Abstract: A system for permitting administration of an as-needed medication dose to a patient is disclosed herein. The system comprises a medication management server, a computing device associated with a healthcare provider and a dispenser associated with a patient. The dispenser in communication with the server is configured to dispense controlled medication at a minimum dosing interval. The dispenser comprises a controller in communication with the server configured to control the actuation of one or more events of the dispenser including a medication dispensation event. The computing device in communication with the server is configured to manage a quantity of the medication dose dispensed and the predefined dosing interval, remotely. The server is further configured to send an alert on tampering the dispenser or on detecting an out-of-communication state of dispenser for a predetermined time interval.