Patents by Inventor Shazia Sadiq
Shazia Sadiq has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8853244Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: GrantFiled: May 23, 2007Date of Patent: October 7, 2014Assignee: Vertex Pharmaceuticals IncorporatedInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 8399478Abstract: The present invention relates to compounds useful as inhibitors of protein kinase represented by formula (I): or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: GrantFiled: February 24, 2011Date of Patent: March 19, 2013Assignee: Vertex Pharmaceuticals IncorporatedInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, David Kay, Ronald Knegiel, Sharn Ramaya, Shazia Sadiq
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Patent number: 8312005Abstract: A semantically aware relational database management system includes suitable programming to relate attributes of the relational database to semantic equivalents of such attributes. In response to receiving a query, the relational database management system performs at least one semantically aware operation on the data in the relational database in order to determine what data is to be retrieved in response to the query. Results of the query presented to a user may include data derived from performing the semantically aware operations.Type: GrantFiled: December 31, 2009Date of Patent: November 13, 2012Assignee: SAP AGInventors: Maria E. Orlowska, Wasim Sadiq, Shazia Sadiq
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Publication number: 20120165378Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.Type: ApplicationFiled: September 16, 2011Publication date: June 28, 2012Applicant: VERTEX PHARMACEUTICALS INCORPORATEDInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 8188134Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: GrantFiled: September 28, 2010Date of Patent: May 29, 2012Assignee: Vertex Pharmaceuticals IncorporatedInventors: Guy Brenchley, Steven Durrant, Jean-Damien Charrier, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 8039661Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.Type: GrantFiled: November 9, 2010Date of Patent: October 18, 2011Assignee: Vertex Pharmaceuticals IncorporatedInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 8017781Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: GrantFiled: November 15, 2006Date of Patent: September 13, 2011Assignee: Vertex Pharmaceuticals IncorporatedInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq, Jingrong Cao
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Patent number: 8003806Abstract: The invention relates to compounds of the Formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X2, X4, X5 and X1 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of Formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of Formula 1.Type: GrantFiled: November 9, 2005Date of Patent: August 23, 2011Assignee: OSI Pharmaceuticals, LLCInventors: Jason Bloxham, Gary V. Borzillo, Eric William Collington, Shazia Sadiq, Colin Peter Sambrook Smith, Chris L. Waller, Graham M. Wynne
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Publication number: 20110190507Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.Type: ApplicationFiled: November 9, 2010Publication date: August 4, 2011Applicant: VERTEX PHARMACEUTICALS INCORPORATEDInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Publication number: 20110178146Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: ApplicationFiled: September 28, 2010Publication date: July 21, 2011Applicant: VERTEX PHARMACEUTICALS INCORPORATEDInventors: Guy Brenchley, Steven Durrant, Jean-Damien Charrier, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 7915305Abstract: The present invention relates to compounds useful as inhibitors of protein kinase represented by formula (I): or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: GrantFiled: January 23, 2007Date of Patent: March 29, 2011Assignee: Vertex Pharmaceuticals IncorporatedInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, David Kay, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 7885840Abstract: A flexible workflow is described that includes a pocket of flexibility. The pocket of flexibility may include workflow fragments that may be joined together, subject to pre-defined constraints. In implementing the flexible workflow, a user may encounter the pocket of flexibility, and select from the fragments to construct a workflow that is consistent with the user's current needs. The fragments may be incrementally presented to the user on a user interface, such that only those fragments determined to be combinable in a valid way may be selected by the user. In this way, a user who may have little experience with workflow languages or terminology may be able to use the flexible workflow, and be confident that the result is valid. Thus, difficulties in dealing with change in workflow systems may be mitigated, and this mitigation may be achieved without compromising the simplicity and generic nature of a workflow language.Type: GrantFiled: September 29, 2003Date of Patent: February 8, 2011Assignee: SAP AktiengesellschaftInventors: Shazia Sadiq, Wasim Sadiq, Maria E. Orlowska
