Abstract: A dental hygiene wipe for cleaning exterior surfaces and interproximal areas of teeth. The inventive device includes a flexible base substrate having an abrasive cleaning pad coupled to the base substrate. The abrasive cleaning pad includes a plurality of quarter-spherical projections which can be used to effect cleaning and polishing of tooth enamel. The abrasive cleaning pad is preferably comprised of a porous material which can be impregnated with a dentifrice, mouth wash, or other moist substance.