Patents by Inventor Sheau-Jiun Chang

Sheau-Jiun Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioactive fraction of TSYI-813 for treating or improving gastric ulcer, its preparation method and use thereof
    Patent number: 11179431
    Abstract: Present invention provides a bioactive fraction of Anisomeles indica, TSYI-813, and its preparation which includes extracting Anisomeles indica using an alcohol solvent, fractioning the extract of Anisomeles indica by an organic solvent and water, and purifying via a silica column chromatography with 10:1˜10:5 hexane/ethyl acetate for sequential elution to give the bioactive fraction of Anisomeles indica, TSYI-813. The bioactive fraction of Anisomeles indica, TSYI-813, disclosed in present invention can can be used as an effective ingredient for treating or improving gastric ulcers, including reducing the area of ulcer and inflammation in the stomach tissue.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: November 23, 2021
    Assignee: SYI BIOTECHNOLOGY CO., LTD.
    Inventors: Hsiu-Man Lien, Chia-Chang Chen, Sheau-Jiun Chang, Chao-Lu Huang
  • BIOACTIVE FRACTION OF Anisomeles indica TSYI-813 FOR TREATING OR IMPROVING GASTRIC ULCER, ITS PREPARATION METHOD AND USE THEREOF
    Publication number: 20210205391
    Abstract: Present invention provides a bioactive fraction of Anisomeles indica, TSYI-813, and its preparation which includes extracting Anisomeles indica using an alcohol solvent, fractioning the extract of Anisomeles indica by an organic solvent and water, and purifying via a silica column chromatography with 10:1˜10:5 hexane/ethyl acetate for sequential elution to give the bioactive fraction of Anisomeles indica, TSYI-813. The bioactive fraction of Anisomeles indica, TSYI-813, disclosed in present invention can can be used as an effective ingredient for treating or improving gastric ulcers, including reducing the area of ulcer and inflammation in the stomach tissue.
    Type: Application
    Filed: February 26, 2020
    Publication date: July 8, 2021
    Inventors: Hsiu-Man Lien, Chia-Chang Chen, Sheau-Jiun Chang, Chao-Lu Huang
  • USE OF OVATODIOLIDE FOR PREPARING A COMPOSITION FOR INHIBITING PROTEIN SYNTHESIS OF GASTRIC HELICOBACTER PYPORI
    Publication number: 20190358198
    Abstract: A use of ovatodiolide for preparing a composition used for inhibiting protein synthesis of gastric Helicobacter pylori, wherein the ovatodiolide achieves an effect of inhibiting gastric Helicobacter pylori by inhibiting the expression of 30S ribosomes RpsB of gastric Helicobacter pylori and further inhibiting its protein synthesis.
    Type: Application
    Filed: May 23, 2018
    Publication date: November 28, 2019
    Inventors: Hsiu-Man Lien, Chia-Chang Chen, Chih-Ho Lai, Sheau-Jiun Chang, Hui-Yu Wu
  • NATURAL COMPOSITION HAVING ALPHA-GLUCOSIDASE ACTIVITY INHIBITION EFFECT AND USED FOR REGULATING THE ABSORPTION OF BLOOD GLUCOSE AND CARBOHYDRATE
    Publication number: 20190209638
    Abstract: A natural composition that includes C. osmophloeum and C. pinnatifida. The C. osmophloeum is an aqueous extract of Cinnamomum osmophloeum leaves. The Crataegus pinnatifida is an aqueous extract of C. pinnatifida fruit. The weight ratio of the C. osmophloeum to the C. pinnatifida is 1:0.05-2, the preferred ratio is 1:0.5-1.5, and the optimal ratio is 1:0.9-1.1. The pharmaceutical composition has an ?-glucosidase inhibition effect. The natural composition can further inhibit ?-amylase to regulate the absorption of blood glucose and carbohydrate.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 11, 2019
    Inventors: Hsiu-Man Lien, Chia-Chang Chen, Sheau-Jiun Chang, Chao-Lu Huang, Jui-Ting Hsu