Patents by Inventor Shawn Winer

Shawn Winer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LYMPHOCYTE CONTROL OF OBESITY AND INSULIN RESISTANCE
    Publication number: 20110091447
    Abstract: Methods for the treatment, inhibition, prevention, etc. of metabolic syndrome (MetSyn) and/or Type-2 diabetes (T2D) using a T cell activating antibody that stimulates activation and immunomodulation of T-cells to affect the immune environment of adipose tissue and improve insulin sensitivity. Also methods for the treatment, inhibition, prevention, amelioration, reversal, etc., of metabolic syndrome (MetSyn) and/or Type-2 diabetes (T2D) using leukemia inhibitory factor (LIF), or a functional portion thereof. Compositions administered to individuals having or at risk of developing MetSyn and/or T2D may include pharmaceutical compositions. Methods may also provide tolerogenic vaccines based on the administration of identified auto-antigens from individuals having or at risk of developing MetSyn and/or T2D.
    Type: Application
    Filed: March 13, 2009
    Publication date: April 21, 2011
    Applicant: THE HOSPITAL FOR SICK CHILDREN
    Inventors: Hans-Michael Dosch, Yin Chan, Shawn Winer, Geoffrey Palster
  • Prevention of primary sjogren' s Syndrome by ICA69 deficiency
    Publication number: 20080058271
    Abstract: This invention relates to identification of an autoantigen implicated in the development and progression of Sjögren's Syndrome (pSS); particularly to the disease modifying effect of creating a deficiency in the ICA69 autoantigen; and most particularly to development of diagnostic and therapeutic avenues, means for the differential diagnosis of pSS versus other autoimmune disease, e.g. Systemic lupus erythematosis (SLE), and procedures for immunotherapeutic treatment effective to alter the course and progression of pSS.
    Type: Application
    Filed: August 28, 2007
    Publication date: March 6, 2008
    Inventors: Hans-Michael Dosch, Shawn Winer
  • Prevention of primary Sjogren's Syndrome by ICA69 deficiency
    Publication number: 20060074022
    Abstract: This invention relates to identification of an autoantigen implicated in the development and progression of Sjögren's Syndrome (pSS); particularly to the disease modifying effect of creating a deficiency in the ICA69 autoantigen; and most particularly to development of diagnostic and therapeutic avenues, means for the differential diagnosis of pSS versus other autoimmune disease, e.g. Systemic lupus erythematosis (SLE), and procedures for immunotherapeutic treatment effective to alter the course and progression of pSS.
    Type: Application
    Filed: September 30, 2005
    Publication date: April 6, 2006
    Applicant: The Hospital for Sick Children Research Institute
    Inventors: Hans-Michael Dosch, Shawn Winer
  • Prevention of primary Sjogren's Syndrome by ICA69 deficiency
    Publication number: 20040123335
    Abstract: This invention relates to identification of an autoantigen implicated in the development and progression of Sjögren's Syndrome (pSS); particularly to the disease modifying effect of creating a deficiency in the ICA69 autoantigen; and most particularly to development of diagnostic and therapeutic avenues, means for the differential diagnosis of pSS versus other autoimmune disease, e.g. Systemic lupus erythematosis (SLE), and procedures for immunotherapeutic treatment effective to alter the course and progression of pSS.
    Type: Application
    Filed: October 3, 2003
    Publication date: June 24, 2004
    Inventors: Hans-Michael Dosch, Shawn Winer