Patents by Inventor Sheldon R. Pinnell
Sheldon R. Pinnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9248082Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.Type: GrantFiled: April 15, 2009Date of Patent: February 2, 2016Assignee: L'OREALInventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
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Publication number: 20090286874Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.Type: ApplicationFiled: April 15, 2009Publication date: November 19, 2009Applicant: L'OREALInventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
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Publication number: 20070225360Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.Type: ApplicationFiled: March 20, 2007Publication date: September 27, 2007Applicant: L'OREALInventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
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Patent number: 7179841Abstract: The present invention relates to ascorbic acid single-phase solution compositions that provide enhanced stability, enhanced solubility and an enhanced photoprotective effect as compared to prior compositions. The compositions comprise L-ascorbic acid; a cinnamic acid derivative such as p-coumaric acid, ferulic acid, caffeic acid, sinapinic acid, a derivative thereof, and a combination thereof; a solvent comprising a glycol ether and an alkanediol; and water; the composition having a pH of no more than about 3.5. The compositions may also comprise a form of Vitamin E and are useful for treatment of radical-induced damage to a subject, particularly the skin of a subject.Type: GrantFiled: January 11, 2005Date of Patent: February 20, 2007Assignee: L'Oreal USA Creative, Inc.Inventors: Jan E. Zielinski, Sheldon R. Pinnell
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Patent number: 7160560Abstract: A skin-care composition containing a protective component providing protection of the skin from environmental damage and regulating natural moisture of the skin; a skin firming component; and a barrier component. Thus, the composition includes at least one component that supports the collagen structure, and at least one component that supports the body's own defense/repair mechanisms, and most preferably, at least one component that supports the skin lipid system.Type: GrantFiled: October 23, 2003Date of Patent: January 9, 2007Assignee: L'Oreal S.A.Inventor: Sheldon R. Pinnell
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Patent number: 6743449Abstract: A non-aqueous method of extracting olive leaves, and products formed containing the olive-leaf extract. The resulting extract is used, preferably together with vitamins C, E and A or components thereof to form a skin treatment product that has efficacy as a photoprotectant and antioxidant.Type: GrantFiled: February 13, 2002Date of Patent: June 1, 2004Assignee: Skinceuticals, Inc.Inventors: Sheldon R. Pinnell, Mostafa M. Omar
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Publication number: 20030152656Abstract: A non-aqueous method of extracting olive leaves, and products formed containing the olive-leaf extract. The resulting extract is used, preferably together with vitamins C, E and A or components thereof to form a skin treatment product that has efficacy as a photoprotectant and antioxidant.Type: ApplicationFiled: February 13, 2002Publication date: August 14, 2003Inventors: Sheldon R. Pinnell, Mostafa M. Omar
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Patent number: 6524599Abstract: The present invention relates to the use of compositions comprising the extract of the milk thistle plant, Silybum marianum, soybean protein and alpha tocopherol, either singly or in combination, in novel compositions for topical application on skin, hair and nails. More specifically, the present invention pertains to compositions for the above use, which are suitable for the entire skin. The present invention pertains to compositions for the above use, which are characterized in that they comprise milk thistle extract, soybean protein, and alpha tocopherol, either individually or in combination.Type: GrantFiled: June 29, 2001Date of Patent: February 25, 2003Assignee: Skinceuticals, Inc.Inventor: Sheldon R. Pinnell
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Publication number: 20020155074Abstract: The present invention relates to the use of compositions comprising the extract of the milk thistle plant, Silybum marianum, soybean protein and alpha tocopherol, either singly or in combination, in novel compositions for topical application on skin, hair and nails. More specifically, the present invention pertains to compositions for the above use, which are suitable for the entire skin. The present invention pertains to compositions for the above use, which are characterized in that they comprise milk thistle extract, soybean protein, and alpha tocopherol, either individually or in combination.Type: ApplicationFiled: June 29, 2001Publication date: October 24, 2002Inventor: Sheldon R. Pinnell
