Abstract: The present disclosure provides CpG oligodeoxynucleotides (ODNs) as immunogenic molecules, and their use in methods of initiating or promoting innate or adaptive immunity in fish or increasing an immune response against an antigen in fish.

Abstract: A system is provided for tracking, in a distributed water infrastructure, water usage by category. The system may comprise at least one processor configured to receive from at least one sensor associated with the distributed water infrastructure signals indicative of water usage in the distributed water infrastructure. The system may, based on the signals indicative of water usage, construct a plurality of profiles. The system may assign each profile to one of a plurality of water usage categories. The system may collect, from the at least one sensor, signals indicative of water usage for substantially all water delivered through the distributed water infrastructure in a time period. The system may construct a plurality of water usage profiles in the aggregate, encompassing substantially all water delivered through the distributed water infrastructure in the time period. The system may assign each constructed water usage profile to one of the plurality of water usage categories.

Abstract: An abnormal consumption detection system is provided with remote valve control for a distributed water infrastructure. The system may comprise an electronically controllable valve, a remote communication transmitter, a remote communication receiver, at least one sensor for measuring water flow information associated with the distributed water infrastructure, and at least one processor. The system may determine from the water flow information obtained from the at least one sensor a potential abnormal consumption associated with the distributed water infrastructure. The system may automatically close a valve, without human intervention, when the potential abnormal consumption is determined. The system may transmit, via the remote communication transmitter to a remote administrator, alert information about the potential abnormal consumption to enable an administrator to decide based on the transmitted information whether to reopen the valve.

Abstract: A system is provided for tracking, in a distributed water infrastructure, water usage by category. The system may comprise at least one processor configured to receive from at least one sensor associated with the distributed water infrastructure signals indicative of water usage in the distributed water infrastructure. The system may, based on the signals indicative of water usage, construct a plurality of profiles. The system may assign each profile to one of a plurality of water usage categories. The system may collect, from the at least one sensor, signals indicative of water usage for substantially all water delivered through the distributed water infrastructure in a time period. The system may construct a plurality of water usage profiles in the aggregate, encompassing substantially all water delivered through the distributed water infrastructure in the time period. The system may assign each constructed water usage profile to one of the plurality of water usage categories.

Abstract: A system is provided for determining whether a specific water appliance is malfunctioning. The system may comprise at least one processor configured to detect, from at least one sensor in a distributed water infrastructure upstream of the plurality of water appliances, a plurality of normal water usage profiles; associate at least one of the plurality of profiles with each of the plurality of appliances; detect at least one current water usage profile; and compare the at least one current profile with at least one of the stored profiles to determine a corresponding identity of an associated appliance and to determine if a deviation exists between the stored profile for the identified appliance and the at least one current profile. The deviation may be reflective of a potential malfunction in the associated appliance. The system may initiate remedial action if the deviation, reflective of a potential malfunction, is determined.

Abstract: A system is provided for tracking, in a distributed water infrastructure, water usage by category. The system may comprise at least one processor configured to receive from at least one sensor associated with the distributed water infrastructure signals indicative of water usage in the distributed water infrastructure. The system may, based on the signals indicative of water usage, construct a plurality of profiles. The system may assign each profile to one of a plurality of water usage categories. The system may collect, from the at least one sensor, signals indicative of water usage for substantially all water delivered through the distributed water infrastructure in a time period. The system may construct a plurality of water usage profiles in the aggregate, encompassing substantially all water delivered through the distributed water infrastructure in the time period. The system may assign each constructed water usage profile to one of the plurality of water usage categories.

Abstract: A system is provided for tracking usage of a plurality of water appliances in a distributed water infrastructure. The system may comprise at least one processor configured to receive, from a location in the distributed water infrastructure upstream of the plurality of water appliances, historical water usage measurements; determine from the historical water usage measurements at least one unique water usage signature associated with each of the plurality of water appliances; receive, from the location in the distributed water infrastructure upstream of the plurality of water appliances, current water usage measurements; determine from the current water usage measurements at least one current water usage signature; compare the current water usage signature with at least one of the unique water usage signatures stored in memory to determine a match; and, based on the signature match, ascertain an identifier of a water appliance in current use.

