Patents by Inventor Shelby P. Umland

Shelby P. Umland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Histamine receptor
    Patent number: 7547523
    Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: June 16, 2009
    Assignee: Schering Corporation
    Inventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick James Monsma, Jr., Kelley L. Morse, Shelby P. Umland, Suke Wang
  • Histamine receptor antibody
    Patent number: 7166705
    Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.
    Type: Grant
    Filed: July 8, 2003
    Date of Patent: January 23, 2007
    Assignee: Schering Corporation
    Inventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang
  • Peptide substrates of a proteolytic ADAM33 polypeptide and assays using the same
    Patent number: 7067273
    Abstract: The present invention discloses peptide substrates of a proteolytic ADAM33 polypeptide. The present invention also discloses methods of identifying additional substrates of a proteolytic ADAM33 polypeptide. Furthermore, the present invention discloses methods of identifying compounds that inhibit the proteolytic activity of a proteolytic ADAM33 polypeptide.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: June 27, 2006
    Assignee: Schering Corporation
    Inventors: Rumin Zhang, Jun Zou, Feng X. Zhu, James P. Durkin, William T. Windsor, Shelby P. Umland
  • Peptide substrates of a proteolytic ADAM33 polypeptide and assays using the same
    Publication number: 20040152869
    Abstract: The present invention discloses peptide substrates of a proteolytic ADAM33 polypeptide. The present invention also discloses methods of identifying additional substrates of a proteolytic ADAM33 polypeptide. Furthermore, the present invention discloses methods of identifying compounds that inhibit the proteolytic activity of a proteolytic ADAM33 polypeptide.
    Type: Application
    Filed: December 19, 2003
    Publication date: August 5, 2004
    Applicant: Schering Corporation
    Inventors: Rumin Zhang, Jun Zou, Feng X. Zhu, James P. Durkin, William T. Windsor, Shelby P. Umland
  • Histamine receptor
    Patent number: 6613533
    Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: September 2, 2003
    Assignee: Schering Corporation
    Inventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang
  • Histamine receptor
    Publication number: 20020098539
    Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.
    Type: Application
    Filed: March 19, 2001
    Publication date: July 25, 2002
    Inventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang
  • Polynucleotide encoding a histamine receptor
    Patent number: 6204017
    Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: March 20, 2001
    Assignee: Schering Corporation
    Inventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang