Patents by Inventor Sheila Nolan

Sheila Nolan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attenuated human parainfluenza virus, methods and uses thereof
    Patent number: 9034343
    Abstract: The invention provides self replicating infectious recombinant paramyxoviruses. The recombinant paramyxovirus preferably have one or more attenuating mutations. In some embodiments, the recombinant paramyxovirus has a separate variant polynucleotide encoding a P protein and a separate monocistronic polynucleotide encoding a V protein. In some embodiments, recombinant paramyxovirus have at least one temperature sensitive mutation and one non-temperature sensitive mutation. Also provided are compositions and methods for using the recombinant paramyxoviruses as described herein.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: May 19, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Mario H. Skiadopoulos, Brian R. Murphy, Peter L. Collins, Sheila Nolan
  • ATTENUATED HUMAN PARAINFLUENZA VIRUS, METHODS AND USES THEREOF
    Publication number: 20130052718
    Abstract: The invention provides self replicating infectious recombinant paramyxoviruses. The recombinant paramyxovirus preferably have one or more attenuating mutations. In some embodiments, the recombinant paramyxovirus has a separate variant polynucleotide encoding a P protein and a separate monocistronic polynucleotide encoding a V protein. In some embodiments, recombinant paramyxovirus have at least one temperature sensitive mutation and one non-temperature sensitive mutation. Also provided are compositions and methods for using the recombinant paramyxoviruses as described herein.
    Type: Application
    Filed: January 10, 2006
    Publication date: February 28, 2013
    Applicant: THE GOVERNMENT OF THE US, REPRESENTED BY THE SECRETARY , DEPT. OF HEALTH AND HUMAN SERVICES
    Inventors: Mario H. Skiadopoulos, Peter L. Collins, Sheila Nolan