Abstract: A system is provided for detecting abnormal consumption in one portion of a distributed water infrastructure while normal water usage occurs in another portion of the distributed water infrastructure. The system may comprise at least one processor. The system may receive from at least one sensor associated with the distributed water infrastructure indications of regular water usage. The system may determine, from a plurality of indications received over a time period, a plurality of baseline water usage profiles. The system may receive from the at least one sensor a current water usage profile. The system may compare the current water usage profile with the plurality of baseline water usage profiles. The system may determine an abnormal water consumption based on the comparison between the current water usage profile and the plurality of baseline water usage profiles. The system may generate an abnormal water consumption signal when abnormal water consumption is determined.

Abstract: A system is provided for differentiating between overlapping water events in a distributed water infrastructure including a plurality of water appliances. The system may comprise at least one processor. The system may repeatedly measure at least one overall water usage indicator of the distributed water infrastructure, the at least one water usage indicator including at least one of an overall flow rate and an overall flow volume in the distributed water infrastructure. The system may detect, in the repeated measurements, a first sustained increase. The system may store in memory a first indicator of the first sustained increase. The system may attribute in memory the first sustained increase to a first water event in the distributed water infrastructure. The system may, during the first sustained increase, detect in the overall measurements a second sustained increase. The system may store in memory a second indicator of the second sustained increase.

Abstract: A fluid governing system including a fluid inlet and fluid inlet port coupleable to an upstream pipe segment; a fluid outlet and a fluid outlet port coupleable to a downstream pipe segment; a flow unit; a metering inlet path in flow communication with the fluid inlet; a metering outlet path in flow communication with the fluid outlet, the metering inlet path is in flow communication with the metering outlet path through the flow unit which is articulable between the metering inlet path and the metering outlet path; a pressure responsive sealing diaphragm for selective sealing a metering inlet port; an inlet chamber disposed at a face of the sealing diaphragm, the inlet chamber in flow communication with the fluid inlet; a control chamber disposed at an opposite face of the sealing diaphragm; and a control fluid duct extending between the inlet chamber and the control chamber.

Abstract: A fluid flow system comprising a supply line, a fluid control unit and at least one end user; wherein fluid flow through the system is facilitated only upon a certified verification signal generated by the end-user and certifying said verification signal by the fluid control unit.

Abstract: An abnormal consumption detection system is provided with remote valve control for a distributed water infrastructure. The system may comprise an electronically controllable valve, a remote communication transmitter, a remote communication receiver, at least one sensor for measuring water flow information associated with the distributed water infrastructure, and at least one processor. The system may determine from the water flow information obtained from the at least one sensor a potential abnormal consumption associated with the distributed water infrastructure. The system may automatically close a valve, without human intervention, when the potential abnormal consumption is determined. The system may transmit, via the remote communication transmitter to a remote administrator, alert information about the potential abnormal consumption to enable an administrator to decide based on the transmitted information whether to reopen the valve.

Abstract: A system is provided for determining from a location upstream of a plurality of water appliances, whether a specific water appliance is malfunctioning. The system may comprise at least one processor. The system may detect, from at least one sensor in a distributed water infrastructure upstream of the plurality of water appliances, a plurality of normal water usage profiles. The system may associate at least one of the plurality of normal water usage profiles with each of the plurality of water appliances. The system may store each of the plurality of normal water usage profiles in a manner associating each of the plurality of normal water usage profiles with an associated water appliance. The system may detect at least one current water usage profile.

Abstract: A system is provided for tracking usage of a plurality of water appliances in a distributed water infrastructure. The system may comprise at least one processor. The system may receive, from a location in the distributed water infrastructure upstream of the plurality of water appliances, historical water usage measurements. The system may determine from the historical water usage measurements at least one unique water usage signature associated with each of the plurality of water appliances. The system may store in memory each at least one unique water usage signature for each of the plurality of appliances. The system may receive, from the location in the distributed water infrastructure upstream of the plurality of water appliances, current water usage measurements. The system may determine from the current water usage measurements at least one current water usage signature.

