Patents by Inventor Shawn Scranton

Shawn Scranton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE
    Publication number: 20070135431
    Abstract: Disclosed herein are carbonyl compounds of having the structural formula: or a salt, ester, or prodrug thereof, Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.
    Type: Application
    Filed: December 8, 2006
    Publication date: June 14, 2007
    Applicant: KALYPSYS, INC
    Inventors: Nicholas Smith, Celine Bonnefous, Joseph Payne, Timothy Hoffman, Paul Wash, Christian Hassig, Shawn Scranton
  • INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE
    Publication number: 20070135438
    Abstract: Disclosed herein are carbonyl compounds of having the structural formula: or a pharmaceutically acceptable salt, ester, or prodrug thereof, Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.
    Type: Application
    Filed: December 8, 2006
    Publication date: June 14, 2007
    Applicant: KALYPSYS, INC.
    Inventors: Joseph Payne, Nicholas Smith, Shawn Scranton, Christian Hassig
  • Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease
    Publication number: 20070027184
    Abstract: Disclosed herein are sulfonamide compounds of Formula VII as described herein. Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.
    Type: Application
    Filed: July 27, 2006
    Publication date: February 1, 2007
    Inventors: James Malecha, Stewart Noble, Brandon Wiley, Timothy Hoffman, Celine Bonnefous, Michael Sertic, Paul Wash, Nicholas Smith, Christian Hassig, Shawn Scranton, Joseph Payne, Jeffery Hager
  • Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders
    Publication number: 20060252807
    Abstract: The present invention relates to compounds and methods useful as inhibitors of p38 kinase for the treatment or prevention and treatment of diseases such as inflammatory diseases, autoimmune diseases, destructive bone disorders, proliferative disorders, angiogenic disorders, infectious diseases, neurodegenerative diseases, and viral diseases.
    Type: Application
    Filed: April 20, 2006
    Publication date: November 9, 2006
    Inventors: Daniel Severance, Elisabeth Gardiner, Stewart Noble, Boliang Lou, Allen Borchardt, Jeffrey Roppe, Mehmet Kahraman, Dana Siegel, Shawn Scranton