Abstract: Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform: receiving a request for an order comprising one or more items; determining when the order is eligible for batch picking by finding one or more other orders comprising at least one of the one or more items; and when the order is determined to be eligible for batch picking with the one or more other orders: creating one or more clusters by clustering together (1) the at least one of the one or more items of the order and (2) the at least one of the one or more items of the one or more other orders; estimating, for each respective cluster of the one or more clusters, an estimated fulfillment time interval to make ready the order; and assigning each respective cluster of the one or more clusters to at least one respective picker of one or more respective pickers. Other embodiments are disclosed herein.

Abstract: Methods and systems and computer-readable media are provided for dual optimization of pick walk and tote fill rates in order picking. Embodiments provide improved order picking speed and quality by optimizing pick routing with consideration of both proximity constraints and tote value constraints. Tote value constraints can include constraints on carrying capacity, volume, size in a particular dimension, or weight capacity.

Abstract: The invention provides a system and method for a mobile-powered desktop ECG system configured for remote monitoring of a patient. Analog ECG waveforms from probes attached to a patient are shared with a base ECG unit. The received analog ECG waveforms are converted into digital ECG waveforms and shared with a smartphone that powers the base ECG unit. The digital ECG waveforms are processed in the smartphone through an ECG application and sent to a cloud. The ECG application enables the smartphone connect with a medical practitioner in case a medical emergency is detected.

Abstract: It is provided a method, including checking if an indication is received that a certificate installed in a communication entity is to be revoked at a revocation time in the future; preparing, if the indication is received, a first revocation list, wherein the first revocation list includes an identifier of the certificate and the revocation time; providing the first revocation list to the communication entity.

Abstract: It is provided a method, including checking if an indication is received that a certificate installed in a communication entity is to be revoked at a revocation time in the future; preparing, if the indication is received, a first revocation list, wherein the first revocation list includes an identifier of the certificate and the revocation time; providing the first revocation list to the communication entity.

Abstract: Embodiments of the invention provide techniques for increasing user engagement with video ads and content. The invention is not limited to video advertisements, but is applicable to any other content. Embodiments of the invention provide engagement formats that use interesting frames in a video or objects within video frames to increase user engagement in the video, one or more frames of the video, or any object within the video.

Abstract: There are provided measures for trust anchor update in a public key infrastructure. Such measures exemplarily comprise, for managing, in a network utilizing authentication based on certificates for secure connections between end entities, an update from an old trusted anchor certificate to a new trusted anchor certificate, wherein each of said trusted anchor certificates is a root point of a chain of certificates, providing, for a pre-migration period, said old trusted anchor certificate as valid, providing, for a migration period, said old trusted anchor certificate and said new trusted anchor certificate, coincidentally, as valid, and providing, for a post-migration period, said new trusted anchor certificate as valid.

Abstract: Embodiments of the invention provide a method and apparatus (“system”) that overcome the above-mentioned problems among others and provide an innovative solution aimed at creating an interactive, dynamic and effective multi-media object with HIP capabilities which may be used in online advertising, security, and user-defined security. The system leverages the existing HIP CAPTCHA real estate to create multi-media objects that guarantee a captivated audience, especially in online advertising. Combining interactive multi-media objects with HIP capabilities helps to meet a very critical need faced by advertisers and websites today—creating an effective impression of any multi-media object on a user (a guaranteed eyeball). Embodiments of the current invention introduce a variety of formats that involve interacting with a multi-media object to provide a more natural user interaction and ease of use while maintaining security.

Abstract: The present invention relates to novel mutants of Streptokinase, its functional fragments and covalently modified forms. Methods are provided for the preparation of the bacterial plasminogen activator protein, Streptokinase its muteins, species variants and their covalently modified variants that are characterized by improved therapeutic properties, such as increased proteolytic stability, extended plasma half-lives, reduced immuno-reactivity and enhanced fibrin clot specificity. The method involves either incorporating additional cysteine residues, or substituting cysteine residues for naturally occurring amino acids into non-essential regions of the protein such that the catalytic activity of the resultant protein remains largely unaltered. These cysteine variants were further modified by covalently attaching a cysteine reactive polymer such as polyethylene glycol (PEG) or sulfhydryl-reactive moieties from a group that includes fluorophore, spin labels or other small conjugates.

Abstract: Embodiments of the invention provide techniques for increasing user engagement with video ads and content. The invention is not limited to video advertisements, but is applicable to any other content. Embodiments of the invention provide engagement formats that use interesting frames in a video or objects within video frames to increase user engagement in the video, one or more frames of the video, or any object within the video.

Abstract: Embodiments of the invention provide a method and apparatus (“system”) that overcome the above-mentioned problems among others and provide an innovative solution aimed at creating an interactive, dynamic and effective multi-media object with HIP capabilities which may be used in online advertising, security, and user-defined security. The system leverages the existing HIP CAPTCHA real estate to create multi-media objects that guarantee a captivated audience, especially in online advertising. Combining interactive multi-media objects with HIP capabilities helps to meet a very critical need faced by advertisers and websites today—creating an effective impression of any multi-media object on a user (a guaranteed eyeball). Embodiments of the current invention introduce a variety of formats that involve interacting with a multi-media object to provide a more natural user interaction and ease of use while maintaining security.

Abstract: Embodiments of the invention provide techniques for increasing user engagement with video ads and content. The invention is not limited to video advertisements, but is applicable to any other content. Embodiments of the invention provide engagement formats that use interesting frames in a video or objects within video frames to increase user engagement in the video, one or more frames of the video, or any object within the video.

