Abstract: A method for readying a fluid sensor associated with a medical device includes attaching a flow restrictor to a fluid outlet of the fluid sensor. The fluid sensor includes a fluid channel, a fluid inlet at a first end of the fluid channel configured to couple to an outlet of an administrable fluid source, and the fluid outlet at a second end of the fluid channel. Fluid is delivered from the administrable fluid source to the fluid channel through the fluid inlet. A syringe actuation device including a force limiting device may be used to deliver the fluid. The fluid is pressurized in the fluid channel between the fluid inlet and the flow restrictor to wet an interior surface of the fluid channel with the fluid. The flow restrictor is removed from the fluid outlet.

Abstract: The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula (I) or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, R2 and R3 are as defined in the description. HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

Abstract: A method for readying a fluid sensor associated with a medical device includes attaching a flow restrictor to a fluid outlet of the fluid sensor. The fluid sensor includes a fluid channel, a fluid inlet at a first end of the fluid channel configured to couple to an outlet of an administrable fluid source, and the fluid outlet at a second end of the fluid channel. Fluid is delivered from the administrable fluid source to the fluid channel through the fluid inlet. A syringe actuation device including a force limiting device may be used to deliver the fluid. The fluid is pressurized in the fluid channel between the fluid inlet and the flow restrictor to wet an interior surface of the fluid channel with the fluid. The flow restrictor is removed from the fluid outlet.

Abstract: A liquid agrochemical composition includes an agrochemical including a fungicide and/or an herbicide chosen from dicamba, 2,4-D, glufosinate, and combinations thereof and in an amount of from about 0.05 to about 60 weight percent based on a total weight of the composition; and a surfactant in an amount of from about 0.05 to about 50 weight percent based on a total weight of the composition and consisting of; (i) at least one alkoxylated monoglyceride in an amount of from about 30 to about 45 weight percent, (ii) at least one alkoxylated diglyceride in an amount of from about 40 to about 50 weight percent, (iii) at least one alkoxylated triglyceride in an amount of from about 8 to about 10 weight percent, and (iv) at least one alkoxylated glycerin in an amount of from about 6 to about 8 weight percent, each based on a total weight of the surfactant.

Abstract: An agrochemical composition includes: a linear fatty acid having a C8 to C10 alkyl chain; and an additive chosen from a diluent, an alkoxylated phosphate ester surfactant, and combinations thereof, wherein the alkoxylated phosphate ester surfactant has a degree of alkoxylation of from about 10 to about 100 and is chosen from alkoxylated C12-C22 alkyl phosphate esters, alkoxylated phosphate esters formed from an alkoxylated triglyceride having at least one pendant hydroxyl group, an alkoxylated phosphate ester formed from an alkoxylated alkylamine, and combinations thereof; and wherein the diluent is chosen from C4-C10 linear or branched alcohols and their propoxylates, branched C5-C10 monocarboxylic acids, methyl and ethyl esters of linear or branched C8-C10 fatty acids, tall oil fatty acid, trialkyl C2-C8 linear or branched phosphates, aromatic solvents, mineral oils, methyl benzoate, methyl salicylate, octyl acetates, octyl lactate, alkylnitriles, and combinations thereof.

Abstract: An herbicidal composition comprising (a) glyphosate or a derivative thereof, (b) an amidoalkylamine surfactants having the general structure: wherein R1 is a hydrocarbyl having from about 1 carbon atoms to about 22 carbon atoms, and R2, R3, and R4 are each independently hydrocarbyl having from about 1 carbon atom to about 6 carbon atoms; and (c) at least one co-surfactant.

Abstract: Disclosed are thickened organic liquid compositions comprising an organic liquid and a polymeric rheology modifier wherein the polymeric rheology modifier is obtainable by co-polymerizing at least two of a bicyclic (meth)acrylate ester, an alkyl (meth)acrylate, and an aromatic vinyl monomer. Also disclosed are thickened organic liquid dispersions with suspended solids and methods of stabilizing dispersions using polymeric rheology modifiers.

Abstract: An agrochemical composition includes an agrochemical and a surfactant that has a structure (I)-(III). The surfactant may be further defined as an alkyl etheramine polyglycerol surfactant. In another embodiment, the surfactant may be further defined as an amine oxide, as also described above. In another embodiment, the surfactant may be further defined as a quat or quaternary ammonium compound.

Abstract: A surfactant has a structure (I)-(VI) and may be used in an agrochemical composition that includes at least one surfactant of this disclosure and an agrochemical. The surfactant may be further defined as alkyl amine polyglycerol or alkyl polyamine polyglycerol, or alkyl polyglycerylamine. In another embodiment, the surfactant may be further defined as an amine oxide, as also described above. In another embodiment, the surfactant may be further defined as a quat or quaternary ammonium compound.

