Patents by Inventor Sheila N. BELLO-IRIZARRY

Sheila N. BELLO-IRIZARRY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Passive immunization for infections
    Patent number: 10100127
    Abstract: Disclosed herein are monoclonal antibodies or binding portion thereof that bind specifically to a Staphylococcus spp. autolysin N-acetylmuramoyl-L-alanine amidase catalytic domain and/or cell wall binding domain, as well as pharmaceutical compositions containing the same. Cell lines expressing the monoclonal antibodies, including hybridomas, are also disclosed. Methods of using the monoclonal antibodies for installation of orthopedic implants, grafts or medical devices, treating or preventing a Staphylococcus infection, and treating osteomyelitis are described, as are diagnostic methods for the detection of Staphylococcus in a sample.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: October 16, 2018
    Assignee: University of Rochester
    Inventors: John L. Daiss, Edward Schwarz, John J. Varrone, James Brodell, Jr., Sheila N. Bello-Irizarry
  • PASSIVE IMMUNIZATION FOR STAPHYLOCOCCUS INFECTIONS
    Publication number: 20160311925
    Abstract: Disclosed herein are monoclonal antibodies or binding portion thereof that bind specifically to a Staphylococcus spp. autolysin N-acetylmuramoyl-L-alanine amidase catalytic domain and/or cell wall binding domain, as well as pharmaceutical compositions containing the same. Cell lines expressing the monoclonal antibodies, including hybridomas, are also disclosed. Methods of using the monoclonal antibodies for installation of orthopedic implants, grafts or medical devices, treating or preventing a Staphylococcus infection, and treating osteomyelitis are described, as are diagnostic methods for the detection of Staphylococcus in a sample.
    Type: Application
    Filed: December 15, 2014
    Publication date: October 27, 2016
    Inventors: John L. DAISS, Edward SCHWARZ, John J. VARRONE, James BRODELL, Jr., Sheila N. BELLO-IRIZARRY