Abstract: A system is provided for detecting abnormal consumption in a distributed water infrastructure. The system may receive from at least one sensor associated with the distributed water infrastructure signals indicative of water usage in the distributed water infrastructure, and aggregate groups of signals to construct a plurality of time-based water event profiles, each water event profile containing a distribution of water usage indicators over time. The system may store a subset of the plurality of water event profiles in memory as normal water event profiles, and receive, from the at least one sensor, signals indicative of current water usage in the distributed water infrastructure. The system may construct, from the signals indicative of current water usage, at least one current water event profile, and compare the at least one current water event profile with normal water event profiles stored in the memory.

Abstract: A system is provided for differentiating between overlapping water events in a distributed water infrastructure including a plurality of water appliances. The system may comprise at least one processor. The system may repeatedly measure at least one overall water usage indicator of the distributed water infrastructure, the at least one water usage indicator including at least one of an overall flow rate and an overall flow volume in the distributed water infrastructure. The system may detect, in the repeated measurements, a first sustained increase. The system may store in memory a first indicator of the first sustained increase. The system may attribute in memory the first sustained increase to a first water event in the distributed water infrastructure. The system may, during the first sustained increase, detect in the overall measurements a second sustained increase. The system may store in memory a second indicator of the second sustained increase.

Abstract: A system is provided for detecting abnormal consumption in one portion of a distributed water infrastructure while normal water usage occurs in another portion of the distributed water infrastructure. The system may comprise at least one processor. The system may receive from at least one sensor associated with the distributed water infrastructure indications of regular water usage. The system may determine, from a plurality of indications received over a time period, a plurality of baseline water usage profiles. The system may receive from the at least one sensor a current water usage profile. The system may compare the current water usage profile with the plurality of baseline water usage profiles. The system may determine an abnormal water consumption based on the comparison between the current water usage profile and the plurality of baseline water usage profiles. The system may generate an abnormal water consumption signal when abnormal water consumption is determined.

Abstract: A system is provided for tracking, in a distributed water infrastructure, water usage by category. The system may comprise at least one processor configured to receive from at least one sensor associated with the distributed water infrastructure signals indicative of water usage in the distributed water infrastructure. The system may, based on the signals indicative of water usage, construct a plurality of profiles. The system may assign each profile to one of a plurality of water usage categories. The system may collect, from the at least one sensor, signals indicative of water usage for substantially all water delivered through the distributed water infrastructure in a time period. The system may construct a plurality of water usage profiles in the aggregate, encompassing substantially all water delivered through the distributed water infrastructure in the time period. The system may assign each constructed water usage profile to one of the plurality of water usage categories.

Abstract: A system is provided for determining operational states of specific categories of water appliances using a plurality of geographically distributed water sensors. The system may comprise at least one central processor. The system may receive water appliance usage data from the plurality of geographically distributed water sensors, where each water sensor is located upstream of a plurality of water appliances in an associated distributed water infrastructure, and where each water sensor is configured to collect data from an infrastructure inlet flow reflective of operation of at least one specific category of water appliance downstream of the water sensor. The system may compare the water appliance usage data from the plurality of geographically distributed water sensors to determine trends in operation of the at least one specific category of water appliance across a population. The system may output information about the trends in operation.

Abstract: A fluid governing system including a fluid inlet and fluid inlet port coupleable to an upstream pipe segment; a fluid outlet and a fluid outlet port coupleable to a downstream pipe segment; a flow unit; a metering inlet path in flow communication with the fluid inlet; a metering outlet path in flow communication with the fluid outlet, the metering inlet path is in flow communication with the metering outlet path through the flow unit which is articulable between the metering inlet path and the metering outlet path; a pressure responsive sealing diaphragm for selective sealing a metering inlet port; an inlet chamber disposed at a face of the sealing diaphragm, the inlet chamber in flow communication with the fluid inlet; a control chamber disposed at an opposite face of the sealing diaphragm; and a control fluid duct extending between the inlet chamber and the control chamber.