Abstract: An agrochemical composition includes an agrochemical and a surfactant that has a structure (I)-(VI). The surfactant may be described as an alkyl amidoamine glycerol surfactant, an oxide thereof, or as a quaternary ammonium compound thereof.

Abstract: An epoxidized oil-based surfactant is the reaction product of an epoxidized compound and a primary and/or secondary alkanolamine, wherein the epoxidized compound is chosen from an epoxidized oil, an epoxidized fatty acid, an epoxidized fatty acid ester, and combinations thereof. An herbicidal composition includes glyphosate or a salt thereof and at least one epoxidized oil-based surfactant. The herbicidal composition is used in a method of controlling unwanted vegetation wherein the method includes the step of applying to the unwanted vegetation a herbicidally effective amount of the aforementioned herbicidal composition. The epoxidized oil-based surfactant is prepared using a method that includes reacting the epoxidized compound and the primary and/or secondary alkanolamine.

Abstract: An herbicidal composition comprising (a) glyphosate or a derivative thereof, (b) an amidoalkylamine surfactant of formula (1): wherein R1 is a hydrocarbyl having from about 1 carbon atoms to about 22 carbon atoms, R2 and R3 are each independently hydrocarbyl or substituted hydrocarbyl having from 1 to about 6 carbon atoms and R4 is hydrocarbylene or substituted hydrocarbylene having from 1 to about 6 carbon atoms and (c) a co-surfactant component comprising at least one co-surfactant selected from, for example, alkoxylated tertiary amine oxides, amidoamine alkoxylates, and betaines.

Abstract: An herbicidal composition comprising (a) glyphosate or a derivative thereof, (b) an amidoalkylamine surfactant of formula (1): wherein R1 is a hydrocarbyl having from about 1 carbon atoms to about 22 carbon atoms, R2 and R3 are each independently hydrocarbyl or substituted hydrocarbyl having from 1 to about 6 carbon atoms and R4 is hydrocarbylene or substituted hydrocarbylene having from 1 to about 6 carbon atoms and (c) a co-surfactant component comprising at least one co-surfactant selected from, for example, alkoxylated tertiary amine oxides, amidoamine alkoxylates, and betaines.

Abstract: Disclosed are thickened organic liquid compositions comprising an organic liquid and a polymeric rheology modifier wherein the polymeric rheology modifier is obtainable by co-polymerizing at least two of a bicyclic (meth)acrylate ester, an alkyl (meth)acrylate, and an aromatic vinyl monomer. Also disclosed are thickened organic liquid dispersions with suspended solids and methods of stabilizing dispersions using polymeric rheology modifiers.

Abstract: This disclosure provides an agricultural composition comprising at least one agrochemical and at least one alkylamine glycidol surfactant of the structure I: where R is C4-C22 linear or branched, saturated or non-saturated hydrocarbon group with or without pendant hydroxyl groups; x is about 0 to about 30, preferably about 1 to about 20, more preferably about 1 to about 10, more preferably about 1 to about 5; y is about 0 to about 30, preferably about 1 to about 20, more preferably about 1 to about 10, more preferably about 1 to about 5; x+y?about 2 and up to about 30, and Gly is a glyceryl residue.

Abstract: A personal care formulation comprises a dermatologically acceptable organic liquid and a cross linked (meth)acrylate copolymer, wherein the organic liquid is thickened by the cross linked (meth)acrylate copolymer, and wherein the cross linked (meth)acrylate copolymer comprises at least one alkyl (meth)acrylate and at least one of the following monomers: a bicyclic (meth)acrylate different from the alkyl (meth)acrylate, and an aromatic vinyl monomer. In one embodiment the formulation can further comprise water and be in the form of a water-in-oil emulsion. In another embodiment the formulation can comprise water and an aqueous thickener and be in the form of an oil-in-water emulsion. The personal care formulation can be a hair care formulation, a skin care formulation, or a sunscreen formulation.

Abstract: An herbicidal composition comprising (a) glyphosate or a derivative thereof, (b) an amidoalkylamine surfactants having the general structure: wherein R1 is a hydrocarbyl having from about 1 carbon atoms to about 22 carbon atoms, and R2, R3, and R4 are each independently hydrocarbyl having from about 1 carbon atom to about 6 carbon atoms; and (c) at least one co-surfactant.

Abstract: An agricultural formulation comprises: at least one agricultural active; and an alkyl imino dipropionate having the formula: wherein R is a C6-C24, linear or branched, alkyl group, and wherein each M is independently a cation chosen from Mg2+, Ca2+, NH4+, K+, and Na+, and wherein the formulation is free of an alkylamine and/or derivative thereof if R is lauryl.