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Patent number: 6005009Abstract: Methods of inhibiting fibrosis comprising administering certain pyridoxal benzoyl hydrazones or analogs thereof are disclosed. Preferred hydrazones are pyridoxal benzoyl hydrazone, 3-hydroxyisonicotinaldehyde benzoyl hydrazone and salicylaldehyde benzoyl hydrazone. The methods are useful in treating fibrosing disorders, including dermal fibrosing disorders, fibrosis of internal organs and fibrotic conditions of the eye.Type: GrantFiled: March 20, 1997Date of Patent: December 21, 1999Assignee: Duke UniversityInventors: Saood Murad, Sheldon R. Pinnell, Huanshu Yang
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Patent number: 5571846Abstract: Disclosed is a method of inhibiting fibrosis in a human or animal subject afflicted with a fibrosing disorder. The method comprises administering to the subject an effective fibrosis-inhibiting amount of a compound of Formula (I): ##STR1## wherein: n is 1 or 2;R is selected from the group consisting of hydrogen, C1-C4 alkyl, hydroxy, amino, and nitro; andR' is selected from the group consisting of hydrogen and C1-C4 alkyl.or a pharmaceutically acceptable salt thereof. Preferred as a compound of Formula (I) is benzoic hydrazide. Pharmaceutical formulations and the use of compounds of Formula (I) for making the same are also disclosed.Type: GrantFiled: December 7, 1994Date of Patent: November 5, 1996Assignee: Duke UniversityInventors: Saood Murad, Sheldon R. Pinnell
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Patent number: 5374660Abstract: Disclosed is a method of inhibiting fibrosis in a human or animal subject afflicted with a fibrosing disorder. The method comprises administering to the subject an effective fibrosis-inhibiting amount of a compound of Formula (I): ##STR1## wherein: n is 1 or 2;R is selected from the group consisting of hydrogen, C1-C4 alkyl, hydroxy, amino, and nitro; andR' is selected from the group consisting of hydrogen and C1-C4 alkyl.or a pharmaceutically acceptable salt thereof. Preferred as a compound of Formula (I) is benzoic hydrazide. Pharmaceutical formulations and the use of compounds of Formula (I) for making the same are also disclosed.Type: GrantFiled: February 16, 1993Date of Patent: December 20, 1994Assignee: Duke UniversityInventors: Saood Murad, Sheldon R. Pinnell
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Patent number: 5328913Abstract: The present invention relates to a method of inhibiting cell proliferation and lysyl hydroxylase expression. The method involves the use of minoxidil derivatives. The inhibitory activity of hydroxy derivatives of minoxidil is such that these compounds can be used as selective antifibrotic agents.Type: GrantFiled: December 11, 1992Date of Patent: July 12, 1994Assignee: Duke UniversityInventors: Saood Murad, Sheldon R. Pinnell
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Patent number: 5140043Abstract: Stable topical aqueous compositions are provided containing a concentration of L-ascorbic acid above about 1% (W/V) and maintaining a pH below about 3.5.Type: GrantFiled: April 17, 1989Date of Patent: August 18, 1992Assignee: Duke UniversityInventors: Douglas Darr, Sheldon R. Pinnell
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Patent number: 4645668Abstract: The method for preventing and for treating mammalian cicatrices such as keloids, acne scars, hypertrophic scars, wrinkles, cellulite and neoplastic fibrosis which comprises intra-dermal injection of effective amounts of a pharmacologically suitable solution of the enzymes collagenase, elastase, papain, plasminogen activator, plasmin, mast cell protease or lysosomal hydrolase, individually, and one or more of such enzymes in combination with the enzyme hyaluronidase.Type: GrantFiled: March 27, 1985Date of Patent: February 24, 1987Assignee: Biospecifics, NVInventor: Sheldon R. Pinnell
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Patent number: 4524065Abstract: A method for the prevention of and for the dissolution of mammalian cicatrices such as acne scars, keloids and other hypertrophic scars comprising intralesional injection of effective amounts of a pharmacologically suitable solution of the enzyme collagenase, by itself, and collagenase in combination with the enzyme hyaluronidase.Type: GrantFiled: August 4, 1983Date of Patent: June 18, 1985Assignee: Bio-Specifics N.V.Inventor: Sheldon R. Pinnell