Patents by Inventor Sheila B. Bond

Sheila B. Bond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and kits for amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
    Patent number: 5792607
    Abstract: The present invention involves methods of improving LCR and PCR amplification schemes by modifying at least one probe/primer end so that the probability of the probe/prirner contributing to spurious signal development is greatly reduced. Only after specific hybridization of the modified probe/primer with true target, are the modified ends "corrected" in a target dependent fashion to allow participation of the probe/primer in the enzymatic assembly reaction. Specific modifications depend on whether the assembly is done by ligation (as in LCR) or by extension/elongation (as in PCR).
    Type: Grant
    Filed: March 28, 1995
    Date of Patent: August 11, 1998
    Assignee: Abbott Laboratories
    Inventors: Keith C. Backman, Sheila B. Bond, John J. Carrino, Thomas G. Laffler