Abstract: A dynamically configurable threat scanning machine management system is capable of tracking information associated with one ore more items and/or passengers. A central control computer network can transmit, among other things, operational software and threat profiles to the threat scanning machines, while the threat scanning machines can transmit, among other things, images and performance data to the central computer that can be distributed to one or more operator stations for review and analysis. The threat scanning machine management system can be arranged in a hierarchical manner, which enables threat scanning machines at various locations to be connected into regional, national or international control centers. The network may be wireless and the control computer may be portable, enabling a supervisor to remotely manage the system while remaining mobile. The tracked information allows, for example, comparison to other information to determine if an alarm or change in threat status is warranted.