage pulses to a working electrode of a two-electrode sensor probe, and measuring, using a current sensor, the current response to the applied multiple voltage pulses. The techniques also include analyzing, using a processor, the measured current response, and calibrating, using a processor, the current sensor on the basis of the analyzed measured current response. The techniques further include determining, using a processor, a glucose concentration value on the basis of the calibrated current sensor, and transmitting, using a transmitter, the determined glucose concentration value to a receiver.

Abstract: Disclosed herein are sensors for sensing analyte concentration values, and methods of operating such sensors. The sensors include a sensor probe comprising two electrodes; a voltage controller operably connected to the two electrodes of the probe, the voltage controller operable to apply multiple voltage pulses to one of the electrodes; a current sensor operable to measure a current response to the multiple voltage pulses; and a processor module operably connected to the current sensor, the processor module operable to calibrate the current sensor on the basis of the current response.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A medical device system for delivering a neuromodulation therapy includes a delivery tool for deploying an implantable medical device at a neuromodulation therapy site. The implantable medical device includes a housing, an electronic circuit within the housing, and an electrical lead comprising a lead body extending between a proximal end coupled to the housing and a distal end extending away from the housing and at least one electrode carried by the lead body. The delivery tool includes a first cavity for receiving the housing and a second cavity for receiving the lead. The first cavity and the second cavity are in direct communication for receiving and deploying the housing and the lead coupled to the housing concomitantly as a single unit.

Abstract: A medical device system for delivering a neuromodulation therapy includes a delivery tool for deploying an implantable medical device at a neuromodulation therapy site. The implantable medical device includes a housing, an electronic circuit within the housing, and an electrical lead comprising a lead body extending between a proximal end coupled to the housing and a distal end extending away from the housing and at least one electrode carried by the lead body. The delivery tool includes a first cavity for receiving the housing and a second cavity for receiving the lead. The first cavity and the second cavity are in direct communication for receiving and deploying the housing and the lead coupled to the housing concomitantly as a single unit.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: Disclosed herein are sensors for sensing analyte concentration values, and methods of operating such sensors. The sensors include a sensor probe comprising two electrodes; a voltage controller operably connected to the two electrodes of the probe, the voltage controller operable to apply multiple voltage pulses to one of the electrodes; a current sensor operable to measure a current response to the multiple voltage pulses; and a processor module operably connected to the current sensor, the processor module operable to calibrate the current sensor on the basis of the current response.

Abstract: A medical device system for delivering a neuromodulation therapy includes a delivery tool for deploying an implantable medical device at a neuromodulation therapy site. The implantable medical device includes a housing, an electronic circuit within the housing, and an electrical lead comprising a lead body extending between a proximal end coupled to the housing and a distal end extending away from the housing and at least one electrode carried by the lead body. The delivery tool includes a first cavity for receiving the housing and a second cavity for receiving the lead. The first cavity and the second cavity are in direct communication for receiving and deploying the housing and the lead coupled to the housing concomitantly as a single unit.