Patents by Inventor Shawn M. Bauer

Shawn M. Bauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11414410
    Abstract: The present invention is directed to methods of treating multiple myeloma by administering a compound of Formula (I) or pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: August 16, 2022
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Shawn M. Bauer, Zhaozhong J. Jia, Mukund Mehrotra, Yonghong Song, Qing Xu, Wolin Huang, Chandrasekar Venkataramani, Jack W. Rose, Anjali Pandey
  • Publication number: 20200239458
    Abstract: The present invention is directed to compounds of formula I-II and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: November 26, 2019
    Publication date: July 30, 2020
    Inventors: SHAWN M. BAUER, ZHAOZHONG J. JIA, MUKUND MEHROTRA, YONGHONG SONG, QING XU, WOLIN HUANG, CHANDRASEKAR VENKATARAMANI, JACK W. ROSE, ANJALI PANDEY
  • Patent number: 10533001
    Abstract: The present invention is directed to topical pharmaceutical compositions of Formula (If) or pharmaceutically acceptable salt thereof, which act as inhibitors of syk and/or JAK kinase activity. The described topical pharmaceutical compositions are useful in preventing or treating a number of conditions mediated at least in part by syk and/or JAK kinase activity.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: January 14, 2020
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Shawn M. Bauer, Zhaozhong J. Jia, Mukund Mehrotra, Yonghong Song, Qing Xu, Wolin Huang, Chandrasekar Venkataramani, Jack W. Rose, Anjali Pandey
  • Publication number: 20180186783
    Abstract: The present invention is directed to compounds of formula I-II and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: November 30, 2017
    Publication date: July 5, 2018
    Inventors: Shawn M. Bauer, ZHAOZHONG J. JIA, MUKUND MEHROTRA, YONGHONG SONG, QING XU, WOLIN HUANG, CHANDRASEKAR VENKATARAMANI, JACK W. ROSE, ANJALI PANDEY
  • Patent number: 9902688
    Abstract: The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: February 27, 2018
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Zhaozhong J. Jia, Yonghong Song, Qing Xu, Brian Kane, Shawn M. Bauer, Anjali Pandey
  • Patent number: 9868729
    Abstract: Provided are methods of treating inflammatory disorders, autoimmune disorders, or a hematological malignancies using compounds of formula I and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof. Such disorders and conditions include leukemia and Non Hodgkin's Lymphoma.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: January 16, 2018
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Shawn M. Bauer, Anjali Pandey
  • Patent number: 9676756
    Abstract: Provided are substituted pyrimidinyl compounds for inhibition of JAK and/or Syk kinase, pharmaceutical compositions thereof, methods for inhibiting JAK and/or Syk kinase activity, and methods for treating conditions mediated at least in part by JAK and/or Syk kinase activity.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: June 13, 2017
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Shawn M. Bauer, Zhaozhong J. Jia, Yonghong Song, Anjali Pandey
  • Patent number: 9579320
    Abstract: The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: February 28, 2017
    Assignee: Portola Pharmaceuticals, Inc.
    Inventors: Zhaozhong J. Jia, Chandrasekar Venkataramani, Wolin Huang, Mukund Mehrotra, Yonghong Song, Qing Xu, Shawn M. Bauer, Jack W. Rose, Brian Kane, Anjali Pandey
  • Publication number: 20160318852
    Abstract: The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.
    Type: Application
    Filed: May 10, 2016
    Publication date: November 3, 2016
    Inventors: Zhaozhong J. Jia, Yonghong Song, Qing Xu, Brian Kane, Shawn M. Bauer, Anjali Pandey
  • Patent number: 9359375
    Abstract: The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: June 7, 2016
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Zhaozhong J. Jia, Yonghong Song, Qing Xu, Brian Kane, Shawn M. Bauer, Anjali Pandey
  • Patent number: 9359308
    Abstract: Provided are pyrazine compounds of Formula (I) for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibition Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.
    Type: Grant
    Filed: November 23, 2012
    Date of Patent: June 7, 2016
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Yonghong Song, Qing Xu, Zhaozhong J. Jia, Brian Kane, Shawn M. Bauer, Anjali Pandey
  • Publication number: 20150353495
    Abstract: The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: June 29, 2015
    Publication date: December 10, 2015
    Inventors: Shawn M. BAUER, YONGHONG SONG, QING XU, JACK W. ROSE, ZHAOZHONG J. JIA, BRIAN KANE, WOLIN HUANG, ANJALI PANDEY, MUKUND MEHROTRA
  • Publication number: 20150297595
    Abstract: The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 22, 2015
    Inventors: Zhaozhong J. Jia, Chandrasekar Venkataramani, Wolin Huang, Mukund Mehrotra, Yonghong Song, Qing Xu, Shawn M. Bauer, Jack W. Rose, Brian Kane, Anjali Pandey
  • Patent number: D772308
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: November 22, 2016
    Assignee: Clark Equipment Company
    Inventors: Jeremy A. Harms, James M. Breuer, Michael D. Wetzel, Shawn M. Bauer, Jinhup Yeu
  • Patent number: D772954
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: November 29, 2016
    Assignee: Clark Equipment Company
    Inventors: Jeremy A. Harms, James M. Breuer, Michael D. Wetzel, Shawn M. Bauer, Jinhup Yeu
  • Patent number: D772955
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: November 29, 2016
    Assignee: Clark Equipment Company
    Inventors: Jeremy A. Harms, James M. Breuer, Michael D. Wetzel, Shawn M. Bauer, Jinhup Yeu
  • Patent number: D772956
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: November 29, 2016
    Assignee: Clark Equipment Company
    Inventors: Jeremy A. Harms, James M. Breuer, Michael D. Wetzel, Shawn M. Bauer, Jinhup Yeu
  • Patent number: D776724
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: January 17, 2017
    Assignee: Clark Equipment Company
    Inventors: Jeremy A. Harms, James M. Breuer, Michael D. Wetzel, Shawn M Bauer, Jinhup Yeu
  • Patent number: D776725
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: January 17, 2017
    Assignee: Clark Equipment Company
    Inventors: Jeremy A. Harms, James M. Breuer, Michael D. Wetzel, Shawn M. Bauer, Jinhup Yeu
  • Patent number: D777218
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: January 24, 2017
    Assignee: Clark Equipment Company
    Inventors: Jeremy A. Harms, James M. Breuer, Michael D. Wetzel, Shawn M. Bauer, Jinhup Yeu