Patents by Inventor Shelley Russek

Shelley Russek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Effect of steroids on NMDA receptors depends on subunit composition
    Publication number: 20040204490
    Abstract: Disclosed is a method for identifying a subunit specific modulator of the N-methyl-D-aspartate (NMDA) receptor. The method involves providing a plurality of NMDA receptors which differ in their subunit identity. The receptors are contacted with a neurotransmitter recognition site ligand in the presence and absence of a candidate modulator. Receptor activity is then assayed, with an increase or decrease in activity in at least one, but not all members of the plurality of NMDA receptors, in the presence but not the absence of a candidate modulator, being an indication that the candidate modulator is a subunit specific modulator. The subunit identity of the subset of the NMDA receptors to determine the subunit specificity of the candidate modulator. Various combinations of NMDA receptor subunits are provided.
    Type: Application
    Filed: July 25, 2003
    Publication date: October 14, 2004
    Inventors: David H. Farb, Shelley Russek, Ming-Kuei Jang, Terrell T. Gibbs, Nader Yaghoubi
  • Methods for identifying a subunit specific modulator of N-methyl-D-asparate receptor
    Patent number: 6623933
    Abstract: Disclosed is a method for identifying a subunit specific modulator of the N-methyl-D-aspartate (NMDA) receptor. The method involves providing a plurality of NMDA receptors which differ in their subunit identity. The receptors are contacted with a neurotransmitter recognition site ligand in the presence and absence of a candidate modulator. Receptor activity is then assayed, with an increase or decrease in activity in at least one, but not all members of the plurality of NMDA receptors, in the presence but not the absence of a candidate modulator, being an indication that the candidate modulator is a subunit specific modulator. The subunit identity of the subset of the NMDA receptors to determine the subunit specificity of the candidate modulator. Various combinations of NMDA receptor subunits are provided.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: September 23, 2003
    Assignee: Trustees of Boston University
    Inventors: David H. Farb, Nader Yaghoubi, Shelley Russek, Ming-Kuei Jang, Terrell T. Gibbs