Abstract: A system and method provide digital online surveys and testing using interactive multi-media content with an option to enable and disable Human Interaction Proof (HIP) capabilities. The system uses random interactivity with multi-media content as HIP validation and subsequently make the user take a test or online survey. The system associates successful completion of tests to rewards. The rewards are awarded by publishers or stakeholders wanting to conduct the survey or test or by third party affiliates that are part of the exchange connecting the content provider and the advertiser wishing to conduct the test, with the option to enable and disable HIP capabilities. The system segments such tests and surveys across demographics. The system captures analytics as part of HIP along with testing and survey results. Such combined analytics have demographics as different dimensions. The system uses haptic technology for HIP and to complete the test or survey.

Abstract: The present invention relates to novel mutants of Streptokinase, its functional fragments and covalently modified forms. Methods are provided for the preparation of the bacterial plasminogen activator protein, Streptokinase its muteins, species variants and their covalently modified variants that are characterized by improved therapeutic properties, such as increased proteolytic stability, extended plasma half-lives, reduced immuno-reactivity and enhanced fibrin clot specificity. The method involves either incorporating additional cysteine residues, or substituting cysteine residues for naturally occurring amino acids into non-essential regions of the protein such that the catalytic activity of the resultant protein remains largely unaltered. These cysteine variants were further modified by covalently attaching a cysteine reactive polymer such as polyethylene glycol (PEG) or sulfhydryl-reactive moieties from a group that includes fluorophore, spin labels or other small conjugates.

Abstract: The present invention relates to novel mutants of Streptokinase, its functional fragments and covalently modified forms. Methods are provided for the preparation of the bacterial plasminogen activator protein, Streptokinase its muteins, species variants and their covalently modified variants that are characterized by improved therapeutic properties, such as increased proteolytic stability, extended plasma half-lives, reduced immuno-reactivity and enhanced fibrin clot specificity. The method involves either incorporating additional cysteine residues, or substituting cysteine residues for naturally occurring amino acids into non-essential regions of the protein such that the catalytic activity of the resultant protein remains largely unaltered. These cysteine variants were further modified by covalently attaching a cysteine reactive polymer such as polyethylene glycol (PEG) or sulfhydryl-reactive moieties from a group that includes fluorophore, spin labels or other small conjugates.

Abstract: Embodiments of the invention provide techniques for increasing user engagement with video ads and content. The invention is not limited to video advertisements, but is applicable to any other content. Embodiments of the invention provide engagement formats that use interesting frames in a video or objects within video frames to increase user engagement in the video, one or more frames of the video, or any object within the video.

Abstract: A system and method provide digital online surveys and testing using interactive multi-media content with an option to enable and disable Human Interaction Proof (HIP) capabilities. The system may use random interactivity with multi-media content as HIP validation and subsequently make the user take a test or online survey. The system may associate successful completion of tests to rewards, awarded by publishers or stakeholders wanting to conduct surveys or tests or by third party affiliates that are part of the exchange connecting the content provider and the advertiser wishing to conduct the test, with the option to enable and disable HIP capabilities. The system may segment such tests and surveys across demographics. The system may capture analytics as part of HIP along with testing and survey results. Combined analytics may have demographics as different dimensions. The system may use haptic technology for HIP and to complete the test or survey.

Abstract: Embodiments of the invention provide a method and apparatus (“system”) that overcome the above-mentioned problems among others and provide an innovative solution aimed at creating an interactive, dynamic and effective multi-media object with HIP capabilities which may be used in online advertising, security, and user-defined security. The system leverages the existing HIP CAPTCHA real estate to create multi-media objects that guarantee a captivated audience, especially in online advertising. Combining interactive multi-media objects with HIP capabilities helps to meet a very critical need faced by advertisers and websites today—creating an effective impression of any multi-media object on a user (a guaranteed eyeball). Embodiments of the current invention introduce a variety of formats that involve interacting with a multi-media object to provide a more natural user interaction and ease of use while maintaining security.

Abstract: The present invention relates to novel mutants of Streptokinase, its functional fragments and covalently modified forms. Methods are provided for the preparation of the bacterial plasminogen activator protein, Streptokinase its muteins, species variants and their covalently modified variants that are characterized by improved therapeutic properties, such as increased proteolytic stability, extended plasma half-lives, reduced immuno-reactivity and enhanced fibrin clot specificity. The method involves either incorporating additional cysteine residues, or substituting cysteine residues for naturally occurring amino acids into non-essential regions of the protein such that the catalytic activity of the resultant protein remains largely unaltered. These cysteine variants were further modified by covalently attaching a cysteine reactive polymer such as polyethylene glycol (PEG) or sulfhydryl-reactive moieties from a group that includes fluorophore, spin labels or other small conjugates.

Abstract: The present invention relates to novel mutants of Streptokinase, its functional fragments and covalently modified forms. Methods are provided for the preparation of the bacterial plasminogen activator protein, Streptokinase its muteins, species variants and their covalently modified variants that are characterized by improved therapeutic properties, such as increased proteolytic stability, extended plasma half-lives, reduced immuno-reactivity and enhanced fibrin clot specificity. The method involves either incorporating additional cysteine residues, or substituting cysteine residues for naturally occurring amino acids into non-essential regions of the protein such that the catalytic activity of the resultant protein remains largely unaltered. These cysteine variants were further modified by covalently attaching a cysteine reactive polymer such as polyethylene glycol (PEG) or sulfhydryl-reactive moieties from a group that includes fluorophore, spin labels or other small conjugates.