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Patent number: 7851495Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.Type: GrantFiled: May 22, 2007Date of Patent: December 14, 2010Assignee: Vertex Pharmaceuticals IncorporatedInventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 7829590Abstract: The present invention relates to compounds useful as inhibitors of protein kinase, represented by structural formula I: or pharmaceutically acceptable salts thereof, wherein values of the variables of structural formula are as described in the specification and claims. The invention also provides pharmaceutically acceptable compositions comprising the compounds or salts, and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: GrantFiled: April 12, 2007Date of Patent: November 9, 2010Inventors: Guy Brenchley, Steven Durrant, Jean-Damien Charrier, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Publication number: 20100114894Abstract: A semantically aware relational database management system includes suitable programming to relate attributes of the relational database to semantic equivalents of such attributes. In response to receiving a query, the relational database management system performs at least one semantically aware operation on the data in the relational database in order to determine what data is to be retrieved in response to the query. Results of the query presented to a user may include data derived from performing the semantically aware operations.Type: ApplicationFiled: December 31, 2009Publication date: May 6, 2010Applicant: SAP AGInventors: Maria E. Orlowska, Wasim Sadiq, Shazia Sadiq
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Patent number: 7664762Abstract: A semantically aware relational database management system includes suitable programming to relate attributes of the relational database to semantic equivalents of such attributes. In response to receiving a query, the relational database management system performs at least one semantically aware operation on the data in the relational database in order to determine what data is to be retrieved in response to the query. Results of the query presented to a user may include data derived from performing the semantically aware operations.Type: GrantFiled: January 30, 2007Date of Patent: February 16, 2010Assignee: SAP AGInventors: Maria E. Orlowska, Wasim Sadiq, Shazia Sadiq
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Publication number: 20090286840Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.Type: ApplicationFiled: April 12, 2007Publication date: November 19, 2009Inventors: Guy Brenchley, Steven Durrant, Jean-Damien Charrier, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq
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Patent number: 7465726Abstract: Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least two of the Abl, Aurora-A, Blk, c-Raf, cSRC, Src, PRK2, FGFR3, Flt3, Lck, Mek1, PDK-1, GSK3?, EGFR, p70S6K, BMX, SGK, CaMKII, Tie-2, IGF-1R, Ron, Ret, and KDR kinases in animals, including humans, for the treatment and/or prevention of various diseases and conditions such as cancer.Type: GrantFiled: August 1, 2005Date of Patent: December 16, 2008Assignee: OSI Pharmaceuticals, Inc.Inventors: Saleh Ahmed, Oscar Barba, Jason Bloxham, Graham Dawson, William Gattrell, John Kitchin, Neil Anthony Pegg, Imaad Saba, Shazia Sadiq, Colin Peter Sambrook Smith, Don Smyth, Amo G. Steinig, Robin Wilkes, Bijoy Panicker, Paula Tavares, Matthew Cox, An-Hu Li, Hanqing Dong, Lifu Ma, Kenneth (‘Ken’) Foreman, Qinghua (‘Felix’) Weng, Kathryn Stolz
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Publication number: 20080183661Abstract: A semantically aware relational database management system includes suitable programming to relate attributes of the relational database to semantic equivalents of such attributes. In response to receiving a query, the relational database management system performs at least one semantically aware operation on the data in the relational database in order to determine what data is to be retrieved in response to the query. Results of the query presented to a user may include data derived from performing the semantically aware operations.Type: ApplicationFiled: January 30, 2007Publication date: July 31, 2008Applicant: SAP AGInventors: Maria E. Orlowska, Wasim Sadiq, Shazia Sadiq
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Publication number: 20080070965Abstract: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.Type: ApplicationFiled: May 22, 2007Publication date: March 20, 2008Inventors: Guy Brenchley, Jean-Damien Charrier, Steven Durrant, Ronald Knegtel, Sharn Ramaya, Shazia Sadiq