Abstract: The present invention generally relates, in certain aspects, to relatively small devices applied to the skin, modular systems, and methods of use thereof. In some aspects, the device is constructed and arranged to have more than one module. For instance, the device may have a module for delivering to and/or withdrawing fluid from the skin and/or beneath the skin of a subject and a module for transmitting a signal indicative of the fluid delivered to and/or withdrawn from the skin and/or beneath the skin of the subject, a module for analyzing a fluid withdrawn from the skin and/or beneath the skin of the subject, or the like. In some embodiments, the modules are connectable and/or detachable from each other, and in some cases, the connections and/or detachments may be performed while the device is in contact with the subject, e.g., while affixed to the subject.

Abstract: Pharmaceutical drugs and formulations suitable for iontophoresis thereof that provide enhanced iontophoretic delivery of an anti-fungal drug to at least one body surface, such as a nail, are described. Also described are pharmaceutical formulations suitable for iontophoresis comprising terbinafine and methods for administering terbinafine to a body surface via iontophoresis. When the drug source is introduced into the nail using a mask, terbinafine concentrations in peripheral areas of nail following iontophoretic treatment are less than drug concentrations directly under the mask. Further, differences in delivered drug concentrations is effectuated by creating drug delivery gradients. Drug can be delivered to dissimilar tissues based on different transfer efficiencies exhibited by the dissimilar tissues, resulting in higher percentage delivery in one tissue vs. another tissue.

Abstract: The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

Abstract: The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the to extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

Abstract: A load control system and apparatus to control the load to different elements is disclosed. The load control system is attached to both an air conditioner and a pool filter system. The pool filter system has a predetermined run time and is only operating when the air conditioner is not. When the air conditioner turns on, the load to the pool filter system is disconnected. When the air conditioner turns off, the load is returned to the pool filter which resumes running at the point in the run time where the pool filter had previously left off. The load control system provides a more efficient and better use of energy resources.

Abstract: A spa comprises a water enclosure for holding a quantity of water. The water enclosure has two or more zones. Each of the zones has a plurality of jets. There is a control pad for each of the zones configured to control the water temperature and water pressure coming out of the plurality of jets in each zone.

Abstract: An irrigation system comprises an irrigation zone, a controller, a valve, one or more pipes and at least one ground sensor. The system of pipes is connected to the value, which is operable to read water quantity per unit time. The ground sensors determine water flow and absorption by observing changes in surface temperature. The controller is in communication with the ground sensors and regulates water flow to the irrigation zone based on the readings from the ground sensors. The controller is programmed to deliver a predetermined volume of water and the ground sensor uses an infrared thermometer.

Abstract: Peelable seals including porous inserts are described. An example peelable seal includes a porous insert positioned between a first sheet and a second sheet. The porous insert includes a plurality of interwoven strands and a plurality of pores adjacent the interwoven strands through which a bond is formed between the first sheet and the second sheet when heat is applied to at least one of the first sheet, the second sheet or the porous insert.

Abstract: An apparatus and methods for delivering ocular implants or microimplants. The apparatus is ergonomically designed for ease of use, and a simple manual depression of an actuator produces proportional movement of a linkage causing the implant or microimplant to be ejected through a cannula disposed at the desired location in the eye. Small gauge cannulas are provided for self-sealing methods of delivery.

Abstract: A load control system and apparatus to control the load to different elements is disclosed. The load control system is attached to both an air conditioner and a pool filter system. The pool filter system has a predetermined run time and is only operating when the air conditioner is not. When the air conditioner turns on, the load to the pool filter system is disconnected. When the air conditioner turns off, the load is returned to the pool filter which resumes running at the point in the run time where the pool filter had previously left off. The load control system provides a more efficient and better use of energy resources.

Abstract: An under floor heating element incorporating a scrim having one or more pairs of heating and/or sensor wires arranged in a continuous pattern such that pair members are disposed in crossing relation to one another. The pair members may be cut and joined to establish electrical connections at defined crossing points to establish feedback loop circuits with a control element.

Abstract: A channeled under floor heating element incorporating channeled areas for accepting heat and sensor wires. The inventive channeled under floor heating element includes an arrangement of seam structures defining channels housing substantially discrete elongate heating and sensing elements arranged in a substantially similar pattern.

Abstract: A warming mattress and mattress pad incorporating an insert layer or sheet with a scrim having one or more pairs of heating and/or sensor wires arranged in a continuous pattern such that pair members are disposed in crossing relation to one another. The pair members may be cut and joined to establish electrical connections at defined crossing points to establish feedback loop circuits with a control element.

Abstract: A warming mattress and mattress pad incorporating channeled areas for accepting heat and sensor wires. The inventive mattress and mattress pad includes an arrangement of seam structures defining channels housing substantially discrete elongate heating and sensing elements arranged in a substantially similar pattern within the mattress or mattress pad interior.

Abstract: An under floor heating element incorporating a scrim having one or more pairs of heating and/or sensor wires arranged in a continuous pattern such that pair members are disposed in crossing relation to one another. The pair members may be cut and joined to establish electrical connections at defined crossing points to establish feedback loop circuits with a control element.

Abstract: A warming mattress and mattress pad incorporating an insert layer or sheet with a scrim having one or more pairs of heating and/or sensor wires arranged in a continuous pattern such that pair members are disposed in crossing relation to one another. The pair members may be cut and joined to establish electrical connections at defined crossing points to establish feedback loop circuits with a control element.

Abstract: A warming blanket incorporating channeled areas for accepting heat and/or sensor wires. The inventive blanket includes multiple layers of knitted, woven or non-woven fabrics that are welded together with ultrasonic seams to define channels through which wires for resistive heating can be placed. This composite may be produced in a continuous process, providing the composite in roll form.

Abstract: A warming mattress and mattress pad incorporating channeled areas for accepting heat and sensor wires. The inventive mattress and mattress pad includes an arrangement of seam structures defining channels housing substantially discrete elongate heating and sensing elements arranged in a substantially similar pattern within the mattress or mattress pad interior.

Abstract: A channeled under floor heating element incorporating channeled areas for accepting heat and sensor wires. The inventive channeled under floor heating element includes an arrangement of seam structures defining channels housing substantially discrete elongate heating and sensing elements arranged in a substantially similar pattern.

Abstract: A warming blanket incorporating channeled areas for accepting heat and sensor wires. The inventive blanket includes an arrangement of seam structures defining channels housing substantially discrete elongate heating and sensing elements arranged in a substantially similar pattern within the blanket interior.